| Full name: RNA binding motif protein 19 | Alias Symbol: DKFZp586F1023|KIAA0682|Mrd1 | ||
| Type: protein-coding gene | Cytoband: 12q24.13-q24.21 | ||
| Entrez ID: 9904 | HGNC ID: HGNC:29098 | Ensembl Gene: ENSG00000122965 | OMIM ID: 616444 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RBM19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM19 | 9904 | 205115_s_at | 0.8207 | 0.0502 | |
| GSE20347 | RBM19 | 9904 | 206019_at | 0.1013 | 0.4728 | |
| GSE23400 | RBM19 | 9904 | 206019_at | 0.1827 | 0.0038 | |
| GSE26886 | RBM19 | 9904 | 205115_s_at | 0.9805 | 0.0018 | |
| GSE29001 | RBM19 | 9904 | 206019_at | -0.0105 | 0.9691 | |
| GSE38129 | RBM19 | 9904 | 206019_at | 0.1134 | 0.3325 | |
| GSE45670 | RBM19 | 9904 | 206019_at | 0.1667 | 0.2888 | |
| GSE53622 | RBM19 | 9904 | 3956 | 0.6448 | 0.0000 | |
| GSE53624 | RBM19 | 9904 | 3956 | 0.7956 | 0.0000 | |
| GSE63941 | RBM19 | 9904 | 206019_at | 0.4579 | 0.1941 | |
| GSE77861 | RBM19 | 9904 | 205115_s_at | 0.2669 | 0.2761 | |
| GSE97050 | RBM19 | 9904 | A_23_P312344 | 0.0367 | 0.8624 | |
| SRP007169 | RBM19 | 9904 | RNAseq | 1.7007 | 0.0002 | |
| SRP008496 | RBM19 | 9904 | RNAseq | 2.0750 | 0.0000 | |
| SRP064894 | RBM19 | 9904 | RNAseq | 0.3077 | 0.0345 | |
| SRP133303 | RBM19 | 9904 | RNAseq | 0.3236 | 0.0397 | |
| SRP159526 | RBM19 | 9904 | RNAseq | 0.8949 | 0.0092 | |
| SRP193095 | RBM19 | 9904 | RNAseq | 1.1170 | 0.0000 | |
| SRP219564 | RBM19 | 9904 | RNAseq | 0.1346 | 0.5569 | |
| TCGA | RBM19 | 9904 | RNAseq | 0.1716 | 0.0057 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by RBM19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM19 | 9904 | 4 | 3 | 23 | |
| GSE20123 | RBM19 | 9904 | 4 | 3 | 23 | |
| GSE43470 | RBM19 | 9904 | 2 | 0 | 41 | |
| GSE46452 | RBM19 | 9904 | 9 | 1 | 49 | |
| GSE47630 | RBM19 | 9904 | 9 | 3 | 28 | |
| GSE54993 | RBM19 | 9904 | 0 | 5 | 65 | |
| GSE54994 | RBM19 | 9904 | 4 | 2 | 47 | |
| GSE60625 | RBM19 | 9904 | 0 | 0 | 11 | |
| GSE74703 | RBM19 | 9904 | 2 | 0 | 34 | |
| GSE74704 | RBM19 | 9904 | 2 | 2 | 16 | |
| TCGA | RBM19 | 9904 | 22 | 11 | 63 |
Total number of gains: 58; Total number of losses: 30; Total Number of normals: 400.
Somatic mutations of RBM19:
Generating mutation plots.
Highly correlated genes for RBM19:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM19 | XPR1 | 0.659973 | 4 | 0 | 4 |
| RBM19 | ALG1 | 0.653288 | 3 | 0 | 3 |
| RBM19 | DRG2 | 0.650251 | 3 | 0 | 3 |
| RBM19 | SCAND1 | 0.641912 | 4 | 0 | 3 |
| RBM19 | NOB1 | 0.641032 | 4 | 0 | 3 |
| RBM19 | HSD11B2 | 0.640561 | 3 | 0 | 3 |
| RBM19 | CKAP5 | 0.638493 | 5 | 0 | 5 |
| RBM19 | CLCN7 | 0.627533 | 3 | 0 | 3 |
| RBM19 | CHCHD2 | 0.626586 | 3 | 0 | 3 |
| RBM19 | ANKRD39 | 0.625886 | 5 | 0 | 4 |
| RBM19 | CCDC34 | 0.623972 | 4 | 0 | 3 |
| RBM19 | CXXC1 | 0.617272 | 4 | 0 | 4 |
| RBM19 | SCARA3 | 0.616192 | 4 | 0 | 3 |
| RBM19 | PNPT1 | 0.615697 | 5 | 0 | 5 |
| RBM19 | MFAP2 | 0.614375 | 4 | 0 | 4 |
| RBM19 | UBOX5 | 0.614034 | 3 | 0 | 3 |
| RBM19 | ATP6V1C1 | 0.610392 | 5 | 0 | 5 |
| RBM19 | PLAU | 0.608299 | 4 | 0 | 3 |
| RBM19 | RAB6B | 0.604657 | 4 | 0 | 3 |
| RBM19 | POLR2F | 0.60388 | 5 | 0 | 3 |
For details and further investigation, click here
