| Full name: trafficking protein particle complex 5 | Alias Symbol: MGC52424|TRS31 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126003 | HGNC ID: HGNC:23067 | Ensembl Gene: ENSG00000181029 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TRAPPC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAPPC5 | 126003 | 225870_s_at | 0.1545 | 0.5671 | |
| GSE26886 | TRAPPC5 | 126003 | 225870_s_at | 0.8025 | 0.0000 | |
| GSE45670 | TRAPPC5 | 126003 | 225870_s_at | 0.0848 | 0.5136 | |
| GSE63941 | TRAPPC5 | 126003 | 225870_s_at | -0.2662 | 0.4508 | |
| GSE77861 | TRAPPC5 | 126003 | 225870_s_at | -0.0190 | 0.9466 | |
| GSE97050 | TRAPPC5 | 126003 | A_32_P99432 | 0.2803 | 0.2458 | |
| SRP007169 | TRAPPC5 | 126003 | RNAseq | -1.0081 | 0.0028 | |
| SRP008496 | TRAPPC5 | 126003 | RNAseq | -0.6138 | 0.0059 | |
| SRP064894 | TRAPPC5 | 126003 | RNAseq | 0.4693 | 0.2447 | |
| SRP133303 | TRAPPC5 | 126003 | RNAseq | -0.2286 | 0.0793 | |
| SRP159526 | TRAPPC5 | 126003 | RNAseq | -0.3001 | 0.1472 | |
| SRP193095 | TRAPPC5 | 126003 | RNAseq | -0.4807 | 0.0000 | |
| SRP219564 | TRAPPC5 | 126003 | RNAseq | 0.1274 | 0.7657 | |
| TCGA | TRAPPC5 | 126003 | RNAseq | 0.1515 | 0.0359 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRAPPC5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TRAPPC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAPPC5 | 126003 | 5 | 3 | 22 | |
| GSE20123 | TRAPPC5 | 126003 | 4 | 2 | 24 | |
| GSE43470 | TRAPPC5 | 126003 | 2 | 6 | 35 | |
| GSE46452 | TRAPPC5 | 126003 | 47 | 1 | 11 | |
| GSE47630 | TRAPPC5 | 126003 | 5 | 7 | 28 | |
| GSE54993 | TRAPPC5 | 126003 | 16 | 3 | 51 | |
| GSE54994 | TRAPPC5 | 126003 | 6 | 13 | 34 | |
| GSE60625 | TRAPPC5 | 126003 | 9 | 0 | 2 | |
| GSE74703 | TRAPPC5 | 126003 | 2 | 4 | 30 | |
| GSE74704 | TRAPPC5 | 126003 | 1 | 2 | 17 | |
| TCGA | TRAPPC5 | 126003 | 9 | 20 | 67 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of TRAPPC5:
Generating mutation plots.
Highly correlated genes for TRAPPC5:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAPPC5 | SMARCD1 | 0.732374 | 3 | 0 | 3 |
| TRAPPC5 | SURF2 | 0.715391 | 3 | 0 | 3 |
| TRAPPC5 | STX5 | 0.709434 | 3 | 0 | 3 |
| TRAPPC5 | TBX20 | 0.705414 | 3 | 0 | 3 |
| TRAPPC5 | POP7 | 0.697623 | 3 | 0 | 3 |
| TRAPPC5 | CNPY3 | 0.693425 | 3 | 0 | 3 |
| TRAPPC5 | ZNF628 | 0.685188 | 3 | 0 | 3 |
| TRAPPC5 | ITGB4 | 0.679901 | 3 | 0 | 3 |
| TRAPPC5 | SF3B2 | 0.677277 | 3 | 0 | 3 |
| TRAPPC5 | HDAC7 | 0.676861 | 3 | 0 | 3 |
| TRAPPC5 | POLRMT | 0.673917 | 3 | 0 | 3 |
| TRAPPC5 | HOXB7 | 0.673559 | 3 | 0 | 3 |
| TRAPPC5 | SMYD5 | 0.671164 | 3 | 0 | 3 |
| TRAPPC5 | PTDSS2 | 0.667335 | 3 | 0 | 3 |
| TRAPPC5 | DNAJC4 | 0.661809 | 3 | 0 | 3 |
| TRAPPC5 | THAP7 | 0.659425 | 4 | 0 | 4 |
| TRAPPC5 | ILF3 | 0.657094 | 3 | 0 | 3 |
| TRAPPC5 | SPSB2 | 0.654408 | 4 | 0 | 4 |
| TRAPPC5 | C9orf16 | 0.652466 | 4 | 0 | 3 |
| TRAPPC5 | B4GALT7 | 0.651596 | 5 | 0 | 4 |
For details and further investigation, click here
