| Full name: ubiquinol-cytochrome c reductase complex assembly factor 1 | Alias Symbol: FLJ10850|CBP3|BFZB | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 55245 | HGNC ID: HGNC:15891 | Ensembl Gene: ENSG00000101019 | OMIM ID: 611797 |
| Drug and gene relationship at DGIdb | |||
Expression of UQCC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UQCC1 | 55245 | 217935_s_at | 0.6980 | 0.0674 | |
| GSE20347 | UQCC1 | 55245 | 217935_s_at | 0.4378 | 0.0044 | |
| GSE23400 | UQCC1 | 55245 | 217935_s_at | 0.1599 | 0.0009 | |
| GSE26886 | UQCC1 | 55245 | 217935_s_at | -0.0966 | 0.6150 | |
| GSE29001 | UQCC1 | 55245 | 217935_s_at | 0.3825 | 0.0239 | |
| GSE38129 | UQCC1 | 55245 | 217935_s_at | 0.2076 | 0.0792 | |
| GSE45670 | UQCC1 | 55245 | 217935_s_at | 0.3181 | 0.0251 | |
| GSE53622 | UQCC1 | 55245 | 43403 | 0.7016 | 0.0000 | |
| GSE53624 | UQCC1 | 55245 | 31892 | 0.4983 | 0.0000 | |
| GSE63941 | UQCC1 | 55245 | 217935_s_at | 1.1364 | 0.0231 | |
| GSE77861 | UQCC1 | 55245 | 217935_s_at | 0.1315 | 0.4413 | |
| SRP007169 | UQCC1 | 55245 | RNAseq | 0.7821 | 0.0453 | |
| SRP008496 | UQCC1 | 55245 | RNAseq | 0.3279 | 0.2218 | |
| SRP064894 | UQCC1 | 55245 | RNAseq | 0.5812 | 0.0011 | |
| SRP133303 | UQCC1 | 55245 | RNAseq | 0.5134 | 0.0004 | |
| SRP159526 | UQCC1 | 55245 | RNAseq | 0.1661 | 0.4994 | |
| SRP193095 | UQCC1 | 55245 | RNAseq | 0.1674 | 0.0553 | |
| SRP219564 | UQCC1 | 55245 | RNAseq | 0.4128 | 0.2675 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UQCC1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of UQCC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UQCC1 | 55245 | 16 | 0 | 14 | |
| GSE20123 | UQCC1 | 55245 | 16 | 0 | 14 | |
| GSE43470 | UQCC1 | 55245 | 13 | 0 | 30 | |
| GSE46452 | UQCC1 | 55245 | 29 | 0 | 30 | |
| GSE47630 | UQCC1 | 55245 | 25 | 0 | 15 | |
| GSE54993 | UQCC1 | 55245 | 0 | 17 | 53 | |
| GSE54994 | UQCC1 | 55245 | 24 | 0 | 29 | |
| GSE60625 | UQCC1 | 55245 | 0 | 0 | 11 | |
| GSE74703 | UQCC1 | 55245 | 11 | 0 | 25 | |
| GSE74704 | UQCC1 | 55245 | 11 | 0 | 9 |
Total number of gains: 145; Total number of losses: 17; Total Number of normals: 230.
Somatic mutations of UQCC1:
Generating mutation plots.
Highly correlated genes for UQCC1:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UQCC1 | PIGU | 0.705377 | 6 | 0 | 6 |
| UQCC1 | C16orf91 | 0.690578 | 3 | 0 | 3 |
| UQCC1 | IRF1 | 0.68338 | 3 | 0 | 3 |
| UQCC1 | NFS1 | 0.678588 | 11 | 0 | 10 |
| UQCC1 | FITM2 | 0.672816 | 3 | 0 | 3 |
| UQCC1 | GTPBP4 | 0.661568 | 3 | 0 | 3 |
| UQCC1 | MCM8 | 0.655318 | 4 | 0 | 3 |
| UQCC1 | TSR3 | 0.653628 | 3 | 0 | 3 |
| UQCC1 | PTRH1 | 0.64702 | 3 | 0 | 3 |
| UQCC1 | NANP | 0.644326 | 3 | 0 | 3 |
| UQCC1 | GZF1 | 0.643148 | 5 | 0 | 5 |
| UQCC1 | PYGB | 0.642584 | 3 | 0 | 3 |
| UQCC1 | WDR53 | 0.640761 | 3 | 0 | 3 |
| UQCC1 | RALY | 0.640416 | 8 | 0 | 8 |
| UQCC1 | HAUS6 | 0.635886 | 3 | 0 | 3 |
| UQCC1 | MAD2L2 | 0.633749 | 4 | 0 | 4 |
| UQCC1 | PTPN1 | 0.633239 | 5 | 0 | 4 |
| UQCC1 | DNTTIP1 | 0.632108 | 5 | 0 | 4 |
| UQCC1 | RAE1 | 0.632007 | 9 | 0 | 7 |
| UQCC1 | TMA16 | 0.63063 | 4 | 0 | 3 |
For details and further investigation, click here
