| Full name: transmembrane protein 91 | Alias Symbol: FLJ27310|IFITMD6|DSPC3 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 641649 | HGNC ID: HGNC:32393 | Ensembl Gene: | OMIM ID: 618294 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM91:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM91 | 641649 | 229957_at | -0.0809 | 0.8790 | |
| GSE26886 | TMEM91 | 641649 | 229957_at | 0.2710 | 0.2989 | |
| GSE45670 | TMEM91 | 641649 | 229957_at | 0.1472 | 0.3340 | |
| GSE53622 | TMEM91 | 641649 | 32998 | 0.1791 | 0.0706 | |
| GSE53624 | TMEM91 | 641649 | 32998 | -0.0687 | 0.4658 | |
| GSE63941 | TMEM91 | 641649 | 229957_at | -0.1294 | 0.6970 | |
| GSE77861 | TMEM91 | 641649 | 229957_at | -0.2149 | 0.1780 | |
| GSE97050 | TMEM91 | 641649 | A_33_P3363620 | 0.1929 | 0.4552 | |
| SRP007169 | TMEM91 | 641649 | RNAseq | -1.5116 | 0.0013 | |
| SRP064894 | TMEM91 | 641649 | RNAseq | 0.8827 | 0.0136 | |
| SRP133303 | TMEM91 | 641649 | RNAseq | -0.2066 | 0.4194 | |
| SRP159526 | TMEM91 | 641649 | RNAseq | 0.1729 | 0.4492 | |
| SRP193095 | TMEM91 | 641649 | RNAseq | 0.0220 | 0.9266 | |
| TCGA | TMEM91 | 641649 | RNAseq | 0.3013 | 0.0397 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM91 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM91:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM91 | 641649 | 4 | 4 | 22 | |
| GSE20123 | TMEM91 | 641649 | 4 | 3 | 23 | |
| GSE43470 | TMEM91 | 641649 | 3 | 11 | 29 | |
| GSE46452 | TMEM91 | 641649 | 48 | 1 | 10 | |
| GSE47630 | TMEM91 | 641649 | 9 | 5 | 26 | |
| GSE54993 | TMEM91 | 641649 | 17 | 4 | 49 | |
| GSE54994 | TMEM91 | 641649 | 7 | 11 | 35 | |
| GSE60625 | TMEM91 | 641649 | 9 | 0 | 2 | |
| GSE74703 | TMEM91 | 641649 | 3 | 7 | 26 | |
| GSE74704 | TMEM91 | 641649 | 4 | 1 | 15 | |
| TCGA | TMEM91 | 641649 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 63; Total Number of normals: 303.
Somatic mutations of TMEM91:
Generating mutation plots.
Highly correlated genes for TMEM91:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM91 | EXOC3L4 | 0.753358 | 3 | 0 | 3 |
| TMEM91 | FBLN7 | 0.666472 | 3 | 0 | 3 |
| TMEM91 | ERP44 | 0.627185 | 3 | 0 | 3 |
| TMEM91 | CAPN13 | 0.613737 | 3 | 0 | 3 |
| TMEM91 | NGB | 0.610431 | 3 | 0 | 3 |
| TMEM91 | GNAS-AS1 | 0.608052 | 3 | 0 | 3 |
| TMEM91 | PKLR | 0.600555 | 4 | 0 | 3 |
| TMEM91 | SLC5A8 | 0.576608 | 3 | 0 | 3 |
| TMEM91 | PLEKHN1 | 0.575971 | 3 | 0 | 3 |
| TMEM91 | SEC14L2 | 0.574066 | 5 | 0 | 3 |
| TMEM91 | COL16A1 | 0.568235 | 4 | 0 | 3 |
| TMEM91 | SNX8 | 0.565574 | 3 | 0 | 3 |
| TMEM91 | DGCR6L | 0.562124 | 3 | 0 | 3 |
| TMEM91 | NOXA1 | 0.557904 | 4 | 0 | 3 |
| TMEM91 | MGAT5B | 0.554217 | 3 | 0 | 3 |
| TMEM91 | PDCD1 | 0.553408 | 4 | 0 | 3 |
| TMEM91 | CPT1C | 0.553305 | 4 | 0 | 3 |
| TMEM91 | ABCA7 | 0.54884 | 6 | 0 | 5 |
| TMEM91 | JAKMIP1 | 0.543395 | 3 | 0 | 3 |
| TMEM91 | TUBGCP6 | 0.540055 | 4 | 0 | 3 |
For details and further investigation, click here
