| Full name: HIG1 hypoxia inducible domain family member 1B | Alias Symbol: CLST11240|CLST11240-15 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 51751 | HGNC ID: HGNC:24318 | Ensembl Gene: ENSG00000131097 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HIGD1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HIGD1B | 51751 | 219719_at | -0.2553 | 0.2558 | |
| GSE20347 | HIGD1B | 51751 | 219719_at | -0.1683 | 0.0313 | |
| GSE23400 | HIGD1B | 51751 | 219719_at | -0.0059 | 0.8873 | |
| GSE26886 | HIGD1B | 51751 | 219719_at | -0.2665 | 0.0354 | |
| GSE29001 | HIGD1B | 51751 | 219719_at | -0.2794 | 0.0869 | |
| GSE38129 | HIGD1B | 51751 | 219719_at | -0.2280 | 0.0339 | |
| GSE45670 | HIGD1B | 51751 | 219719_at | -0.3557 | 0.0228 | |
| GSE53622 | HIGD1B | 51751 | 91190 | -0.2766 | 0.0014 | |
| GSE53624 | HIGD1B | 51751 | 91190 | -0.4410 | 0.0000 | |
| GSE63941 | HIGD1B | 51751 | 219719_at | 0.2683 | 0.1213 | |
| GSE77861 | HIGD1B | 51751 | 219719_at | 0.0423 | 0.7423 | |
| GSE97050 | HIGD1B | 51751 | A_23_P207354 | -0.0385 | 0.8556 | |
| SRP064894 | HIGD1B | 51751 | RNAseq | 0.1867 | 0.6236 | |
| SRP133303 | HIGD1B | 51751 | RNAseq | -0.9580 | 0.0011 | |
| SRP159526 | HIGD1B | 51751 | RNAseq | -0.6013 | 0.1826 | |
| SRP219564 | HIGD1B | 51751 | RNAseq | -0.9696 | 0.0216 | |
| TCGA | HIGD1B | 51751 | RNAseq | -0.1122 | 0.6443 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HIGD1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HIGD1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HIGD1B | 51751 | 6 | 2 | 22 | |
| GSE20123 | HIGD1B | 51751 | 6 | 2 | 22 | |
| GSE43470 | HIGD1B | 51751 | 1 | 2 | 40 | |
| GSE46452 | HIGD1B | 51751 | 32 | 0 | 27 | |
| GSE47630 | HIGD1B | 51751 | 9 | 0 | 31 | |
| GSE54993 | HIGD1B | 51751 | 3 | 4 | 63 | |
| GSE54994 | HIGD1B | 51751 | 8 | 7 | 38 | |
| GSE60625 | HIGD1B | 51751 | 4 | 0 | 7 | |
| GSE74703 | HIGD1B | 51751 | 1 | 1 | 34 | |
| GSE74704 | HIGD1B | 51751 | 4 | 1 | 15 | |
| TCGA | HIGD1B | 51751 | 27 | 6 | 63 |
Total number of gains: 101; Total number of losses: 25; Total Number of normals: 362.
Somatic mutations of HIGD1B:
Generating mutation plots.
Highly correlated genes for HIGD1B:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HIGD1B | HTR3A | 0.689714 | 3 | 0 | 3 |
| HIGD1B | GPT | 0.684492 | 3 | 0 | 3 |
| HIGD1B | NRG2 | 0.653372 | 5 | 0 | 5 |
| HIGD1B | ACSM2B | 0.64152 | 4 | 0 | 3 |
| HIGD1B | SHOC2 | 0.627549 | 4 | 0 | 3 |
| HIGD1B | ADRA2A | 0.616961 | 6 | 0 | 3 |
| HIGD1B | HRC | 0.616519 | 6 | 0 | 6 |
| HIGD1B | TNNC2 | 0.616032 | 4 | 0 | 3 |
| HIGD1B | DEPTOR | 0.615618 | 4 | 0 | 3 |
| HIGD1B | ECM2 | 0.615575 | 5 | 0 | 5 |
| HIGD1B | SPDEF | 0.611375 | 3 | 0 | 3 |
| HIGD1B | TP53TG5 | 0.610826 | 4 | 0 | 3 |
| HIGD1B | SPNS3 | 0.607377 | 4 | 0 | 4 |
| HIGD1B | SHE | 0.605154 | 4 | 0 | 4 |
| HIGD1B | TM6SF1 | 0.602786 | 5 | 0 | 4 |
| HIGD1B | ADAMTSL4 | 0.601885 | 4 | 0 | 3 |
| HIGD1B | ETV1 | 0.595552 | 3 | 0 | 3 |
| HIGD1B | G6PC | 0.595428 | 3 | 0 | 3 |
| HIGD1B | BUD13 | 0.595088 | 4 | 0 | 3 |
| HIGD1B | SCN2B | 0.594293 | 4 | 0 | 3 |
For details and further investigation, click here
