| Full name: VPS51 subunit of GARP complex | Alias Symbol: ANG2|ANG3|FFR | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 738 | HGNC ID: HGNC:1172 | Ensembl Gene: ENSG00000149823 | OMIM ID: 615738 |
Screen Evidence:
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Expression of VPS51:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS51 | 738 | 217969_at | -0.1138 | 0.6758 | |
| GSE20347 | VPS51 | 738 | 217969_at | -0.1828 | 0.3252 | |
| GSE23400 | VPS51 | 738 | 217969_at | -0.0314 | 0.6495 | |
| GSE26886 | VPS51 | 738 | 217969_at | 0.7164 | 0.0001 | |
| GSE29001 | VPS51 | 738 | 217969_at | -0.1053 | 0.7291 | |
| GSE38129 | VPS51 | 738 | 217969_at | -0.2405 | 0.1025 | |
| GSE45670 | VPS51 | 738 | 217969_at | -0.3634 | 0.0011 | |
| GSE63941 | VPS51 | 738 | 217969_at | 0.2823 | 0.6771 | |
| GSE77861 | VPS51 | 738 | 217969_at | 0.0256 | 0.9371 | |
| SRP007169 | VPS51 | 738 | RNAseq | -0.7713 | 0.0149 | |
| SRP008496 | VPS51 | 738 | RNAseq | -0.5990 | 0.0028 | |
| SRP064894 | VPS51 | 738 | RNAseq | -0.1603 | 0.5998 | |
| SRP133303 | VPS51 | 738 | RNAseq | -0.4550 | 0.0177 | |
| SRP159526 | VPS51 | 738 | RNAseq | -0.2921 | 0.0741 | |
| SRP193095 | VPS51 | 738 | RNAseq | -0.3740 | 0.0032 | |
| SRP219564 | VPS51 | 738 | RNAseq | -0.3899 | 0.1506 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of VPS51:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS51 | 738 | 7 | 6 | 17 | |
| GSE20123 | VPS51 | 738 | 7 | 6 | 17 | |
| GSE43470 | VPS51 | 738 | 2 | 3 | 38 | |
| GSE46452 | VPS51 | 738 | 10 | 4 | 45 | |
| GSE47630 | VPS51 | 738 | 5 | 6 | 29 | |
| GSE54993 | VPS51 | 738 | 3 | 0 | 67 | |
| GSE54994 | VPS51 | 738 | 6 | 5 | 42 | |
| GSE60625 | VPS51 | 738 | 0 | 3 | 8 | |
| GSE74703 | VPS51 | 738 | 2 | 1 | 33 | |
| GSE74704 | VPS51 | 738 | 5 | 4 | 11 | |
| TCGA | VPS51 | 738 | 23 | 7 | 66 |
Total number of gains: 70; Total number of losses: 45; Total Number of normals: 373.
Somatic mutations of VPS51:
Generating mutation plots.
Highly correlated genes for VPS51:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS51 | NUDT22 | 0.709544 | 3 | 0 | 3 |
| VPS51 | NME4 | 0.6209 | 3 | 0 | 3 |
| VPS51 | TKT | 0.611942 | 3 | 0 | 3 |
| VPS51 | NFIB | 0.600327 | 3 | 0 | 3 |
| VPS51 | DNAJC4 | 0.595692 | 5 | 0 | 4 |
| VPS51 | RBM4 | 0.591585 | 3 | 0 | 3 |
| VPS51 | POLR2I | 0.584924 | 3 | 0 | 3 |
| VPS51 | AP2A2 | 0.584581 | 3 | 0 | 3 |
| VPS51 | COX8A | 0.582637 | 4 | 0 | 3 |
| VPS51 | TTLL1 | 0.578377 | 4 | 0 | 3 |
| VPS51 | CEP68 | 0.578087 | 4 | 0 | 3 |
| VPS51 | GPR161 | 0.575193 | 4 | 0 | 3 |
| VPS51 | UBXN1 | 0.571375 | 7 | 0 | 5 |
| VPS51 | FKBP2 | 0.562945 | 7 | 0 | 6 |
| VPS51 | HIGD1B | 0.560275 | 3 | 0 | 3 |
| VPS51 | RPS9 | 0.558197 | 5 | 0 | 5 |
| VPS51 | FBLN1 | 0.557286 | 4 | 0 | 4 |
| VPS51 | TCEAL4 | 0.556689 | 3 | 0 | 3 |
| VPS51 | MRPL49 | 0.556155 | 5 | 0 | 3 |
| VPS51 | RPL12 | 0.553679 | 4 | 0 | 3 |
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