| Full name: TNF receptor superfamily member 8 | Alias Symbol: KI-1 | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 943 | HGNC ID: HGNC:11923 | Ensembl Gene: ENSG00000120949 | OMIM ID: 153243 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFRSF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFRSF8 | 943 | 206729_at | -0.0123 | 0.9763 | |
| GSE20347 | TNFRSF8 | 943 | 206729_at | -0.0259 | 0.7516 | |
| GSE23400 | TNFRSF8 | 943 | 206729_at | -0.1625 | 0.0009 | |
| GSE26886 | TNFRSF8 | 943 | 206729_at | -0.0126 | 0.9207 | |
| GSE29001 | TNFRSF8 | 943 | 206729_at | 0.0363 | 0.8749 | |
| GSE38129 | TNFRSF8 | 943 | 206729_at | -0.0919 | 0.1563 | |
| GSE45670 | TNFRSF8 | 943 | 206729_at | 0.0338 | 0.7824 | |
| GSE53622 | TNFRSF8 | 943 | 10091 | 0.6156 | 0.0000 | |
| GSE53624 | TNFRSF8 | 943 | 10091 | 1.3061 | 0.0000 | |
| GSE63941 | TNFRSF8 | 943 | 206729_at | -0.0385 | 0.9315 | |
| GSE77861 | TNFRSF8 | 943 | 206729_at | -0.0852 | 0.5100 | |
| GSE97050 | TNFRSF8 | 943 | A_23_P500614 | 0.2901 | 0.2372 | |
| SRP064894 | TNFRSF8 | 943 | RNAseq | 1.2395 | 0.0025 | |
| SRP133303 | TNFRSF8 | 943 | RNAseq | 1.0742 | 0.0167 | |
| SRP159526 | TNFRSF8 | 943 | RNAseq | 1.1082 | 0.0523 | |
| SRP193095 | TNFRSF8 | 943 | RNAseq | 0.6033 | 0.0993 | |
| TCGA | TNFRSF8 | 943 | RNAseq | -0.4165 | 0.1991 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TNFRSF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFRSF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFRSF8 | 943 | 0 | 5 | 25 | |
| GSE20123 | TNFRSF8 | 943 | 0 | 4 | 26 | |
| GSE43470 | TNFRSF8 | 943 | 4 | 6 | 33 | |
| GSE46452 | TNFRSF8 | 943 | 7 | 1 | 51 | |
| GSE47630 | TNFRSF8 | 943 | 8 | 4 | 28 | |
| GSE54993 | TNFRSF8 | 943 | 3 | 1 | 66 | |
| GSE54994 | TNFRSF8 | 943 | 11 | 4 | 38 | |
| GSE60625 | TNFRSF8 | 943 | 0 | 0 | 11 | |
| GSE74703 | TNFRSF8 | 943 | 3 | 4 | 29 | |
| GSE74704 | TNFRSF8 | 943 | 0 | 0 | 20 | |
| TCGA | TNFRSF8 | 943 | 10 | 22 | 64 |
Total number of gains: 46; Total number of losses: 51; Total Number of normals: 391.
Somatic mutations of TNFRSF8:
Generating mutation plots.
Highly correlated genes for TNFRSF8:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFRSF8 | CD14 | 0.747716 | 3 | 0 | 3 |
| TNFRSF8 | C1QA | 0.743065 | 3 | 0 | 3 |
| TNFRSF8 | SPI1 | 0.7412 | 3 | 0 | 3 |
| TNFRSF8 | TYROBP | 0.733167 | 3 | 0 | 3 |
| TNFRSF8 | FCGR3A | 0.729644 | 3 | 0 | 3 |
| TNFRSF8 | SLC35E3 | 0.725991 | 3 | 0 | 3 |
| TNFRSF8 | NRSN2 | 0.722067 | 3 | 0 | 3 |
| TNFRSF8 | LY96 | 0.720334 | 3 | 0 | 3 |
| TNFRSF8 | ARPC1B | 0.71493 | 3 | 0 | 3 |
| TNFRSF8 | CD163 | 0.708343 | 3 | 0 | 3 |
| TNFRSF8 | POLN | 0.705393 | 3 | 0 | 3 |
| TNFRSF8 | ZNF208 | 0.701353 | 3 | 0 | 3 |
| TNFRSF8 | IKBIP | 0.698643 | 3 | 0 | 3 |
| TNFRSF8 | APOBR | 0.698471 | 4 | 0 | 3 |
| TNFRSF8 | PLD6 | 0.69634 | 3 | 0 | 3 |
| TNFRSF8 | NAP1L5 | 0.69591 | 3 | 0 | 3 |
| TNFRSF8 | HERC5 | 0.695431 | 3 | 0 | 3 |
| TNFRSF8 | CERKL | 0.692592 | 3 | 0 | 3 |
| TNFRSF8 | AVPR1A | 0.691323 | 5 | 0 | 5 |
| TNFRSF8 | CHIC1 | 0.688806 | 3 | 0 | 3 |
For details and further investigation, click here
