| Full name: signal induced proliferation associated 1 like 3 | Alias Symbol: KIAA0545|SPAR3 | ||
| Type: protein-coding gene | Cytoband: 19q13.13-q13.2 | ||
| Entrez ID: 23094 | HGNC ID: HGNC:23801 | Ensembl Gene: ENSG00000105738 | OMIM ID: 616655 |
| Drug and gene relationship at DGIdb | |||
Expression of SIPA1L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SIPA1L3 | 23094 | 37831_at | 0.5766 | 0.1198 | |
| GSE20347 | SIPA1L3 | 23094 | 37831_at | 0.5535 | 0.0003 | |
| GSE23400 | SIPA1L3 | 23094 | 37831_at | 0.2854 | 0.0000 | |
| GSE26886 | SIPA1L3 | 23094 | 37831_at | 0.4542 | 0.0000 | |
| GSE29001 | SIPA1L3 | 23094 | 37831_at | 0.0568 | 0.8107 | |
| GSE38129 | SIPA1L3 | 23094 | 37831_at | 0.7079 | 0.0000 | |
| GSE45670 | SIPA1L3 | 23094 | 37831_at | 0.3093 | 0.0137 | |
| GSE63941 | SIPA1L3 | 23094 | 37831_at | 0.5433 | 0.1410 | |
| GSE77861 | SIPA1L3 | 23094 | 37831_at | 0.4399 | 0.0118 | |
| GSE97050 | SIPA1L3 | 23094 | A_24_P202558 | 0.2878 | 0.3671 | |
| SRP007169 | SIPA1L3 | 23094 | RNAseq | 2.4337 | 0.0002 | |
| SRP008496 | SIPA1L3 | 23094 | RNAseq | 1.9545 | 0.0000 | |
| SRP064894 | SIPA1L3 | 23094 | RNAseq | 0.9054 | 0.0032 | |
| SRP133303 | SIPA1L3 | 23094 | RNAseq | 0.8851 | 0.0002 | |
| SRP159526 | SIPA1L3 | 23094 | RNAseq | 1.5220 | 0.0000 | |
| SRP193095 | SIPA1L3 | 23094 | RNAseq | 0.4506 | 0.0350 | |
| SRP219564 | SIPA1L3 | 23094 | RNAseq | 0.4749 | 0.2461 | |
| TCGA | SIPA1L3 | 23094 | RNAseq | 0.0601 | 0.2994 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SIPA1L3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SIPA1L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SIPA1L3 | 23094 | 7 | 4 | 19 | |
| GSE20123 | SIPA1L3 | 23094 | 7 | 3 | 20 | |
| GSE43470 | SIPA1L3 | 23094 | 4 | 10 | 29 | |
| GSE46452 | SIPA1L3 | 23094 | 47 | 2 | 10 | |
| GSE47630 | SIPA1L3 | 23094 | 10 | 5 | 25 | |
| GSE54993 | SIPA1L3 | 23094 | 17 | 3 | 50 | |
| GSE54994 | SIPA1L3 | 23094 | 6 | 9 | 38 | |
| GSE60625 | SIPA1L3 | 23094 | 9 | 0 | 2 | |
| GSE74703 | SIPA1L3 | 23094 | 4 | 6 | 26 | |
| GSE74704 | SIPA1L3 | 23094 | 7 | 1 | 12 | |
| TCGA | SIPA1L3 | 23094 | 19 | 14 | 63 |
Total number of gains: 137; Total number of losses: 57; Total Number of normals: 294.
Somatic mutations of SIPA1L3:
Generating mutation plots.
Highly correlated genes for SIPA1L3:
Showing top 20/658 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SIPA1L3 | FADS3 | 0.768145 | 3 | 0 | 3 |
| SIPA1L3 | PCED1B | 0.733469 | 3 | 0 | 3 |
| SIPA1L3 | ABL2 | 0.716908 | 3 | 0 | 3 |
| SIPA1L3 | TP53I13 | 0.716145 | 4 | 0 | 3 |
| SIPA1L3 | MSTO1 | 0.713349 | 3 | 0 | 3 |
| SIPA1L3 | C4orf48 | 0.710786 | 4 | 0 | 3 |
| SIPA1L3 | RAI1 | 0.707149 | 3 | 0 | 3 |
| SIPA1L3 | ZDHHC9 | 0.706164 | 3 | 0 | 3 |
| SIPA1L3 | FLVCR1 | 0.702634 | 3 | 0 | 3 |
| SIPA1L3 | NTPCR | 0.696177 | 3 | 0 | 3 |
| SIPA1L3 | DENND4B | 0.694967 | 6 | 0 | 6 |
| SIPA1L3 | COL7A1 | 0.693919 | 7 | 0 | 5 |
| SIPA1L3 | SSBP4 | 0.691551 | 3 | 0 | 3 |
| SIPA1L3 | TMEM9 | 0.691055 | 3 | 0 | 3 |
| SIPA1L3 | NOP58 | 0.687113 | 3 | 0 | 3 |
| SIPA1L3 | IGSF8 | 0.686991 | 4 | 0 | 3 |
| SIPA1L3 | CRTC2 | 0.686138 | 3 | 0 | 3 |
| SIPA1L3 | WDR62 | 0.684314 | 9 | 0 | 7 |
| SIPA1L3 | WDR66 | 0.678725 | 5 | 0 | 4 |
| SIPA1L3 | RNF217 | 0.678541 | 3 | 0 | 3 |
For details and further investigation, click here
