| Full name: ring finger protein 111 | Alias Symbol: ARK|Arkadia|FLJ38008|DKFZP761D081 | ||
| Type: protein-coding gene | Cytoband: 15q22.1-q22.2 | ||
| Entrez ID: 54778 | HGNC ID: HGNC:17384 | Ensembl Gene: ENSG00000157450 | OMIM ID: 605840 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNF111:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF111 | 54778 | 218761_at | -0.8470 | 0.3525 | |
| GSE20347 | RNF111 | 54778 | 218761_at | -0.4297 | 0.0306 | |
| GSE23400 | RNF111 | 54778 | 218761_at | -0.1620 | 0.0384 | |
| GSE26886 | RNF111 | 54778 | 218761_at | -0.3392 | 0.1464 | |
| GSE29001 | RNF111 | 54778 | 218761_at | -0.3403 | 0.4061 | |
| GSE38129 | RNF111 | 54778 | 218761_at | -0.2282 | 0.1200 | |
| GSE45670 | RNF111 | 54778 | 218761_at | -0.3229 | 0.0050 | |
| GSE53622 | RNF111 | 54778 | 50489 | -0.1327 | 0.0353 | |
| GSE53624 | RNF111 | 54778 | 50489 | -0.4035 | 0.0000 | |
| GSE63941 | RNF111 | 54778 | 218761_at | -0.8569 | 0.0055 | |
| GSE77861 | RNF111 | 54778 | 218761_at | -0.0311 | 0.9379 | |
| GSE97050 | RNF111 | 54778 | A_23_P77160 | -0.1078 | 0.7163 | |
| SRP007169 | RNF111 | 54778 | RNAseq | -0.7766 | 0.0320 | |
| SRP008496 | RNF111 | 54778 | RNAseq | -0.7211 | 0.0002 | |
| SRP064894 | RNF111 | 54778 | RNAseq | -0.3875 | 0.0648 | |
| SRP133303 | RNF111 | 54778 | RNAseq | -0.0253 | 0.7950 | |
| SRP159526 | RNF111 | 54778 | RNAseq | -0.5789 | 0.0459 | |
| SRP193095 | RNF111 | 54778 | RNAseq | -0.1103 | 0.1916 | |
| SRP219564 | RNF111 | 54778 | RNAseq | -0.2240 | 0.5923 | |
| TCGA | RNF111 | 54778 | RNAseq | -0.0037 | 0.9419 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF111 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF111:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF111 | 54778 | 6 | 4 | 20 | |
| GSE20123 | RNF111 | 54778 | 6 | 3 | 21 | |
| GSE43470 | RNF111 | 54778 | 4 | 4 | 35 | |
| GSE46452 | RNF111 | 54778 | 3 | 7 | 49 | |
| GSE47630 | RNF111 | 54778 | 8 | 10 | 22 | |
| GSE54993 | RNF111 | 54778 | 5 | 6 | 59 | |
| GSE54994 | RNF111 | 54778 | 6 | 8 | 39 | |
| GSE60625 | RNF111 | 54778 | 4 | 0 | 7 | |
| GSE74703 | RNF111 | 54778 | 4 | 3 | 29 | |
| GSE74704 | RNF111 | 54778 | 2 | 3 | 15 | |
| TCGA | RNF111 | 54778 | 10 | 17 | 69 |
Total number of gains: 58; Total number of losses: 65; Total Number of normals: 365.
Somatic mutations of RNF111:
Generating mutation plots.
Highly correlated genes for RNF111:
Showing top 20/717 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF111 | RAB18 | 0.800613 | 3 | 0 | 3 |
| RNF111 | FAM162B | 0.785262 | 3 | 0 | 3 |
| RNF111 | TANC1 | 0.781362 | 3 | 0 | 3 |
| RNF111 | RBM7 | 0.761106 | 5 | 0 | 5 |
| RNF111 | EIF3I | 0.758334 | 3 | 0 | 3 |
| RNF111 | HUS1 | 0.753563 | 3 | 0 | 3 |
| RNF111 | CDNF | 0.747214 | 3 | 0 | 3 |
| RNF111 | CAMK2D | 0.742374 | 4 | 0 | 4 |
| RNF111 | USP45 | 0.723009 | 3 | 0 | 3 |
| RNF111 | SIAE | 0.720992 | 3 | 0 | 3 |
| RNF111 | FNIP2 | 0.715853 | 3 | 0 | 3 |
| RNF111 | PSMD8 | 0.714517 | 3 | 0 | 3 |
| RNF111 | PCSK5 | 0.709913 | 3 | 0 | 3 |
| RNF111 | BMPR2 | 0.709088 | 3 | 0 | 3 |
| RNF111 | ZNF25 | 0.708737 | 3 | 0 | 3 |
| RNF111 | COMMD1 | 0.700026 | 4 | 0 | 4 |
| RNF111 | CLIP4 | 0.695606 | 4 | 0 | 3 |
| RNF111 | KCNK6 | 0.687797 | 3 | 0 | 3 |
| RNF111 | DTWD1 | 0.684654 | 6 | 0 | 5 |
| RNF111 | TRPC6 | 0.684468 | 3 | 0 | 3 |
For details and further investigation, click here
