URB2

 

Full name: URB2 ribosome biogenesis homolog Alias Symbol: NPA2|NET10
Type: protein-coding gene Cytoband: 1q42.13
Entrez ID: 9816 HGNC ID: HGNC:28967 Ensembl Gene: ENSG00000135763 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of URB2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 URB2 9816 205284_at 1.0459 0.0423
GSE20347 URB2 9816 205284_at 0.5274 0.0000
GSE23400 URB2 9816 205284_at 0.3335 0.0000
GSE26886 URB2 9816 205284_at 0.7654 0.0002
GSE29001 URB2 9816 205284_at 0.5799 0.0002
GSE38129 URB2 9816 205284_at 0.6310 0.0000
GSE45670 URB2 9816 205284_at 0.3985 0.0077
GSE53622 URB2 9816 79623 0.5733 0.0000
GSE53624 URB2 9816 79623 0.9260 0.0000
GSE63941 URB2 9816 205284_at 0.2083 0.4582
GSE77861 URB2 9816 205284_at 0.2920 0.0353
GSE97050 URB2 9816 A_23_P74914 0.4537 0.3026
SRP007169 URB2 9816 RNAseq 0.5452 0.1984
SRP008496 URB2 9816 RNAseq 0.7479 0.0114
SRP064894 URB2 9816 RNAseq 0.2594 0.2553
SRP133303 URB2 9816 RNAseq 0.7214 0.0036
SRP159526 URB2 9816 RNAseq 0.5622 0.1971
SRP193095 URB2 9816 RNAseq 0.6387 0.0000
SRP219564 URB2 9816 RNAseq 0.4620 0.2939
TCGA URB2 9816 RNAseq 0.1081 0.0767

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by URB2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of URB2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 URB2 9816 11 0 19
GSE20123 URB2 9816 11 0 19
GSE43470 URB2 9816 8 1 34
GSE46452 URB2 9816 4 2 53
GSE47630 URB2 9816 15 0 25
GSE54993 URB2 9816 0 6 64
GSE54994 URB2 9816 17 0 36
GSE60625 URB2 9816 0 0 11
GSE74703 URB2 9816 8 1 27
GSE74704 URB2 9816 5 0 15
TCGA URB2 9816 45 3 48

Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.  

 

Somatic mutations of URB2:

 

Generating mutation plots.

 

Highly correlated genes for URB2:

 

Showing top 20/1904 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
URB2DOCK60.803465303
URB2FLVCR10.783345707
URB2LRRC580.781451404
URB2HEATR10.76853512011
URB2LSM14B0.733354303
URB2MMS22L0.731685303
URB2PPP1R16A0.731564303
URB2ISG20L20.73147211011
URB2DHX330.730994707
URB2SSBP40.724399404
URB2PPP1R370.721968303
URB2CDCA20.721149404
URB2CENPF0.7209311010
URB2ANAPC10.715149303
URB2DKC10.709558403
URB2AHCTF10.70938912011
URB2NEK20.7084711010
URB2DNAJC20.70480112011
URB2MCM3AP0.702913303
URB2RAD180.701298403

For details and further investigation, click here