TUBG2

 

Full name: tubulin gamma 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 17q21.2
Entrez ID: 27175 HGNC ID: HGNC:12419 Ensembl Gene: ENSG00000037042 OMIM ID: 605785
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TUBG2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TUBG2 27175 203894_at 0.1515 0.8498
GSE20347 TUBG2 27175 203894_at 0.4856 0.0001
GSE23400 TUBG2 27175 203894_at 0.1870 0.0000
GSE26886 TUBG2 27175 203894_at 0.7985 0.0000
GSE29001 TUBG2 27175 203894_at 0.7268 0.0118
GSE38129 TUBG2 27175 203894_at 0.1840 0.3262
GSE45670 TUBG2 27175 203894_at 0.1526 0.4052
GSE53622 TUBG2 27175 4906 0.3909 0.0000
GSE53624 TUBG2 27175 4906 0.6438 0.0000
GSE63941 TUBG2 27175 203894_at 0.0886 0.8136
GSE77861 TUBG2 27175 203894_at 0.4406 0.0271
GSE97050 TUBG2 27175 A_23_P78014 0.3556 0.2992
SRP007169 TUBG2 27175 RNAseq 1.0849 0.0878
SRP008496 TUBG2 27175 RNAseq 0.8745 0.0320
SRP064894 TUBG2 27175 RNAseq 0.9331 0.0000
SRP133303 TUBG2 27175 RNAseq 0.0193 0.9171
SRP159526 TUBG2 27175 RNAseq 0.7469 0.0715
SRP193095 TUBG2 27175 RNAseq 0.8820 0.0000
SRP219564 TUBG2 27175 RNAseq 0.2112 0.6014
TCGA TUBG2 27175 RNAseq -0.1664 0.0107

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TUBG2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TUBG2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TUBG2 27175 6 2 22
GSE20123 TUBG2 27175 6 2 22
GSE43470 TUBG2 27175 1 2 40
GSE46452 TUBG2 27175 34 0 25
GSE47630 TUBG2 27175 8 1 31
GSE54993 TUBG2 27175 3 4 63
GSE54994 TUBG2 27175 8 5 40
GSE60625 TUBG2 27175 4 0 7
GSE74703 TUBG2 27175 1 1 34
GSE74704 TUBG2 27175 4 1 15
TCGA TUBG2 27175 23 6 67

Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.  


 

Somatic mutations of TUBG2:

 

Generating mutation plots.

 

Highly correlated genes for TUBG2:

 

Showing top 20/1299 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TUBG2VWA10.785407303
TUBG2RASA30.779244303
TUBG2CRTC20.759954303
TUBG2ZFAND30.755542303
TUBG2SGCE0.747781404
TUBG2RRAS0.726329404
TUBG2IQSEC10.722561404
TUBG2EVC0.719361404
TUBG2FLNB0.717364303
TUBG2NCOA60.71411404
TUBG2PLEKHA30.713589404
TUBG2EGFL70.712812504
TUBG2EMILIN20.712374303
TUBG2ALKBH60.711477403
TUBG2AP3D10.707514303
TUBG2CD930.702685303
TUBG2DYNC1LI20.702368303
TUBG2SCNM10.700039303
TUBG2PKIG0.698211404
TUBG2SVEP10.696456404

For details and further investigation, click here