| Full name: torsin family 1 member B | Alias Symbol: DQ1|MGC4386 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 27348 | HGNC ID: HGNC:11995 | Ensembl Gene: ENSG00000136816 | OMIM ID: 608050 |
| Drug and gene relationship at DGIdb | |||
Expression of TOR1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOR1B | 27348 | 209593_s_at | 0.2653 | 0.2097 | |
| GSE20347 | TOR1B | 27348 | 209593_s_at | 0.2162 | 0.0500 | |
| GSE23400 | TOR1B | 27348 | 209593_s_at | 0.3841 | 0.0000 | |
| GSE26886 | TOR1B | 27348 | 209593_s_at | 0.7285 | 0.0053 | |
| GSE29001 | TOR1B | 27348 | 209593_s_at | 0.5040 | 0.1297 | |
| GSE38129 | TOR1B | 27348 | 209593_s_at | 0.3160 | 0.0003 | |
| GSE45670 | TOR1B | 27348 | 209593_s_at | 0.4054 | 0.0049 | |
| GSE53622 | TOR1B | 27348 | 49387 | 0.4721 | 0.0000 | |
| GSE53624 | TOR1B | 27348 | 115123 | 0.5885 | 0.0000 | |
| GSE63941 | TOR1B | 27348 | 209593_s_at | -0.7047 | 0.1393 | |
| GSE77861 | TOR1B | 27348 | 209593_s_at | 0.2788 | 0.1129 | |
| GSE97050 | TOR1B | 27348 | A_33_P3231472 | 0.3734 | 0.2574 | |
| SRP007169 | TOR1B | 27348 | RNAseq | 1.5141 | 0.0003 | |
| SRP008496 | TOR1B | 27348 | RNAseq | 1.3850 | 0.0000 | |
| SRP064894 | TOR1B | 27348 | RNAseq | 0.7558 | 0.0000 | |
| SRP133303 | TOR1B | 27348 | RNAseq | 0.7049 | 0.0014 | |
| SRP159526 | TOR1B | 27348 | RNAseq | 0.4295 | 0.0183 | |
| SRP193095 | TOR1B | 27348 | RNAseq | 0.3182 | 0.0051 | |
| SRP219564 | TOR1B | 27348 | RNAseq | 0.1095 | 0.7280 | |
| TCGA | TOR1B | 27348 | RNAseq | 0.0569 | 0.3061 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TOR1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOR1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOR1B | 27348 | 6 | 9 | 15 | |
| GSE20123 | TOR1B | 27348 | 6 | 9 | 15 | |
| GSE43470 | TOR1B | 27348 | 5 | 7 | 31 | |
| GSE46452 | TOR1B | 27348 | 6 | 13 | 40 | |
| GSE47630 | TOR1B | 27348 | 3 | 16 | 21 | |
| GSE54993 | TOR1B | 27348 | 3 | 3 | 64 | |
| GSE54994 | TOR1B | 27348 | 12 | 9 | 32 | |
| GSE60625 | TOR1B | 27348 | 0 | 0 | 11 | |
| GSE74703 | TOR1B | 27348 | 5 | 5 | 26 | |
| GSE74704 | TOR1B | 27348 | 3 | 7 | 10 | |
| TCGA | TOR1B | 27348 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of TOR1B:
Generating mutation plots.
Highly correlated genes for TOR1B:
Showing top 20/1202 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOR1B | MIB1 | 0.761185 | 3 | 0 | 3 |
| TOR1B | ZNF655 | 0.758629 | 3 | 0 | 3 |
| TOR1B | CYTH3 | 0.739738 | 3 | 0 | 3 |
| TOR1B | FAM168A | 0.736596 | 3 | 0 | 3 |
| TOR1B | SPPL2A | 0.736164 | 3 | 0 | 3 |
| TOR1B | HIC1 | 0.72425 | 3 | 0 | 3 |
| TOR1B | AURKAIP1 | 0.720162 | 3 | 0 | 3 |
| TOR1B | MFF | 0.717038 | 3 | 0 | 3 |
| TOR1B | NCBP1 | 0.71643 | 9 | 0 | 8 |
| TOR1B | RBBP6 | 0.702775 | 4 | 0 | 3 |
| TOR1B | HNRNPA1 | 0.699645 | 3 | 0 | 3 |
| TOR1B | ZSCAN12 | 0.699013 | 3 | 0 | 3 |
| TOR1B | ARL13B | 0.697099 | 5 | 0 | 4 |
| TOR1B | PLEKHO2 | 0.694763 | 3 | 0 | 3 |
| TOR1B | TATDN1 | 0.694423 | 4 | 0 | 4 |
| TOR1B | NPHP3 | 0.69303 | 3 | 0 | 3 |
| TOR1B | TEAD2 | 0.687712 | 3 | 0 | 3 |
| TOR1B | SDHB | 0.683148 | 3 | 0 | 3 |
| TOR1B | TRIM21 | 0.682217 | 4 | 0 | 4 |
| TOR1B | TLR1 | 0.67894 | 3 | 0 | 3 |
For details and further investigation, click here
