| Full name: survival motor neuron domain containing 1 | Alias Symbol: SPF30|SMNR|TDRD16C | ||
| Type: protein-coding gene | Cytoband: 10q25.2 | ||
| Entrez ID: 10285 | HGNC ID: HGNC:16900 | Ensembl Gene: ENSG00000119953 | OMIM ID: 603519 |
| Drug and gene relationship at DGIdb | |||
Expression of SMNDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMNDC1 | 10285 | 200071_at | 0.5229 | 0.1450 | |
| GSE20347 | SMNDC1 | 10285 | 200071_at | 0.1517 | 0.2583 | |
| GSE23400 | SMNDC1 | 10285 | 200071_at | 0.3870 | 0.0002 | |
| GSE26886 | SMNDC1 | 10285 | 200071_at | 0.2470 | 0.1225 | |
| GSE29001 | SMNDC1 | 10285 | 200071_at | 0.3002 | 0.2030 | |
| GSE38129 | SMNDC1 | 10285 | 200071_at | 0.2324 | 0.0335 | |
| GSE45670 | SMNDC1 | 10285 | 200071_at | 0.1407 | 0.1015 | |
| GSE53622 | SMNDC1 | 10285 | 15740 | -0.1325 | 0.0242 | |
| GSE53624 | SMNDC1 | 10285 | 22191 | 0.2226 | 0.0000 | |
| GSE63941 | SMNDC1 | 10285 | 200071_at | 0.0433 | 0.8967 | |
| GSE77861 | SMNDC1 | 10285 | 200071_at | 0.0824 | 0.6867 | |
| GSE97050 | SMNDC1 | 10285 | A_33_P3219429 | -0.1083 | 0.7646 | |
| SRP007169 | SMNDC1 | 10285 | RNAseq | -0.0813 | 0.8467 | |
| SRP008496 | SMNDC1 | 10285 | RNAseq | 0.0414 | 0.8852 | |
| SRP064894 | SMNDC1 | 10285 | RNAseq | -0.1987 | 0.2570 | |
| SRP133303 | SMNDC1 | 10285 | RNAseq | 0.3066 | 0.0039 | |
| SRP159526 | SMNDC1 | 10285 | RNAseq | -0.1359 | 0.6550 | |
| SRP193095 | SMNDC1 | 10285 | RNAseq | -0.0109 | 0.9068 | |
| SRP219564 | SMNDC1 | 10285 | RNAseq | 0.1362 | 0.5968 | |
| TCGA | SMNDC1 | 10285 | RNAseq | 0.1478 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMNDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMNDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMNDC1 | 10285 | 1 | 10 | 19 | |
| GSE20123 | SMNDC1 | 10285 | 1 | 9 | 20 | |
| GSE43470 | SMNDC1 | 10285 | 0 | 7 | 36 | |
| GSE46452 | SMNDC1 | 10285 | 0 | 11 | 48 | |
| GSE47630 | SMNDC1 | 10285 | 2 | 14 | 24 | |
| GSE54993 | SMNDC1 | 10285 | 8 | 0 | 62 | |
| GSE54994 | SMNDC1 | 10285 | 1 | 10 | 42 | |
| GSE60625 | SMNDC1 | 10285 | 0 | 0 | 11 | |
| GSE74703 | SMNDC1 | 10285 | 0 | 5 | 31 | |
| GSE74704 | SMNDC1 | 10285 | 1 | 4 | 15 | |
| TCGA | SMNDC1 | 10285 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 98; Total Number of normals: 372.
Somatic mutations of SMNDC1:
Generating mutation plots.
Highly correlated genes for SMNDC1:
Showing top 20/658 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMNDC1 | MMP15 | 0.797882 | 3 | 0 | 3 |
| SMNDC1 | DDX20 | 0.763961 | 4 | 0 | 4 |
| SMNDC1 | ZBTB8A | 0.732799 | 3 | 0 | 3 |
| SMNDC1 | WDR89 | 0.711712 | 3 | 0 | 3 |
| SMNDC1 | ZBTB34 | 0.70911 | 3 | 0 | 3 |
| SMNDC1 | TRAPPC6B | 0.705851 | 3 | 0 | 3 |
| SMNDC1 | GMCL1 | 0.703528 | 3 | 0 | 3 |
| SMNDC1 | MASTL | 0.703045 | 5 | 0 | 4 |
| SMNDC1 | MRPS26 | 0.696684 | 3 | 0 | 3 |
| SMNDC1 | TOPORS | 0.693724 | 3 | 0 | 3 |
| SMNDC1 | ITGB8 | 0.692613 | 3 | 0 | 3 |
| SMNDC1 | EFHD2 | 0.692259 | 3 | 0 | 3 |
| SMNDC1 | CHUK | 0.691067 | 11 | 0 | 10 |
| SMNDC1 | KLHL8 | 0.688886 | 3 | 0 | 3 |
| SMNDC1 | FBXW8 | 0.68374 | 3 | 0 | 3 |
| SMNDC1 | TRUB1 | 0.683119 | 7 | 0 | 6 |
| SMNDC1 | DEXI | 0.682788 | 3 | 0 | 3 |
| SMNDC1 | KIAA0895 | 0.679417 | 3 | 0 | 3 |
| SMNDC1 | ROMO1 | 0.677503 | 3 | 0 | 3 |
| SMNDC1 | CASP8AP2 | 0.677448 | 4 | 0 | 4 |
For details and further investigation, click here
