PHF14

 

Full name: PHD finger protein 14 Alias Symbol: KIAA0783
Type: protein-coding gene Cytoband: 7p21.3
Entrez ID: 9678 HGNC ID: HGNC:22203 Ensembl Gene: ENSG00000106443 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of PHF14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PHF14 9678 228095_at 0.2283 0.6423
GSE20347 PHF14 9678 204525_at 0.3531 0.0021
GSE23400 PHF14 9678 204525_at 0.0591 0.0005
GSE26886 PHF14 9678 228095_at 1.4876 0.0000
GSE29001 PHF14 9678 204525_at 0.4179 0.3546
GSE38129 PHF14 9678 204525_at 0.4061 0.0019
GSE45670 PHF14 9678 228095_at 0.6270 0.0002
GSE53622 PHF14 9678 43589 0.8043 0.0000
GSE53624 PHF14 9678 43589 0.6990 0.0000
GSE63941 PHF14 9678 228095_at 0.4585 0.5121
GSE77861 PHF14 9678 228095_at 0.7861 0.0049
GSE97050 PHF14 9678 A_24_P21056 0.5470 0.1913
SRP007169 PHF14 9678 RNAseq 1.1939 0.0015
SRP008496 PHF14 9678 RNAseq 1.5712 0.0000
SRP064894 PHF14 9678 RNAseq 0.9244 0.0000
SRP133303 PHF14 9678 RNAseq 0.3635 0.0128
SRP159526 PHF14 9678 RNAseq 0.8760 0.0027
SRP193095 PHF14 9678 RNAseq 0.2780 0.0113
SRP219564 PHF14 9678 RNAseq 0.5822 0.1214
TCGA PHF14 9678 RNAseq 0.1135 0.0417

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by PHF14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PHF14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PHF14 9678 14 2 14
GSE20123 PHF14 9678 14 2 14
GSE43470 PHF14 9678 5 0 38
GSE46452 PHF14 9678 11 1 47
GSE47630 PHF14 9678 9 1 30
GSE54993 PHF14 9678 0 6 64
GSE54994 PHF14 9678 22 1 30
GSE60625 PHF14 9678 0 0 11
GSE74703 PHF14 9678 5 0 31
GSE74704 PHF14 9678 8 2 10
TCGA PHF14 9678 55 6 35

Total number of gains: 143; Total number of losses: 21; Total Number of normals: 324.  


 

Somatic mutations of PHF14:

 

Generating mutation plots.

 

Highly correlated genes for PHF14:

 

Showing top 20/1575 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PHF14AFAP1L20.743286303
PHF14SNAP470.72192303
PHF14PMS20.714771303
PHF14C18orf540.709013606
PHF14PDE7A0.708301606
PHF14METTL230.708155504
PHF14PDE8A0.708118404
PHF14CDCA20.707882505
PHF14NOP20.704303605
PHF14CASK0.70421404
PHF14SDHAF20.693596303
PHF14GSR0.692813403
PHF14LRRC8A0.692267303
PHF14CRTC20.692144303
PHF14TMEM1380.691954606
PHF14FJX10.691386605
PHF14MCM80.691206807
PHF14CENPO0.690895403
PHF14GORAB0.688078605
PHF14C1orf1310.686837707

For details and further investigation, click here