| Full name: tRNA-yW synthesizing protein 1 homolog B | Alias Symbol: RSAFD2|MGC87315|NCRNA00069|LINC00069 | ||
| Type: protein-coding gene | Cytoband: 7q11.22-q11.23 | ||
| Entrez ID: 441250 | HGNC ID: HGNC:33908 | Ensembl Gene: ENSG00000277149 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TYW1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TYW1B | 441250 | 112697 | 0.3965 | 0.0000 | |
| GSE53624 | TYW1B | 441250 | 112697 | 0.4364 | 0.0000 | |
| GSE97050 | TYW1B | 441250 | A_33_P3210986 | 0.1343 | 0.5499 | |
| SRP007169 | TYW1B | 441250 | RNAseq | -1.3474 | 0.0144 | |
| SRP064894 | TYW1B | 441250 | RNAseq | -0.0515 | 0.8200 | |
| SRP133303 | TYW1B | 441250 | RNAseq | -0.1330 | 0.7426 | |
| SRP159526 | TYW1B | 441250 | RNAseq | -0.0174 | 0.9804 | |
| SRP193095 | TYW1B | 441250 | RNAseq | -0.0410 | 0.8508 | |
| SRP219564 | TYW1B | 441250 | RNAseq | 0.0587 | 0.9037 | |
| TCGA | TYW1B | 441250 | RNAseq | 0.1207 | 0.3450 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TYW1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TYW1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TYW1B | 441250 | 12 | 1 | 17 | |
| GSE20123 | TYW1B | 441250 | 11 | 1 | 18 | |
| GSE43470 | TYW1B | 441250 | 3 | 2 | 38 | |
| GSE46452 | TYW1B | 441250 | 12 | 0 | 47 | |
| GSE47630 | TYW1B | 441250 | 7 | 2 | 31 | |
| GSE54993 | TYW1B | 441250 | 2 | 7 | 61 | |
| GSE54994 | TYW1B | 441250 | 13 | 2 | 38 | |
| GSE60625 | TYW1B | 441250 | 0 | 0 | 11 | |
| GSE74703 | TYW1B | 441250 | 3 | 1 | 32 | |
| GSE74704 | TYW1B | 441250 | 7 | 1 | 12 | |
| TCGA | TYW1B | 441250 | 44 | 8 | 44 |
Total number of gains: 114; Total number of losses: 25; Total Number of normals: 349.
Somatic mutations of TYW1B:
Generating mutation plots.
Highly correlated genes for TYW1B:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TYW1B | SPDYE3 | 0.704384 | 3 | 0 | 3 |
| TYW1B | POM121 | 0.693646 | 3 | 0 | 3 |
| TYW1B | DDX55 | 0.688769 | 3 | 0 | 3 |
| TYW1B | USP42 | 0.639634 | 3 | 0 | 3 |
| TYW1B | PILRA | 0.63742 | 3 | 0 | 3 |
| TYW1B | RBM39 | 0.636111 | 3 | 0 | 3 |
| TYW1B | BAZ1B | 0.635189 | 4 | 0 | 4 |
| TYW1B | ESF1 | 0.633792 | 3 | 0 | 3 |
| TYW1B | KNTC1 | 0.627024 | 3 | 0 | 3 |
| TYW1B | PHF14 | 0.622091 | 3 | 0 | 3 |
| TYW1B | MEPCE | 0.611756 | 3 | 0 | 3 |
| TYW1B | ZNF789 | 0.604941 | 4 | 0 | 3 |
| TYW1B | PLOD3 | 0.59855 | 3 | 0 | 3 |
| TYW1B | CCAR1 | 0.595787 | 4 | 0 | 3 |
| TYW1B | DNMT1 | 0.594637 | 3 | 0 | 3 |
| TYW1B | MCM8 | 0.579585 | 3 | 0 | 3 |
| TYW1B | MTIF2 | 0.575985 | 4 | 0 | 3 |
| TYW1B | NOP58 | 0.5638 | 4 | 0 | 4 |
| TYW1B | DNA2 | 0.554141 | 4 | 0 | 3 |
| TYW1B | TOP2A | 0.540651 | 3 | 0 | 3 |
For details and further investigation, click here
