| Full name: xylosyltransferase 1 | Alias Symbol: XT-I|PXYLT1 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 64131 | HGNC ID: HGNC:15516 | Ensembl Gene: ENSG00000103489 | OMIM ID: 608124 |
| Drug and gene relationship at DGIdb | |||
Expression of XYLT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XYLT1 | 64131 | 213725_x_at | -1.1742 | 0.1028 | |
| GSE20347 | XYLT1 | 64131 | 213725_x_at | -1.2601 | 0.0000 | |
| GSE23400 | XYLT1 | 64131 | 213725_x_at | -0.5901 | 0.0000 | |
| GSE26886 | XYLT1 | 64131 | 213725_x_at | -2.4505 | 0.0000 | |
| GSE29001 | XYLT1 | 64131 | 213725_x_at | -2.1050 | 0.0000 | |
| GSE38129 | XYLT1 | 64131 | 213725_x_at | -0.9352 | 0.0000 | |
| GSE45670 | XYLT1 | 64131 | 213725_x_at | -1.0199 | 0.0146 | |
| GSE53622 | XYLT1 | 64131 | 105350 | -1.0498 | 0.0000 | |
| GSE53624 | XYLT1 | 64131 | 105350 | -1.3953 | 0.0000 | |
| GSE63941 | XYLT1 | 64131 | 213725_x_at | -4.1695 | 0.0032 | |
| GSE77861 | XYLT1 | 64131 | 213725_x_at | -1.3056 | 0.0019 | |
| GSE97050 | XYLT1 | 64131 | A_24_P787897 | -0.1655 | 0.6985 | |
| SRP007169 | XYLT1 | 64131 | RNAseq | -1.6150 | 0.0004 | |
| SRP008496 | XYLT1 | 64131 | RNAseq | -1.3573 | 0.0000 | |
| SRP064894 | XYLT1 | 64131 | RNAseq | -0.5991 | 0.0734 | |
| SRP133303 | XYLT1 | 64131 | RNAseq | -0.4064 | 0.1721 | |
| SRP159526 | XYLT1 | 64131 | RNAseq | -1.1553 | 0.0000 | |
| SRP193095 | XYLT1 | 64131 | RNAseq | -0.9335 | 0.0000 | |
| SRP219564 | XYLT1 | 64131 | RNAseq | -1.1172 | 0.0004 | |
| TCGA | XYLT1 | 64131 | RNAseq | -0.3256 | 0.0162 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by XYLT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XYLT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XYLT1 | 64131 | 5 | 4 | 21 | |
| GSE20123 | XYLT1 | 64131 | 5 | 3 | 22 | |
| GSE43470 | XYLT1 | 64131 | 3 | 3 | 37 | |
| GSE46452 | XYLT1 | 64131 | 38 | 1 | 20 | |
| GSE47630 | XYLT1 | 64131 | 11 | 6 | 23 | |
| GSE54993 | XYLT1 | 64131 | 3 | 5 | 62 | |
| GSE54994 | XYLT1 | 64131 | 3 | 10 | 40 | |
| GSE60625 | XYLT1 | 64131 | 4 | 0 | 7 | |
| GSE74703 | XYLT1 | 64131 | 3 | 2 | 31 | |
| GSE74704 | XYLT1 | 64131 | 2 | 1 | 17 | |
| TCGA | XYLT1 | 64131 | 20 | 12 | 64 |
Total number of gains: 97; Total number of losses: 47; Total Number of normals: 344.
Somatic mutations of XYLT1:
Generating mutation plots.
Highly correlated genes for XYLT1:
Showing top 20/1497 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XYLT1 | DOK6 | 0.810287 | 3 | 0 | 3 |
| XYLT1 | AFF3 | 0.808602 | 3 | 0 | 3 |
| XYLT1 | LRRK2 | 0.746255 | 8 | 0 | 8 |
| XYLT1 | ZNRF1 | 0.741337 | 3 | 0 | 3 |
| XYLT1 | MSRB3 | 0.734294 | 6 | 0 | 6 |
| XYLT1 | CGNL1 | 0.726366 | 8 | 0 | 7 |
| XYLT1 | COG5 | 0.723784 | 3 | 0 | 3 |
| XYLT1 | FNIP2 | 0.719353 | 3 | 0 | 3 |
| XYLT1 | KAT2B | 0.714333 | 12 | 0 | 12 |
| XYLT1 | EIF4E3 | 0.709737 | 7 | 0 | 7 |
| XYLT1 | FIBIN | 0.705026 | 5 | 0 | 4 |
| XYLT1 | SORT1 | 0.704996 | 11 | 0 | 11 |
| XYLT1 | ZFY | 0.703021 | 3 | 0 | 3 |
| XYLT1 | KDM5D | 0.702777 | 4 | 0 | 4 |
| XYLT1 | S100A16 | 0.70185 | 4 | 0 | 4 |
| XYLT1 | S100G | 0.701415 | 3 | 0 | 3 |
| XYLT1 | CYP4V2 | 0.700538 | 4 | 0 | 3 |
| XYLT1 | EPB41L3 | 0.699883 | 12 | 0 | 12 |
| XYLT1 | CNN3 | 0.699097 | 10 | 0 | 9 |
| XYLT1 | DNAJB9 | 0.698392 | 4 | 0 | 4 |
For details and further investigation, click here
