| Full name: WD repeat domain 34 | Alias Symbol: DIC5|MGC20486|bA216B9.3|FAP133 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 89891 | HGNC ID: HGNC:28296 | Ensembl Gene: ENSG00000119333 | OMIM ID: 613363 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR34 | 89891 | 224715_at | 0.5592 | 0.1885 | |
| GSE26886 | WDR34 | 89891 | 224715_at | 0.6905 | 0.0055 | |
| GSE45670 | WDR34 | 89891 | 224715_at | 0.5991 | 0.0014 | |
| GSE53622 | WDR34 | 89891 | 2974 | 0.1708 | 0.1077 | |
| GSE53624 | WDR34 | 89891 | 2974 | 0.5069 | 0.0000 | |
| GSE63941 | WDR34 | 89891 | 224715_at | 1.8653 | 0.0010 | |
| GSE77861 | WDR34 | 89891 | 224715_at | 0.2141 | 0.3033 | |
| GSE97050 | WDR34 | 89891 | A_23_P20823 | 0.3654 | 0.2515 | |
| SRP007169 | WDR34 | 89891 | RNAseq | 0.6927 | 0.1103 | |
| SRP008496 | WDR34 | 89891 | RNAseq | 0.8000 | 0.0591 | |
| SRP064894 | WDR34 | 89891 | RNAseq | 1.4589 | 0.0007 | |
| SRP133303 | WDR34 | 89891 | RNAseq | 0.2604 | 0.2083 | |
| SRP159526 | WDR34 | 89891 | RNAseq | 0.9104 | 0.0219 | |
| SRP193095 | WDR34 | 89891 | RNAseq | 0.2238 | 0.1179 | |
| SRP219564 | WDR34 | 89891 | RNAseq | 0.5165 | 0.1807 | |
| TCGA | WDR34 | 89891 | RNAseq | 0.2825 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by WDR34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR34 | 89891 | 6 | 9 | 15 | |
| GSE20123 | WDR34 | 89891 | 6 | 9 | 15 | |
| GSE43470 | WDR34 | 89891 | 5 | 8 | 30 | |
| GSE46452 | WDR34 | 89891 | 6 | 13 | 40 | |
| GSE47630 | WDR34 | 89891 | 3 | 16 | 21 | |
| GSE54993 | WDR34 | 89891 | 3 | 3 | 64 | |
| GSE54994 | WDR34 | 89891 | 11 | 8 | 34 | |
| GSE60625 | WDR34 | 89891 | 0 | 0 | 11 | |
| GSE74703 | WDR34 | 89891 | 5 | 6 | 25 | |
| GSE74704 | WDR34 | 89891 | 3 | 7 | 10 | |
| TCGA | WDR34 | 89891 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 103; Total Number of normals: 310.
Somatic mutations of WDR34:
Generating mutation plots.
Highly correlated genes for WDR34:
Showing top 20/586 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR34 | BUB1B | 0.74514 | 4 | 0 | 4 |
| WDR34 | PRKCZ | 0.73303 | 3 | 0 | 3 |
| WDR34 | SLC8B1 | 0.712967 | 3 | 0 | 3 |
| WDR34 | RACGAP1 | 0.710717 | 3 | 0 | 3 |
| WDR34 | DNAJC9 | 0.7077 | 3 | 0 | 3 |
| WDR34 | KNOP1 | 0.706808 | 3 | 0 | 3 |
| WDR34 | ARRDC1 | 0.706225 | 3 | 0 | 3 |
| WDR34 | CCDC34 | 0.689599 | 6 | 0 | 6 |
| WDR34 | CDK18 | 0.683649 | 3 | 0 | 3 |
| WDR34 | SOGA1 | 0.678379 | 4 | 0 | 4 |
| WDR34 | HIP1R | 0.676008 | 3 | 0 | 3 |
| WDR34 | CCNE2 | 0.675843 | 6 | 0 | 6 |
| WDR34 | MTFR2 | 0.673977 | 4 | 0 | 4 |
| WDR34 | CTPS1 | 0.673745 | 3 | 0 | 3 |
| WDR34 | ZWINT | 0.672932 | 6 | 0 | 5 |
| WDR34 | KLC3 | 0.669633 | 3 | 0 | 3 |
| WDR34 | TFAP2C | 0.668029 | 3 | 0 | 3 |
| WDR34 | TRUB2 | 0.667319 | 5 | 0 | 5 |
| WDR34 | ABHD11 | 0.662956 | 3 | 0 | 3 |
| WDR34 | CCNE1 | 0.66133 | 3 | 0 | 3 |
For details and further investigation, click here
