| Full name: transmembrane protein 72 | Alias Symbol: bA285G1.3|KSP37 | ||
| Type: protein-coding gene | Cytoband: 10q11.21 | ||
| Entrez ID: 643236 | HGNC ID: HGNC:31658 | Ensembl Gene: ENSG00000187783 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM72 | 643236 | 1558323_at | -0.1282 | 0.5366 | |
| GSE26886 | TMEM72 | 643236 | 1558323_at | 0.0227 | 0.8572 | |
| GSE45670 | TMEM72 | 643236 | 1558324_a_at | -0.0578 | 0.5434 | |
| GSE53622 | TMEM72 | 643236 | 59544 | -0.1815 | 0.2383 | |
| GSE53624 | TMEM72 | 643236 | 59544 | -0.1305 | 0.1674 | |
| GSE63941 | TMEM72 | 643236 | 1558324_a_at | 0.1187 | 0.5055 | |
| GSE77861 | TMEM72 | 643236 | 1558324_a_at | -0.1466 | 0.1813 | |
| TCGA | TMEM72 | 643236 | RNAseq | -4.0288 | 0.0283 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM72 | 643236 | 3 | 5 | 22 | |
| GSE20123 | TMEM72 | 643236 | 3 | 5 | 22 | |
| GSE43470 | TMEM72 | 643236 | 1 | 6 | 36 | |
| GSE46452 | TMEM72 | 643236 | 0 | 13 | 46 | |
| GSE47630 | TMEM72 | 643236 | 4 | 12 | 24 | |
| GSE54993 | TMEM72 | 643236 | 9 | 0 | 61 | |
| GSE54994 | TMEM72 | 643236 | 2 | 10 | 41 | |
| GSE60625 | TMEM72 | 643236 | 0 | 0 | 11 | |
| GSE74703 | TMEM72 | 643236 | 1 | 3 | 32 | |
| GSE74704 | TMEM72 | 643236 | 2 | 4 | 14 | |
| TCGA | TMEM72 | 643236 | 17 | 17 | 62 |
Total number of gains: 42; Total number of losses: 75; Total Number of normals: 371.
Somatic mutations of TMEM72:
Generating mutation plots.
Highly correlated genes for TMEM72:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM72 | LINC00491 | 0.631742 | 3 | 0 | 3 |
| TMEM72 | CLYBL-AS1 | 0.622383 | 3 | 0 | 3 |
| TMEM72 | DEFB118 | 0.607664 | 4 | 0 | 3 |
| TMEM72 | KRT71 | 0.600638 | 3 | 0 | 3 |
| TMEM72 | TCL6 | 0.596876 | 3 | 0 | 3 |
| TMEM72 | LIMD1-AS1 | 0.588599 | 3 | 0 | 3 |
| TMEM72 | PAPPA2 | 0.581143 | 3 | 0 | 3 |
| TMEM72 | HTR3C | 0.578105 | 3 | 0 | 3 |
| TMEM72 | OTC | 0.572179 | 4 | 0 | 3 |
| TMEM72 | TMC2 | 0.567787 | 3 | 0 | 3 |
| TMEM72 | ACBD4 | 0.563126 | 4 | 0 | 3 |
| TMEM72 | IRGC | 0.54963 | 3 | 0 | 3 |
| TMEM72 | SLAMF6 | 0.532884 | 4 | 0 | 3 |
| TMEM72 | SENCR | 0.531355 | 3 | 0 | 3 |
| TMEM72 | KLLN | 0.529043 | 5 | 0 | 3 |
| TMEM72 | RBPMS-AS1 | 0.527167 | 4 | 0 | 3 |
| TMEM72 | ACACB | 0.522565 | 5 | 0 | 3 |
| TMEM72 | VWA3A | 0.522081 | 5 | 0 | 3 |
| TMEM72 | PRB1 | 0.514394 | 4 | 0 | 3 |
| TMEM72 | COL4A4 | 0.513362 | 4 | 0 | 3 |
For details and further investigation, click here
