| Full name: tripartite motif containing 54 | Alias Symbol: MURF|MURF-3 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 57159 | HGNC ID: HGNC:16008 | Ensembl Gene: ENSG00000138100 | OMIM ID: 606474 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM54 | 57159 | 233669_s_at | 0.0834 | 0.7511 | |
| GSE26886 | TRIM54 | 57159 | 233669_s_at | 0.3089 | 0.0149 | |
| GSE45670 | TRIM54 | 57159 | 233669_s_at | -0.0228 | 0.7956 | |
| GSE53622 | TRIM54 | 57159 | 94441 | 0.0875 | 0.7136 | |
| GSE53624 | TRIM54 | 57159 | 94441 | 0.3206 | 0.0183 | |
| GSE63941 | TRIM54 | 57159 | 233669_s_at | -0.0060 | 0.9767 | |
| GSE77861 | TRIM54 | 57159 | 233669_s_at | -0.0783 | 0.6161 | |
| TCGA | TRIM54 | 57159 | RNAseq | 3.5960 | 0.0027 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRIM54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM54 | 57159 | 11 | 2 | 17 | |
| GSE20123 | TRIM54 | 57159 | 11 | 2 | 17 | |
| GSE43470 | TRIM54 | 57159 | 3 | 1 | 39 | |
| GSE46452 | TRIM54 | 57159 | 3 | 4 | 52 | |
| GSE47630 | TRIM54 | 57159 | 8 | 0 | 32 | |
| GSE54993 | TRIM54 | 57159 | 0 | 6 | 64 | |
| GSE54994 | TRIM54 | 57159 | 10 | 0 | 43 | |
| GSE60625 | TRIM54 | 57159 | 0 | 3 | 8 | |
| GSE74703 | TRIM54 | 57159 | 3 | 0 | 33 | |
| GSE74704 | TRIM54 | 57159 | 9 | 1 | 10 | |
| TCGA | TRIM54 | 57159 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of TRIM54:
Generating mutation plots.
Highly correlated genes for TRIM54:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM54 | REG3A | 0.713138 | 3 | 0 | 3 |
| TRIM54 | LINC00598 | 0.689649 | 3 | 0 | 3 |
| TRIM54 | IGFALS | 0.687714 | 4 | 0 | 3 |
| TRIM54 | ISLR2 | 0.675245 | 3 | 0 | 3 |
| TRIM54 | ADCY8 | 0.675079 | 3 | 0 | 3 |
| TRIM54 | ZMYND10 | 0.671756 | 3 | 0 | 3 |
| TRIM54 | NRG1 | 0.666636 | 3 | 0 | 3 |
| TRIM54 | F2 | 0.650607 | 3 | 0 | 3 |
| TRIM54 | CHST8 | 0.650298 | 3 | 0 | 3 |
| TRIM54 | GDF2 | 0.647021 | 3 | 0 | 3 |
| TRIM54 | CPNE6 | 0.64214 | 3 | 0 | 3 |
| TRIM54 | CDH15 | 0.625766 | 4 | 0 | 3 |
| TRIM54 | ENDOV | 0.62409 | 3 | 0 | 3 |
| TRIM54 | SEZ6L2 | 0.614806 | 4 | 0 | 3 |
| TRIM54 | LINC00482 | 0.614744 | 3 | 0 | 3 |
| TRIM54 | SLC22A6 | 0.613579 | 5 | 0 | 3 |
| TRIM54 | PSD | 0.611894 | 4 | 0 | 3 |
| TRIM54 | CACNG2 | 0.610174 | 3 | 0 | 3 |
| TRIM54 | KMT2E-AS1 | 0.605673 | 3 | 0 | 3 |
| TRIM54 | RNF151 | 0.604989 | 4 | 0 | 3 |
For details and further investigation, click here
