| Full name: coiled-coil domain containing 34 | Alias Symbol: NY-REN-41|L15|RAMA3 | ||
| Type: protein-coding gene | Cytoband: 11p14.1 | ||
| Entrez ID: 91057 | HGNC ID: HGNC:25079 | Ensembl Gene: ENSG00000109881 | OMIM ID: 612324 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC34 | 91057 | 226287_at | 0.7667 | 0.0921 | |
| GSE26886 | CCDC34 | 91057 | 226287_at | 0.9634 | 0.0020 | |
| GSE45670 | CCDC34 | 91057 | 226287_at | 0.7089 | 0.0013 | |
| GSE53622 | CCDC34 | 91057 | 7934 | 0.5990 | 0.0000 | |
| GSE53624 | CCDC34 | 91057 | 7934 | 0.9484 | 0.0000 | |
| GSE63941 | CCDC34 | 91057 | 226287_at | 1.1199 | 0.0103 | |
| GSE77861 | CCDC34 | 91057 | 226287_at | 0.8398 | 0.0314 | |
| GSE97050 | CCDC34 | 91057 | A_33_P3313796 | 0.9087 | 0.1560 | |
| SRP007169 | CCDC34 | 91057 | RNAseq | 1.5708 | 0.0057 | |
| SRP008496 | CCDC34 | 91057 | RNAseq | 1.5553 | 0.0014 | |
| SRP064894 | CCDC34 | 91057 | RNAseq | 1.1924 | 0.0001 | |
| SRP133303 | CCDC34 | 91057 | RNAseq | 1.3952 | 0.0000 | |
| SRP159526 | CCDC34 | 91057 | RNAseq | 0.8738 | 0.0045 | |
| SRP193095 | CCDC34 | 91057 | RNAseq | 0.0126 | 0.9361 | |
| SRP219564 | CCDC34 | 91057 | RNAseq | 1.1645 | 0.0263 | |
| TCGA | CCDC34 | 91057 | RNAseq | 0.5389 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by CCDC34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC34 | 91057 | 1 | 9 | 20 | |
| GSE20123 | CCDC34 | 91057 | 1 | 8 | 21 | |
| GSE43470 | CCDC34 | 91057 | 1 | 5 | 37 | |
| GSE46452 | CCDC34 | 91057 | 7 | 5 | 47 | |
| GSE47630 | CCDC34 | 91057 | 3 | 10 | 27 | |
| GSE54993 | CCDC34 | 91057 | 3 | 0 | 67 | |
| GSE54994 | CCDC34 | 91057 | 4 | 11 | 38 | |
| GSE60625 | CCDC34 | 91057 | 0 | 0 | 11 | |
| GSE74703 | CCDC34 | 91057 | 1 | 3 | 32 | |
| GSE74704 | CCDC34 | 91057 | 0 | 8 | 12 | |
| TCGA | CCDC34 | 91057 | 13 | 24 | 59 |
Total number of gains: 34; Total number of losses: 83; Total Number of normals: 371.
Somatic mutations of CCDC34:
Generating mutation plots.
Highly correlated genes for CCDC34:
Showing top 20/876 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC34 | RAD51AP1 | 0.734743 | 8 | 0 | 8 |
| CCDC34 | DEPDC1 | 0.73251 | 5 | 0 | 5 |
| CCDC34 | TBC1D7 | 0.729521 | 5 | 0 | 5 |
| CCDC34 | SKA1 | 0.727063 | 6 | 0 | 6 |
| CCDC34 | CDCA8 | 0.724505 | 7 | 0 | 6 |
| CCDC34 | MCM2 | 0.723991 | 8 | 0 | 8 |
| CCDC34 | DLGAP5 | 0.720722 | 8 | 0 | 7 |
| CCDC34 | ERCC6L | 0.718067 | 6 | 0 | 6 |
| CCDC34 | MCM7 | 0.709175 | 8 | 0 | 8 |
| CCDC34 | RACGAP1 | 0.700788 | 5 | 0 | 5 |
| CCDC34 | CEP55 | 0.70067 | 7 | 0 | 6 |
| CCDC34 | GINS1 | 0.698792 | 7 | 0 | 7 |
| CCDC34 | TIMELESS | 0.698105 | 7 | 0 | 6 |
| CCDC34 | FEN1 | 0.696672 | 6 | 0 | 5 |
| CCDC34 | MCM6 | 0.69629 | 7 | 0 | 7 |
| CCDC34 | EMC1 | 0.694583 | 3 | 0 | 3 |
| CCDC34 | BUB1B | 0.694537 | 6 | 0 | 6 |
| CCDC34 | MAD2L1 | 0.694064 | 8 | 0 | 8 |
| CCDC34 | DTL | 0.693899 | 7 | 0 | 7 |
| CCDC34 | KIF4A | 0.691803 | 8 | 0 | 8 |
For details and further investigation, click here
