| Full name: lipase G, endothelial type | Alias Symbol: EDL | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 9388 | HGNC ID: HGNC:6623 | Ensembl Gene: ENSG00000101670 | OMIM ID: 603684 |
| Drug and gene relationship at DGIdb | |||
Expression of LIPG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIPG | 9388 | 219181_at | 1.7373 | 0.1403 | |
| GSE20347 | LIPG | 9388 | 219181_at | 0.8829 | 0.0058 | |
| GSE23400 | LIPG | 9388 | 219181_at | 0.6069 | 0.0000 | |
| GSE26886 | LIPG | 9388 | 219181_at | 1.5257 | 0.0021 | |
| GSE29001 | LIPG | 9388 | 219181_at | 1.3424 | 0.0216 | |
| GSE38129 | LIPG | 9388 | 219181_at | 0.9842 | 0.0001 | |
| GSE45670 | LIPG | 9388 | 219181_at | 2.1646 | 0.0027 | |
| GSE53622 | LIPG | 9388 | 796 | 1.3814 | 0.0000 | |
| GSE53624 | LIPG | 9388 | 796 | 1.9145 | 0.0000 | |
| GSE63941 | LIPG | 9388 | 219181_at | -1.3955 | 0.1994 | |
| GSE77861 | LIPG | 9388 | 219181_at | 0.7604 | 0.0367 | |
| GSE97050 | LIPG | 9388 | A_24_P125469 | 0.7181 | 0.1279 | |
| SRP007169 | LIPG | 9388 | RNAseq | 2.1521 | 0.0082 | |
| SRP064894 | LIPG | 9388 | RNAseq | 1.3167 | 0.0020 | |
| SRP133303 | LIPG | 9388 | RNAseq | 0.6171 | 0.0006 | |
| SRP159526 | LIPG | 9388 | RNAseq | 1.6695 | 0.0003 | |
| SRP193095 | LIPG | 9388 | RNAseq | 0.7353 | 0.0001 | |
| SRP219564 | LIPG | 9388 | RNAseq | 1.3856 | 0.0474 | |
| TCGA | LIPG | 9388 | RNAseq | 0.6669 | 0.0023 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by LIPG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIPG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIPG | 9388 | 0 | 10 | 20 | |
| GSE20123 | LIPG | 9388 | 0 | 10 | 20 | |
| GSE43470 | LIPG | 9388 | 0 | 4 | 39 | |
| GSE46452 | LIPG | 9388 | 1 | 26 | 32 | |
| GSE47630 | LIPG | 9388 | 5 | 20 | 15 | |
| GSE54993 | LIPG | 9388 | 9 | 0 | 61 | |
| GSE54994 | LIPG | 9388 | 1 | 17 | 35 | |
| GSE60625 | LIPG | 9388 | 0 | 4 | 7 | |
| GSE74703 | LIPG | 9388 | 0 | 4 | 32 | |
| GSE74704 | LIPG | 9388 | 0 | 6 | 14 | |
| TCGA | LIPG | 9388 | 11 | 42 | 43 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of LIPG:
Generating mutation plots.
Highly correlated genes for LIPG:
Showing top 20/1139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIPG | MKNK1 | 0.777401 | 3 | 0 | 3 |
| LIPG | WIPI1 | 0.743729 | 3 | 0 | 3 |
| LIPG | SERPINB7 | 0.731616 | 3 | 0 | 3 |
| LIPG | CYP27C1 | 0.720709 | 7 | 0 | 6 |
| LIPG | CD276 | 0.717107 | 4 | 0 | 4 |
| LIPG | TRADD | 0.716359 | 4 | 0 | 4 |
| LIPG | ABCB6 | 0.710519 | 3 | 0 | 3 |
| LIPG | SH2B2 | 0.710424 | 3 | 0 | 3 |
| LIPG | WDR54 | 0.708555 | 7 | 0 | 7 |
| LIPG | ALPK2 | 0.700443 | 3 | 0 | 3 |
| LIPG | LILRA3 | 0.699535 | 3 | 0 | 3 |
| LIPG | LIN28A | 0.699424 | 3 | 0 | 3 |
| LIPG | PSPC1 | 0.695239 | 3 | 0 | 3 |
| LIPG | DCBLD1 | 0.691598 | 8 | 0 | 6 |
| LIPG | TTYH3 | 0.682724 | 7 | 0 | 6 |
| LIPG | FAM89A | 0.679808 | 3 | 0 | 3 |
| LIPG | CARD10 | 0.678828 | 6 | 0 | 6 |
| LIPG | LRRC8C | 0.677129 | 3 | 0 | 3 |
| LIPG | SH2D5 | 0.674682 | 6 | 0 | 5 |
| LIPG | SH3PXD2B | 0.673464 | 7 | 0 | 7 |
For details and further investigation, click here
