RAE1

 

Full name: ribonucleic acid export 1 Alias Symbol: Mnrp41|Gle2
Type: protein-coding gene Cytoband: 20q13.31
Entrez ID: 8480 HGNC ID: HGNC:9828 Ensembl Gene: ENSG00000101146 OMIM ID: 603343
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RAE1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAE1 8480 201558_at 0.9933 0.0770
GSE20347 RAE1 8480 201558_at 0.6327 0.0000
GSE23400 RAE1 8480 211318_s_at 0.3952 0.0000
GSE26886 RAE1 8480 201558_at 0.5880 0.0094
GSE29001 RAE1 8480 201558_at 0.7634 0.0003
GSE38129 RAE1 8480 201558_at 0.8050 0.0000
GSE45670 RAE1 8480 201558_at 0.5928 0.0002
GSE53622 RAE1 8480 21410 0.5880 0.0000
GSE53624 RAE1 8480 21410 0.7269 0.0000
GSE63941 RAE1 8480 201558_at 1.2746 0.0030
GSE77861 RAE1 8480 201558_at 0.3764 0.0541
GSE97050 RAE1 8480 A_33_P3443165 0.5149 0.1449
SRP007169 RAE1 8480 RNAseq 1.3385 0.0093
SRP008496 RAE1 8480 RNAseq 0.9848 0.0084
SRP064894 RAE1 8480 RNAseq 0.6981 0.0005
SRP133303 RAE1 8480 RNAseq 0.6565 0.0000
SRP159526 RAE1 8480 RNAseq 0.6839 0.0144
SRP193095 RAE1 8480 RNAseq 0.3038 0.0005
SRP219564 RAE1 8480 RNAseq 0.8704 0.0060
TCGA RAE1 8480 RNAseq 0.3173 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by RAE1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RAE1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAE1 8480 14 2 14
GSE20123 RAE1 8480 14 2 14
GSE43470 RAE1 8480 13 0 30
GSE46452 RAE1 8480 29 0 30
GSE47630 RAE1 8480 24 1 15
GSE54993 RAE1 8480 0 18 52
GSE54994 RAE1 8480 29 0 24
GSE60625 RAE1 8480 0 0 11
GSE74703 RAE1 8480 11 0 25
GSE74704 RAE1 8480 11 0 9
TCGA RAE1 8480 43 5 48

Total number of gains: 188; Total number of losses: 28; Total Number of normals: 272.  

 

Somatic mutations of RAE1:

 

Generating mutation plots.

 

Highly correlated genes for RAE1:

 

Showing top 20/1749 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAE1YTHDF10.76929412012
RAE1MRPL380.762739303
RAE1MRGBP0.74709511011
RAE1TTI10.7445671009
RAE1DDX270.73817212012
RAE1CENPBD10.730263505
RAE1CSTF10.72680512010
RAE1MRPS90.722539303
RAE1GINS10.72089312012
RAE1GALC0.719474303
RAE1AURKA0.71922613012
RAE1ADRM10.71821712011
RAE1UBE2C0.71220113011
RAE1CSE1L0.71007713010
RAE1PET1170.707188505
RAE1STAG10.703889303
RAE1TOP2A0.7024311011
RAE1RPN20.70087411010
RAE1LEMD20.700125303
RAE1PSMG30.696925706

For details and further investigation, click here