| Full name: kinesin light chain 3 | Alias Symbol: KLC2L|KNS2B|KLCt | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 147700 | HGNC ID: HGNC:20717 | Ensembl Gene: ENSG00000104892 | OMIM ID: 601334 |
KLC3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05132 | Salmonella infection |
Expression of KLC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLC3 | 147700 | 239853_at | -0.4238 | 0.5862 | |
| GSE26886 | KLC3 | 147700 | 239853_at | -0.0114 | 0.9690 | |
| GSE45670 | KLC3 | 147700 | 239853_at | 0.2101 | 0.5024 | |
| GSE63941 | KLC3 | 147700 | 1552749_a_at | 0.4949 | 0.0066 | |
| GSE77861 | KLC3 | 147700 | 1552749_a_at | 0.0780 | 0.6014 | |
| GSE97050 | KLC3 | 147700 | A_33_P3377750 | 0.1876 | 0.8020 | |
| SRP007169 | KLC3 | 147700 | RNAseq | -1.2135 | 0.0162 | |
| SRP008496 | KLC3 | 147700 | RNAseq | -1.2493 | 0.0000 | |
| SRP064894 | KLC3 | 147700 | RNAseq | -0.0956 | 0.8138 | |
| SRP133303 | KLC3 | 147700 | RNAseq | -0.0329 | 0.9130 | |
| SRP159526 | KLC3 | 147700 | RNAseq | 0.1766 | 0.4468 | |
| SRP219564 | KLC3 | 147700 | RNAseq | -0.6576 | 0.4358 | |
| TCGA | KLC3 | 147700 | RNAseq | 1.4099 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by KLC3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KLC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLC3 | 147700 | 4 | 5 | 21 | |
| GSE20123 | KLC3 | 147700 | 4 | 4 | 22 | |
| GSE43470 | KLC3 | 147700 | 3 | 11 | 29 | |
| GSE46452 | KLC3 | 147700 | 45 | 1 | 13 | |
| GSE47630 | KLC3 | 147700 | 8 | 6 | 26 | |
| GSE54993 | KLC3 | 147700 | 17 | 4 | 49 | |
| GSE54994 | KLC3 | 147700 | 6 | 12 | 35 | |
| GSE60625 | KLC3 | 147700 | 9 | 0 | 2 | |
| GSE74703 | KLC3 | 147700 | 3 | 7 | 26 | |
| GSE74704 | KLC3 | 147700 | 4 | 2 | 14 | |
| TCGA | KLC3 | 147700 | 15 | 16 | 65 |
Total number of gains: 118; Total number of losses: 68; Total Number of normals: 302.
Somatic mutations of KLC3:
Generating mutation plots.
Highly correlated genes for KLC3:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLC3 | TECR | 0.707482 | 3 | 0 | 3 |
| KLC3 | GNA15 | 0.699952 | 4 | 0 | 3 |
| KLC3 | S100A2 | 0.699763 | 4 | 0 | 4 |
| KLC3 | TRAF3IP2 | 0.690559 | 3 | 0 | 3 |
| KLC3 | TUBA4A | 0.685774 | 3 | 0 | 3 |
| KLC3 | DMKN | 0.681139 | 5 | 0 | 5 |
| KLC3 | IRF6 | 0.670748 | 3 | 0 | 3 |
| KLC3 | WDR34 | 0.669633 | 3 | 0 | 3 |
| KLC3 | DSG3 | 0.654895 | 4 | 0 | 3 |
| KLC3 | RHOD | 0.652691 | 4 | 0 | 3 |
| KLC3 | DLX4 | 0.65249 | 3 | 0 | 3 |
| KLC3 | UPP1 | 0.65177 | 4 | 0 | 3 |
| KLC3 | SERPINB5 | 0.65086 | 4 | 0 | 4 |
| KLC3 | IFFO2 | 0.650176 | 3 | 0 | 3 |
| KLC3 | SFN | 0.642592 | 5 | 0 | 3 |
| KLC3 | GPR87 | 0.639403 | 4 | 0 | 3 |
| KLC3 | LPAR5 | 0.639264 | 4 | 0 | 3 |
| KLC3 | C1orf210 | 0.635338 | 3 | 0 | 3 |
| KLC3 | IRX2 | 0.633607 | 3 | 0 | 3 |
| KLC3 | KLF5 | 0.62763 | 3 | 0 | 3 |
For details and further investigation, click here
