| Full name: ornithine carbamoyltransferase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp11.4 | ||
| Entrez ID: 5009 | HGNC ID: HGNC:8512 | Ensembl Gene: ENSG00000036473 | OMIM ID: 300461 |
| Drug and gene relationship at DGIdb | |||
Expression of OTC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTC | 5009 | 207200_at | -0.0991 | 0.6021 | |
| GSE20347 | OTC | 5009 | 207200_at | -0.0564 | 0.4201 | |
| GSE23400 | OTC | 5009 | 207200_at | -0.1108 | 0.0512 | |
| GSE26886 | OTC | 5009 | 207200_at | -0.0033 | 0.9778 | |
| GSE29001 | OTC | 5009 | 207200_at | -0.0993 | 0.6495 | |
| GSE38129 | OTC | 5009 | 207200_at | -0.1584 | 0.0101 | |
| GSE45670 | OTC | 5009 | 207200_at | -0.0165 | 0.8890 | |
| GSE53622 | OTC | 5009 | 118436 | -0.8169 | 0.0000 | |
| GSE53624 | OTC | 5009 | 118436 | -0.3454 | 0.0004 | |
| GSE63941 | OTC | 5009 | 207200_at | 0.2075 | 0.1357 | |
| GSE77861 | OTC | 5009 | 207200_at | -0.0955 | 0.3700 | |
| TCGA | OTC | 5009 | RNAseq | -3.9408 | 0.0118 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by OTC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTC:
No record found for this gene.
Somatic mutations of OTC:
Generating mutation plots.
Highly correlated genes for OTC:
Showing top 20/360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTC | LMAN1L | 0.675988 | 3 | 0 | 3 |
| OTC | PTPRN2 | 0.674492 | 5 | 0 | 3 |
| OTC | SIRPG | 0.658533 | 3 | 0 | 3 |
| OTC | FGF10 | 0.656913 | 3 | 0 | 3 |
| OTC | MYL1 | 0.654677 | 6 | 0 | 5 |
| OTC | PRIMA1 | 0.646519 | 3 | 0 | 3 |
| OTC | SMR3B | 0.637568 | 5 | 0 | 4 |
| OTC | CXCL12 | 0.636398 | 3 | 0 | 3 |
| OTC | RUNX1T1 | 0.635347 | 5 | 0 | 4 |
| OTC | TEX15 | 0.634702 | 4 | 0 | 4 |
| OTC | PRR34 | 0.631568 | 5 | 0 | 5 |
| OTC | CPB2 | 0.628144 | 4 | 0 | 4 |
| OTC | RNF144A-AS1 | 0.625578 | 3 | 0 | 3 |
| OTC | LYVE1 | 0.622686 | 5 | 0 | 5 |
| OTC | CACNA1H | 0.62012 | 3 | 0 | 3 |
| OTC | SYT2 | 0.619914 | 6 | 0 | 5 |
| OTC | BPY2 | 0.61989 | 4 | 0 | 3 |
| OTC | SOX5 | 0.619769 | 3 | 0 | 3 |
| OTC | MYRIP | 0.619138 | 4 | 0 | 3 |
| OTC | CARNS1 | 0.61728 | 4 | 0 | 4 |
For details and further investigation, click here
