| Full name: nucleolar protein 6 | Alias Symbol: bA311H10.1|Nrap|FLJ21959|MGC14896|MGC14921|MGC20838|UTP22 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 65083 | HGNC ID: HGNC:19910 | Ensembl Gene: ENSG00000165271 | OMIM ID: 611532 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL6 | 65083 | 218199_s_at | 0.7238 | 0.1573 | |
| GSE20347 | NOL6 | 65083 | 218199_s_at | 0.1142 | 0.4081 | |
| GSE23400 | NOL6 | 65083 | 218199_s_at | 0.2899 | 0.0000 | |
| GSE26886 | NOL6 | 65083 | 218199_s_at | 0.2902 | 0.0481 | |
| GSE29001 | NOL6 | 65083 | 218199_s_at | 0.0644 | 0.7684 | |
| GSE38129 | NOL6 | 65083 | 218199_s_at | 0.2815 | 0.1135 | |
| GSE45670 | NOL6 | 65083 | 218199_s_at | 0.1988 | 0.2751 | |
| GSE53622 | NOL6 | 65083 | 43124 | 0.5234 | 0.0000 | |
| GSE53624 | NOL6 | 65083 | 8012 | 0.3791 | 0.0000 | |
| GSE63941 | NOL6 | 65083 | 218199_s_at | 0.1059 | 0.7628 | |
| GSE77861 | NOL6 | 65083 | 218199_s_at | 0.0815 | 0.5359 | |
| GSE97050 | NOL6 | 65083 | A_24_P38572 | 0.7213 | 0.2434 | |
| SRP007169 | NOL6 | 65083 | RNAseq | 1.1922 | 0.0838 | |
| SRP008496 | NOL6 | 65083 | RNAseq | 0.7940 | 0.0586 | |
| SRP064894 | NOL6 | 65083 | RNAseq | 0.2259 | 0.2467 | |
| SRP133303 | NOL6 | 65083 | RNAseq | 0.0935 | 0.5834 | |
| SRP159526 | NOL6 | 65083 | RNAseq | -0.1342 | 0.7372 | |
| SRP193095 | NOL6 | 65083 | RNAseq | 0.2473 | 0.0541 | |
| SRP219564 | NOL6 | 65083 | RNAseq | 0.6510 | 0.1295 | |
| TCGA | NOL6 | 65083 | RNAseq | 0.1072 | 0.0666 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL6 | 65083 | 3 | 13 | 14 | |
| GSE20123 | NOL6 | 65083 | 3 | 13 | 14 | |
| GSE43470 | NOL6 | 65083 | 3 | 10 | 30 | |
| GSE46452 | NOL6 | 65083 | 7 | 15 | 37 | |
| GSE47630 | NOL6 | 65083 | 1 | 21 | 18 | |
| GSE54993 | NOL6 | 65083 | 6 | 0 | 64 | |
| GSE54994 | NOL6 | 65083 | 7 | 11 | 35 | |
| GSE60625 | NOL6 | 65083 | 0 | 0 | 11 | |
| GSE74703 | NOL6 | 65083 | 2 | 7 | 27 | |
| GSE74704 | NOL6 | 65083 | 0 | 10 | 10 | |
| TCGA | NOL6 | 65083 | 17 | 43 | 36 |
Total number of gains: 49; Total number of losses: 143; Total Number of normals: 296.
Somatic mutations of NOL6:
Generating mutation plots.
Highly correlated genes for NOL6:
Showing top 20/598 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL6 | C8orf76 | 0.729423 | 3 | 0 | 3 |
| NOL6 | PRRC2C | 0.72106 | 3 | 0 | 3 |
| NOL6 | MGAT4B | 0.720713 | 3 | 0 | 3 |
| NOL6 | FANCD2 | 0.715279 | 3 | 0 | 3 |
| NOL6 | PPP4R4 | 0.709498 | 3 | 0 | 3 |
| NOL6 | EFTUD2 | 0.708139 | 4 | 0 | 4 |
| NOL6 | TPM3 | 0.701442 | 5 | 0 | 5 |
| NOL6 | NAGLU | 0.699761 | 3 | 0 | 3 |
| NOL6 | VMA21 | 0.695848 | 3 | 0 | 3 |
| NOL6 | HELLS | 0.68869 | 5 | 0 | 4 |
| NOL6 | BRIP1 | 0.684587 | 3 | 0 | 3 |
| NOL6 | PTPN6 | 0.682162 | 3 | 0 | 3 |
| NOL6 | KTI12 | 0.676357 | 3 | 0 | 3 |
| NOL6 | DHX33 | 0.674007 | 4 | 0 | 4 |
| NOL6 | POM121 | 0.671153 | 3 | 0 | 3 |
| NOL6 | XRCC6 | 0.664196 | 4 | 0 | 3 |
| NOL6 | RNF213 | 0.66223 | 3 | 0 | 3 |
| NOL6 | TRUB1 | 0.661026 | 3 | 0 | 3 |
| NOL6 | ZBTB9 | 0.659326 | 5 | 0 | 5 |
| NOL6 | TRUB2 | 0.658459 | 4 | 0 | 3 |
For details and further investigation, click here
