| Full name: arrestin domain containing 1 | Alias Symbol: MGC40555 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 92714 | HGNC ID: HGNC:28633 | Ensembl Gene: ENSG00000197070 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARRDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARRDC1 | 92714 | 226405_s_at | 0.1878 | 0.7924 | |
| GSE26886 | ARRDC1 | 92714 | 226405_s_at | -0.4237 | 0.0366 | |
| GSE45670 | ARRDC1 | 92714 | 226405_s_at | 0.0954 | 0.5508 | |
| GSE53622 | ARRDC1 | 92714 | 1286 | -0.4607 | 0.0003 | |
| GSE53624 | ARRDC1 | 92714 | 1286 | -0.6786 | 0.0000 | |
| GSE63941 | ARRDC1 | 92714 | 226405_s_at | 2.0835 | 0.0004 | |
| GSE77861 | ARRDC1 | 92714 | 226405_s_at | -0.2371 | 0.2201 | |
| GSE97050 | ARRDC1 | 92714 | A_23_P391607 | 0.3024 | 0.5491 | |
| SRP007169 | ARRDC1 | 92714 | RNAseq | -1.9903 | 0.0000 | |
| SRP008496 | ARRDC1 | 92714 | RNAseq | -1.8991 | 0.0000 | |
| SRP064894 | ARRDC1 | 92714 | RNAseq | -0.6049 | 0.0080 | |
| SRP133303 | ARRDC1 | 92714 | RNAseq | -0.6962 | 0.0000 | |
| SRP159526 | ARRDC1 | 92714 | RNAseq | -0.8808 | 0.0004 | |
| SRP193095 | ARRDC1 | 92714 | RNAseq | -0.6386 | 0.0000 | |
| SRP219564 | ARRDC1 | 92714 | RNAseq | -0.3389 | 0.5547 | |
| TCGA | ARRDC1 | 92714 | RNAseq | -0.0957 | 0.1357 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ARRDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARRDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARRDC1 | 92714 | 4 | 7 | 19 | |
| GSE20123 | ARRDC1 | 92714 | 4 | 7 | 19 | |
| GSE43470 | ARRDC1 | 92714 | 3 | 7 | 33 | |
| GSE46452 | ARRDC1 | 92714 | 6 | 13 | 40 | |
| GSE47630 | ARRDC1 | 92714 | 6 | 15 | 19 | |
| GSE54993 | ARRDC1 | 92714 | 3 | 3 | 64 | |
| GSE54994 | ARRDC1 | 92714 | 19 | 3 | 31 | |
| GSE60625 | ARRDC1 | 92714 | 0 | 0 | 11 | |
| GSE74703 | ARRDC1 | 92714 | 3 | 5 | 28 | |
| GSE74704 | ARRDC1 | 92714 | 2 | 5 | 13 | |
| TCGA | ARRDC1 | 92714 | 29 | 23 | 44 |
Total number of gains: 79; Total number of losses: 88; Total Number of normals: 321.
Somatic mutations of ARRDC1:
Generating mutation plots.
Highly correlated genes for ARRDC1:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARRDC1 | FAM110C | 0.710072 | 5 | 0 | 5 |
| ARRDC1 | GRHL2 | 0.706364 | 5 | 0 | 4 |
| ARRDC1 | WDR34 | 0.706225 | 3 | 0 | 3 |
| ARRDC1 | ARAP2 | 0.691801 | 3 | 0 | 3 |
| ARRDC1 | LAD1 | 0.690554 | 8 | 0 | 8 |
| ARRDC1 | SPINT2 | 0.685465 | 5 | 0 | 4 |
| ARRDC1 | F11R | 0.683844 | 4 | 0 | 4 |
| ARRDC1 | MVB12A | 0.683329 | 5 | 0 | 5 |
| ARRDC1 | PRSS8 | 0.68146 | 5 | 0 | 5 |
| ARRDC1 | ZDHHC12 | 0.678975 | 8 | 0 | 8 |
| ARRDC1 | SCNN1A | 0.674789 | 4 | 0 | 4 |
| ARRDC1 | PRKCZ | 0.674241 | 5 | 0 | 5 |
| ARRDC1 | NBEAL2 | 0.673249 | 8 | 0 | 8 |
| ARRDC1 | ST14 | 0.673003 | 7 | 0 | 5 |
| ARRDC1 | PPP2R1A | 0.672021 | 3 | 0 | 3 |
| ARRDC1 | PPP4C | 0.668299 | 5 | 0 | 4 |
| ARRDC1 | SPTBN2 | 0.665628 | 4 | 0 | 4 |
| ARRDC1 | LPAR5 | 0.660383 | 6 | 0 | 5 |
| ARRDC1 | NIPAL1 | 0.657999 | 3 | 0 | 3 |
| ARRDC1 | SUGP1 | 0.657321 | 4 | 0 | 3 |
For details and further investigation, click here
