| Full name: nitric oxide synthase trafficking | Alias Symbol: MGC20702 | ||
| Type: protein-coding gene | Cytoband: 2q24.3 | ||
| Entrez ID: 115677 | HGNC ID: HGNC:20203 | Ensembl Gene: ENSG00000163072 | OMIM ID: 607496 |
| Drug and gene relationship at DGIdb | |||
Expression of NOSTRIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOSTRIN | 115677 | 226992_at | -1.2716 | 0.0220 | |
| GSE26886 | NOSTRIN | 115677 | 226992_at | -0.4241 | 0.0072 | |
| GSE45670 | NOSTRIN | 115677 | 226992_at | -1.2719 | 0.0003 | |
| GSE53622 | NOSTRIN | 115677 | 114062 | -1.4678 | 0.0000 | |
| GSE53624 | NOSTRIN | 115677 | 114062 | -1.5886 | 0.0000 | |
| GSE63941 | NOSTRIN | 115677 | 226992_at | -0.0398 | 0.9437 | |
| GSE77861 | NOSTRIN | 115677 | 226992_at | 0.1690 | 0.2290 | |
| GSE97050 | NOSTRIN | 115677 | A_23_P79360 | -0.1472 | 0.6194 | |
| SRP064894 | NOSTRIN | 115677 | RNAseq | -0.6374 | 0.1001 | |
| SRP133303 | NOSTRIN | 115677 | RNAseq | -1.2095 | 0.0000 | |
| SRP159526 | NOSTRIN | 115677 | RNAseq | -0.6183 | 0.1596 | |
| SRP193095 | NOSTRIN | 115677 | RNAseq | -0.6660 | 0.1002 | |
| SRP219564 | NOSTRIN | 115677 | RNAseq | -1.1834 | 0.0106 | |
| TCGA | NOSTRIN | 115677 | RNAseq | -1.8727 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NOSTRIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOSTRIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOSTRIN | 115677 | 6 | 0 | 24 | |
| GSE20123 | NOSTRIN | 115677 | 6 | 0 | 24 | |
| GSE43470 | NOSTRIN | 115677 | 5 | 1 | 37 | |
| GSE46452 | NOSTRIN | 115677 | 1 | 4 | 54 | |
| GSE47630 | NOSTRIN | 115677 | 5 | 3 | 32 | |
| GSE54993 | NOSTRIN | 115677 | 0 | 5 | 65 | |
| GSE54994 | NOSTRIN | 115677 | 11 | 2 | 40 | |
| GSE60625 | NOSTRIN | 115677 | 0 | 3 | 8 | |
| GSE74703 | NOSTRIN | 115677 | 4 | 1 | 31 | |
| GSE74704 | NOSTRIN | 115677 | 3 | 0 | 17 | |
| TCGA | NOSTRIN | 115677 | 24 | 10 | 62 |
Total number of gains: 65; Total number of losses: 29; Total Number of normals: 394.
Somatic mutations of NOSTRIN:
Generating mutation plots.
Highly correlated genes for NOSTRIN:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOSTRIN | CCL14 | 0.792274 | 3 | 0 | 3 |
| NOSTRIN | TMEM100 | 0.771556 | 6 | 0 | 6 |
| NOSTRIN | MYRIP | 0.757507 | 7 | 0 | 7 |
| NOSTRIN | UTRN | 0.752282 | 4 | 0 | 4 |
| NOSTRIN | CNTN4 | 0.738799 | 3 | 0 | 3 |
| NOSTRIN | ITM2A | 0.736656 | 6 | 0 | 6 |
| NOSTRIN | CFD | 0.735632 | 5 | 0 | 5 |
| NOSTRIN | LINC01082 | 0.731294 | 4 | 0 | 4 |
| NOSTRIN | KL | 0.715926 | 4 | 0 | 4 |
| NOSTRIN | KALRN | 0.71079 | 4 | 0 | 4 |
| NOSTRIN | SEMA3G | 0.707947 | 5 | 0 | 5 |
| NOSTRIN | ACKR1 | 0.707659 | 6 | 0 | 6 |
| NOSTRIN | SLC4A4 | 0.701378 | 5 | 0 | 5 |
| NOSTRIN | PDZRN3 | 0.700905 | 3 | 0 | 3 |
| NOSTRIN | PTGDS | 0.696294 | 6 | 0 | 6 |
| NOSTRIN | RSPO1 | 0.695254 | 4 | 0 | 4 |
| NOSTRIN | AOC3 | 0.694828 | 5 | 0 | 5 |
| NOSTRIN | LIFR | 0.693555 | 5 | 0 | 5 |
| NOSTRIN | RCAN2 | 0.690515 | 7 | 0 | 6 |
| NOSTRIN | KCNAB1 | 0.689539 | 6 | 0 | 5 |
For details and further investigation, click here
