| Full name: Y-box binding protein 2 | Alias Symbol: MSY2|CSDA3|Contrin | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 51087 | HGNC ID: HGNC:17948 | Ensembl Gene: ENSG00000006047 | OMIM ID: 611447 |
| Drug and gene relationship at DGIdb | |||
Expression of YBX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YBX2 | 51087 | 219704_at | 0.0106 | 0.9879 | |
| GSE20347 | YBX2 | 51087 | 219704_at | 0.1522 | 0.3307 | |
| GSE23400 | YBX2 | 51087 | 219704_at | -0.0599 | 0.1240 | |
| GSE26886 | YBX2 | 51087 | 219704_at | -0.1504 | 0.4409 | |
| GSE29001 | YBX2 | 51087 | 219704_at | -0.1070 | 0.7154 | |
| GSE38129 | YBX2 | 51087 | 219704_at | 0.0116 | 0.9252 | |
| GSE45670 | YBX2 | 51087 | 219704_at | 0.1956 | 0.0783 | |
| GSE53622 | YBX2 | 51087 | 21843 | 0.1201 | 0.3038 | |
| GSE53624 | YBX2 | 51087 | 21843 | 0.2345 | 0.0321 | |
| GSE63941 | YBX2 | 51087 | 219704_at | 1.1143 | 0.0028 | |
| GSE77861 | YBX2 | 51087 | 219704_at | -0.0908 | 0.4585 | |
| GSE97050 | YBX2 | 51087 | A_23_P49865 | -0.3865 | 0.3486 | |
| SRP064894 | YBX2 | 51087 | RNAseq | 0.3566 | 0.4489 | |
| SRP133303 | YBX2 | 51087 | RNAseq | -0.2220 | 0.5279 | |
| SRP159526 | YBX2 | 51087 | RNAseq | 1.9465 | 0.0144 | |
| TCGA | YBX2 | 51087 | RNAseq | 0.1919 | 0.5894 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by YBX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YBX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YBX2 | 51087 | 4 | 2 | 24 | |
| GSE20123 | YBX2 | 51087 | 4 | 3 | 23 | |
| GSE43470 | YBX2 | 51087 | 1 | 4 | 38 | |
| GSE46452 | YBX2 | 51087 | 34 | 1 | 24 | |
| GSE47630 | YBX2 | 51087 | 7 | 1 | 32 | |
| GSE54993 | YBX2 | 51087 | 4 | 3 | 63 | |
| GSE54994 | YBX2 | 51087 | 5 | 8 | 40 | |
| GSE60625 | YBX2 | 51087 | 4 | 0 | 7 | |
| GSE74703 | YBX2 | 51087 | 1 | 2 | 33 | |
| GSE74704 | YBX2 | 51087 | 2 | 1 | 17 | |
| TCGA | YBX2 | 51087 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of YBX2:
Generating mutation plots.
Highly correlated genes for YBX2:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YBX2 | ZNF221 | 0.697778 | 3 | 0 | 3 |
| YBX2 | SEMA3F | 0.674958 | 4 | 0 | 3 |
| YBX2 | ANHX | 0.674288 | 3 | 0 | 3 |
| YBX2 | PCBD1 | 0.663694 | 3 | 0 | 3 |
| YBX2 | UBOX5 | 0.657079 | 4 | 0 | 4 |
| YBX2 | SIRT3 | 0.649829 | 8 | 0 | 6 |
| YBX2 | RANBP3 | 0.647379 | 4 | 0 | 3 |
| YBX2 | NEURL1 | 0.647373 | 3 | 0 | 3 |
| YBX2 | RGS6 | 0.641827 | 4 | 0 | 4 |
| YBX2 | FKBP8 | 0.636002 | 3 | 0 | 3 |
| YBX2 | CALCOCO1 | 0.634799 | 6 | 0 | 5 |
| YBX2 | ANKRD53 | 0.628885 | 4 | 0 | 4 |
| YBX2 | TCTN2 | 0.625149 | 3 | 0 | 3 |
| YBX2 | TNNT3 | 0.624477 | 3 | 0 | 3 |
| YBX2 | NANOG | 0.620852 | 3 | 0 | 3 |
| YBX2 | ENPP3 | 0.617629 | 4 | 0 | 3 |
| YBX2 | TAT | 0.616508 | 4 | 0 | 4 |
| YBX2 | CHST5 | 0.613129 | 5 | 0 | 3 |
| YBX2 | IFT122 | 0.612771 | 4 | 0 | 4 |
| YBX2 | KLK4 | 0.611229 | 4 | 0 | 3 |
For details and further investigation, click here
