| Full name: chromosome 12 open reading frame 42 | Alias Symbol: FLJ25323 | ||
| Type: protein-coding gene | Cytoband: 12q23.2 | ||
| Entrez ID: 374470 | HGNC ID: HGNC:24729 | Ensembl Gene: ENSG00000179088 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf42 | 374470 | 1561378_at | -0.2432 | 0.3040 | |
| GSE26886 | C12orf42 | 374470 | 239977_at | 0.3464 | 0.0055 | |
| GSE45670 | C12orf42 | 374470 | 239977_at | 0.1101 | 0.1015 | |
| GSE53622 | C12orf42 | 374470 | 8237 | -0.4066 | 0.0169 | |
| GSE53624 | C12orf42 | 374470 | 8237 | 0.3198 | 0.0003 | |
| GSE63941 | C12orf42 | 374470 | 1561378_at | -0.1219 | 0.3411 | |
| GSE77861 | C12orf42 | 374470 | 1561378_at | -0.2207 | 0.0173 | |
| GSE97050 | C12orf42 | 374470 | A_33_P3316661 | 0.1483 | 0.5767 | |
| TCGA | C12orf42 | 374470 | RNAseq | 1.6581 | 0.0084 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C12orf42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf42 | 374470 | 3 | 2 | 25 | |
| GSE20123 | C12orf42 | 374470 | 3 | 2 | 25 | |
| GSE43470 | C12orf42 | 374470 | 2 | 0 | 41 | |
| GSE46452 | C12orf42 | 374470 | 9 | 1 | 49 | |
| GSE47630 | C12orf42 | 374470 | 9 | 1 | 30 | |
| GSE54993 | C12orf42 | 374470 | 0 | 5 | 65 | |
| GSE54994 | C12orf42 | 374470 | 4 | 2 | 47 | |
| GSE60625 | C12orf42 | 374470 | 0 | 0 | 11 | |
| GSE74703 | C12orf42 | 374470 | 2 | 0 | 34 | |
| GSE74704 | C12orf42 | 374470 | 1 | 2 | 17 | |
| TCGA | C12orf42 | 374470 | 19 | 10 | 67 |
Total number of gains: 52; Total number of losses: 25; Total Number of normals: 411.
Somatic mutations of C12orf42:
Generating mutation plots.
Highly correlated genes for C12orf42:
Showing top 20/32 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf42 | ODF4 | 0.691314 | 3 | 0 | 3 |
| C12orf42 | KRT20 | 0.644983 | 3 | 0 | 3 |
| C12orf42 | GUCY2C | 0.643183 | 5 | 0 | 3 |
| C12orf42 | MUC2 | 0.642495 | 4 | 0 | 4 |
| C12orf42 | GABBR2 | 0.628325 | 3 | 0 | 3 |
| C12orf42 | CD300LG | 0.627032 | 3 | 0 | 3 |
| C12orf42 | INSL3 | 0.625558 | 4 | 0 | 3 |
| C12orf42 | PTCH1 | 0.619081 | 3 | 0 | 3 |
| C12orf42 | COX4I2 | 0.617331 | 3 | 0 | 3 |
| C12orf42 | SHD | 0.616504 | 4 | 0 | 3 |
| C12orf42 | DENND1C | 0.613004 | 4 | 0 | 4 |
| C12orf42 | TIMD4 | 0.603703 | 4 | 0 | 4 |
| C12orf42 | CCKBR | 0.601834 | 3 | 0 | 3 |
| C12orf42 | LAIR2 | 0.588848 | 3 | 0 | 3 |
| C12orf42 | GPR78 | 0.58575 | 4 | 0 | 3 |
| C12orf42 | TUBA8 | 0.585626 | 4 | 0 | 3 |
| C12orf42 | CBLN4 | 0.581081 | 4 | 0 | 3 |
| C12orf42 | WFIKKN2 | 0.576789 | 3 | 0 | 3 |
| C12orf42 | KIF6 | 0.572829 | 4 | 0 | 3 |
| C12orf42 | TERT | 0.571433 | 4 | 0 | 3 |
For details and further investigation, click here
