| Full name: lysozyme | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q15 | ||
| Entrez ID: 4069 | HGNC ID: HGNC:6740 | Ensembl Gene: ENSG00000090382 | OMIM ID: 153450 |
| Drug and gene relationship at DGIdb | |||
Expression of LYZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYZ | 4069 | 213975_s_at | -0.3079 | 0.8712 | |
| GSE20347 | LYZ | 4069 | 213975_s_at | -0.3082 | 0.5616 | |
| GSE23400 | LYZ | 4069 | 213975_s_at | 0.1308 | 0.6209 | |
| GSE26886 | LYZ | 4069 | 213975_s_at | -0.9954 | 0.1325 | |
| GSE29001 | LYZ | 4069 | 213975_s_at | -0.1591 | 0.8048 | |
| GSE38129 | LYZ | 4069 | 213975_s_at | -0.1356 | 0.7587 | |
| GSE45670 | LYZ | 4069 | 213975_s_at | -0.5078 | 0.3581 | |
| GSE63941 | LYZ | 4069 | 1555745_a_at | -0.1421 | 0.2338 | |
| GSE77861 | LYZ | 4069 | 213975_s_at | 0.1989 | 0.7730 | |
| SRP007169 | LYZ | 4069 | RNAseq | 1.9251 | 0.0094 | |
| SRP008496 | LYZ | 4069 | RNAseq | 0.0831 | 0.7239 | |
| SRP064894 | LYZ | 4069 | RNAseq | -0.2202 | 0.6811 | |
| SRP133303 | LYZ | 4069 | RNAseq | -0.6140 | 0.1837 | |
| SRP159526 | LYZ | 4069 | RNAseq | 0.5125 | 0.6429 | |
| SRP193095 | LYZ | 4069 | RNAseq | -1.9480 | 0.0015 | |
| SRP219564 | LYZ | 4069 | RNAseq | 1.4047 | 0.0093 | |
| TCGA | LYZ | 4069 | RNAseq | -0.4171 | 0.0037 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by LYZ expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LYZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYZ | 4069 | 6 | 1 | 23 | |
| GSE20123 | LYZ | 4069 | 6 | 0 | 24 | |
| GSE43470 | LYZ | 4069 | 5 | 0 | 38 | |
| GSE46452 | LYZ | 4069 | 11 | 1 | 47 | |
| GSE47630 | LYZ | 4069 | 10 | 1 | 29 | |
| GSE54993 | LYZ | 4069 | 0 | 6 | 64 | |
| GSE54994 | LYZ | 4069 | 7 | 1 | 45 | |
| GSE60625 | LYZ | 4069 | 0 | 0 | 11 | |
| GSE74703 | LYZ | 4069 | 5 | 0 | 31 | |
| GSE74704 | LYZ | 4069 | 5 | 0 | 15 | |
| TCGA | LYZ | 4069 | 23 | 8 | 65 |
Total number of gains: 78; Total number of losses: 18; Total Number of normals: 392.
Somatic mutations of LYZ:
Generating mutation plots.
Highly correlated genes for LYZ:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYZ | C1orf162 | 0.749951 | 3 | 0 | 3 |
| LYZ | TRAF3IP3 | 0.711625 | 4 | 0 | 4 |
| LYZ | SIGLEC10 | 0.711052 | 3 | 0 | 3 |
| LYZ | SPOCK2 | 0.701429 | 3 | 0 | 3 |
| LYZ | GIMAP2 | 0.693877 | 4 | 0 | 4 |
| LYZ | MPEG1 | 0.689784 | 4 | 0 | 4 |
| LYZ | CYTIP | 0.689605 | 7 | 0 | 7 |
| LYZ | RCSD1 | 0.685606 | 3 | 0 | 3 |
| LYZ | FLI1 | 0.681678 | 4 | 0 | 4 |
| LYZ | LAPTM5 | 0.681129 | 8 | 0 | 7 |
| LYZ | EVI2A | 0.679287 | 8 | 0 | 7 |
| LYZ | PTPRC | 0.678908 | 8 | 0 | 8 |
| LYZ | C16orf54 | 0.677049 | 3 | 0 | 3 |
| LYZ | EVI2B | 0.676287 | 9 | 0 | 8 |
| LYZ | CD84 | 0.673074 | 6 | 0 | 5 |
| LYZ | CD53 | 0.663234 | 10 | 0 | 8 |
| LYZ | APBB1IP | 0.64851 | 4 | 0 | 3 |
| LYZ | CTSS | 0.648459 | 8 | 0 | 7 |
| LYZ | MS4A6A | 0.642839 | 7 | 0 | 5 |
| LYZ | HLA-DMA | 0.641523 | 8 | 0 | 6 |
For details and further investigation, click here
