| Full name: ribulose-5-phosphate-3-epimerase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q34 | ||
| Entrez ID: 6120 | HGNC ID: HGNC:10293 | Ensembl Gene: ENSG00000197713 | OMIM ID: 180480 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPE | 6120 | 225040_s_at | -0.1317 | 0.8757 | |
| GSE20347 | RPE | 6120 | 221770_at | -0.1455 | 0.4661 | |
| GSE23400 | RPE | 6120 | 221770_at | 0.2542 | 0.0000 | |
| GSE26886 | RPE | 6120 | 225040_s_at | -0.5018 | 0.0464 | |
| GSE29001 | RPE | 6120 | 221770_at | 0.1723 | 0.6845 | |
| GSE38129 | RPE | 6120 | 221770_at | 0.1092 | 0.5097 | |
| GSE45670 | RPE | 6120 | 225040_s_at | 0.2071 | 0.1479 | |
| GSE53622 | RPE | 6120 | 8738 | 0.3250 | 0.0000 | |
| GSE53624 | RPE | 6120 | 8738 | 0.3316 | 0.0000 | |
| GSE63941 | RPE | 6120 | 225040_s_at | -0.0555 | 0.8796 | |
| GSE77861 | RPE | 6120 | 225040_s_at | -0.1172 | 0.6493 | |
| GSE97050 | RPE | 6120 | A_33_P3281940 | 0.3229 | 0.3640 | |
| SRP007169 | RPE | 6120 | RNAseq | -0.0307 | 0.9238 | |
| SRP008496 | RPE | 6120 | RNAseq | 0.0752 | 0.6867 | |
| SRP064894 | RPE | 6120 | RNAseq | 0.1359 | 0.4016 | |
| SRP133303 | RPE | 6120 | RNAseq | 0.2640 | 0.0386 | |
| SRP159526 | RPE | 6120 | RNAseq | -0.1529 | 0.4806 | |
| SRP193095 | RPE | 6120 | RNAseq | -0.3442 | 0.0048 | |
| SRP219564 | RPE | 6120 | RNAseq | -0.0701 | 0.7282 | |
| TCGA | RPE | 6120 | RNAseq | 0.1089 | 0.0495 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPE | 6120 | 2 | 12 | 16 | |
| GSE20123 | RPE | 6120 | 2 | 12 | 16 | |
| GSE43470 | RPE | 6120 | 1 | 6 | 36 | |
| GSE46452 | RPE | 6120 | 0 | 5 | 54 | |
| GSE47630 | RPE | 6120 | 4 | 5 | 31 | |
| GSE54993 | RPE | 6120 | 0 | 3 | 67 | |
| GSE54994 | RPE | 6120 | 9 | 9 | 35 | |
| GSE60625 | RPE | 6120 | 0 | 3 | 8 | |
| GSE74703 | RPE | 6120 | 1 | 5 | 30 | |
| GSE74704 | RPE | 6120 | 2 | 6 | 12 | |
| TCGA | RPE | 6120 | 12 | 24 | 60 |
Total number of gains: 33; Total number of losses: 90; Total Number of normals: 365.
Somatic mutations of RPE:
Generating mutation plots.
Highly correlated genes for RPE:
Showing top 20/438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPE | TTC8 | 0.811549 | 3 | 0 | 3 |
| RPE | ATOX1 | 0.760421 | 3 | 0 | 3 |
| RPE | EIF5A | 0.742194 | 3 | 0 | 3 |
| RPE | NEK7 | 0.733473 | 3 | 0 | 3 |
| RPE | HSD17B12 | 0.731699 | 3 | 0 | 3 |
| RPE | TMCC3 | 0.730875 | 3 | 0 | 3 |
| RPE | COMMD1 | 0.718786 | 3 | 0 | 3 |
| RPE | EXOC6B | 0.711226 | 4 | 0 | 4 |
| RPE | PTGR1 | 0.709374 | 3 | 0 | 3 |
| RPE | PSME1 | 0.708983 | 3 | 0 | 3 |
| RPE | MB21D2 | 0.70364 | 3 | 0 | 3 |
| RPE | INTS12 | 0.701384 | 4 | 0 | 4 |
| RPE | PSMC1 | 0.699976 | 3 | 0 | 3 |
| RPE | FAM83G | 0.699079 | 3 | 0 | 3 |
| RPE | MTCH2 | 0.698096 | 5 | 0 | 4 |
| RPE | EIF2B4 | 0.695892 | 3 | 0 | 3 |
| RPE | FBXO11 | 0.69142 | 3 | 0 | 3 |
| RPE | FAHD1 | 0.688761 | 5 | 0 | 4 |
| RPE | EIF3I | 0.685067 | 6 | 0 | 6 |
| RPE | SRFBP1 | 0.679862 | 4 | 0 | 3 |
For details and further investigation, click here
