| Full name: MX dynamin like GTPase 2 | Alias Symbol: MXB | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 4600 | HGNC ID: HGNC:7533 | Ensembl Gene: ENSG00000183486 | OMIM ID: 147890 |
| Drug and gene relationship at DGIdb | |||
Expression of MX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MX2 | 4600 | 204994_at | -0.2726 | 0.7999 | |
| GSE20347 | MX2 | 4600 | 204994_at | 0.6923 | 0.0324 | |
| GSE23400 | MX2 | 4600 | 204994_at | 0.3270 | 0.0097 | |
| GSE26886 | MX2 | 4600 | 204994_at | -0.0785 | 0.8894 | |
| GSE29001 | MX2 | 4600 | 204994_at | 1.0891 | 0.0036 | |
| GSE38129 | MX2 | 4600 | 204994_at | 0.5336 | 0.0685 | |
| GSE45670 | MX2 | 4600 | 204994_at | 1.6372 | 0.0005 | |
| GSE53622 | MX2 | 4600 | 9786 | 0.5372 | 0.0012 | |
| GSE53624 | MX2 | 4600 | 9786 | 0.8632 | 0.0000 | |
| GSE63941 | MX2 | 4600 | 204994_at | -1.2857 | 0.3304 | |
| GSE77861 | MX2 | 4600 | 204994_at | 0.2457 | 0.6571 | |
| GSE97050 | MX2 | 4600 | A_33_P3278200 | 0.0434 | 0.8932 | |
| SRP007169 | MX2 | 4600 | RNAseq | 1.2438 | 0.0212 | |
| SRP008496 | MX2 | 4600 | RNAseq | 0.9342 | 0.0214 | |
| SRP064894 | MX2 | 4600 | RNAseq | 1.6918 | 0.0000 | |
| SRP133303 | MX2 | 4600 | RNAseq | 0.4778 | 0.0751 | |
| SRP159526 | MX2 | 4600 | RNAseq | -0.1244 | 0.8916 | |
| SRP193095 | MX2 | 4600 | RNAseq | 1.0335 | 0.0000 | |
| SRP219564 | MX2 | 4600 | RNAseq | -0.1588 | 0.8580 | |
| TCGA | MX2 | 4600 | RNAseq | 0.0380 | 0.7929 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by MX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MX2 | 4600 | 2 | 8 | 20 | |
| GSE20123 | MX2 | 4600 | 2 | 8 | 20 | |
| GSE43470 | MX2 | 4600 | 0 | 13 | 30 | |
| GSE46452 | MX2 | 4600 | 1 | 21 | 37 | |
| GSE47630 | MX2 | 4600 | 6 | 17 | 17 | |
| GSE54993 | MX2 | 4600 | 8 | 1 | 61 | |
| GSE54994 | MX2 | 4600 | 3 | 8 | 42 | |
| GSE60625 | MX2 | 4600 | 0 | 0 | 11 | |
| GSE74703 | MX2 | 4600 | 0 | 10 | 26 | |
| GSE74704 | MX2 | 4600 | 1 | 4 | 15 | |
| TCGA | MX2 | 4600 | 6 | 41 | 49 |
Total number of gains: 29; Total number of losses: 131; Total Number of normals: 328.
Somatic mutations of MX2:
Generating mutation plots.
Highly correlated genes for MX2:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MX2 | VASH2 | 0.746055 | 3 | 0 | 3 |
| MX2 | IFIT3 | 0.721244 | 11 | 0 | 10 |
| MX2 | TNN | 0.695475 | 4 | 0 | 3 |
| MX2 | PARP10 | 0.670358 | 6 | 0 | 5 |
| MX2 | OASL | 0.655864 | 8 | 0 | 6 |
| MX2 | HELZ2 | 0.645712 | 4 | 0 | 3 |
| MX2 | ISG15 | 0.641251 | 11 | 0 | 9 |
| MX2 | UBE2L6 | 0.637016 | 10 | 0 | 8 |
| MX2 | FANCF | 0.632777 | 3 | 0 | 3 |
| MX2 | OAS3 | 0.623855 | 9 | 0 | 6 |
| MX2 | IFIT2 | 0.617928 | 11 | 0 | 6 |
| MX2 | LAT | 0.596212 | 4 | 0 | 3 |
| MX2 | ATF7IP2 | 0.590748 | 5 | 0 | 3 |
| MX2 | LGALS3BP | 0.579024 | 8 | 0 | 6 |
| MX2 | BATF2 | 0.572183 | 8 | 0 | 4 |
| MX2 | KLC4 | 0.556715 | 3 | 0 | 3 |
| MX2 | NLRC5 | 0.556475 | 7 | 0 | 5 |
| MX2 | PSMB9 | 0.552738 | 11 | 0 | 5 |
| MX2 | SDS | 0.552233 | 5 | 0 | 3 |
| MX2 | GZMB | 0.535917 | 9 | 0 | 6 |
For details and further investigation, click here
