| Full name: yrdC N6-threonylcarbamoyltransferase domain containing | Alias Symbol: FLJ23476|IRIP|SUA5 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 79693 | HGNC ID: HGNC:28905 | Ensembl Gene: ENSG00000196449 | OMIM ID: 612276 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of YRDC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YRDC | 79693 | 218647_s_at | 0.6289 | 0.1120 | |
| GSE20347 | YRDC | 79693 | 218647_s_at | 0.0175 | 0.9171 | |
| GSE23400 | YRDC | 79693 | 218647_s_at | 0.1302 | 0.0161 | |
| GSE26886 | YRDC | 79693 | 218647_s_at | -0.0160 | 0.9522 | |
| GSE29001 | YRDC | 79693 | 218647_s_at | 0.1582 | 0.6337 | |
| GSE38129 | YRDC | 79693 | 218647_s_at | 0.2881 | 0.1183 | |
| GSE45670 | YRDC | 79693 | 218647_s_at | 0.3019 | 0.0286 | |
| GSE53622 | YRDC | 79693 | 15125 | 0.2271 | 0.0035 | |
| GSE53624 | YRDC | 79693 | 15125 | 0.2771 | 0.0007 | |
| GSE63941 | YRDC | 79693 | 218647_s_at | 0.0842 | 0.9020 | |
| GSE77861 | YRDC | 79693 | 218647_s_at | 0.1985 | 0.3122 | |
| GSE97050 | YRDC | 79693 | A_23_P62840 | 0.3831 | 0.2220 | |
| SRP007169 | YRDC | 79693 | RNAseq | -0.1013 | 0.7750 | |
| SRP008496 | YRDC | 79693 | RNAseq | -0.1082 | 0.6570 | |
| SRP064894 | YRDC | 79693 | RNAseq | 0.3394 | 0.0590 | |
| SRP133303 | YRDC | 79693 | RNAseq | 0.3400 | 0.1171 | |
| SRP159526 | YRDC | 79693 | RNAseq | -0.0783 | 0.7910 | |
| SRP193095 | YRDC | 79693 | RNAseq | 0.2659 | 0.0550 | |
| SRP219564 | YRDC | 79693 | RNAseq | 0.5526 | 0.2412 | |
| TCGA | YRDC | 79693 | RNAseq | 0.1544 | 0.0105 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YRDC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YRDC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YRDC | 79693 | 2 | 4 | 24 | |
| GSE20123 | YRDC | 79693 | 2 | 3 | 25 | |
| GSE43470 | YRDC | 79693 | 7 | 3 | 33 | |
| GSE46452 | YRDC | 79693 | 4 | 1 | 54 | |
| GSE47630 | YRDC | 79693 | 8 | 3 | 29 | |
| GSE54993 | YRDC | 79693 | 1 | 1 | 68 | |
| GSE54994 | YRDC | 79693 | 12 | 2 | 39 | |
| GSE60625 | YRDC | 79693 | 0 | 0 | 11 | |
| GSE74703 | YRDC | 79693 | 6 | 2 | 28 | |
| GSE74704 | YRDC | 79693 | 1 | 0 | 19 | |
| TCGA | YRDC | 79693 | 12 | 16 | 68 |
Total number of gains: 55; Total number of losses: 35; Total Number of normals: 398.
Somatic mutations of YRDC:
Generating mutation plots.
Highly correlated genes for YRDC:
Showing top 20/142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YRDC | GRIPAP1 | 0.762371 | 3 | 0 | 3 |
| YRDC | XRCC2 | 0.760267 | 3 | 0 | 3 |
| YRDC | ZDHHC23 | 0.704705 | 3 | 0 | 3 |
| YRDC | MFSD2A | 0.704103 | 5 | 0 | 5 |
| YRDC | CHPF2 | 0.692945 | 3 | 0 | 3 |
| YRDC | BCL2L12 | 0.692349 | 3 | 0 | 3 |
| YRDC | EIF3B | 0.684425 | 4 | 0 | 3 |
| YRDC | ENTPD6 | 0.681447 | 4 | 0 | 4 |
| YRDC | MRPS17 | 0.670205 | 4 | 0 | 3 |
| YRDC | AP1S1 | 0.654536 | 4 | 0 | 3 |
| YRDC | SUV39H2 | 0.641504 | 4 | 0 | 3 |
| YRDC | TTPAL | 0.639829 | 5 | 0 | 3 |
| YRDC | HES5 | 0.636659 | 3 | 0 | 3 |
| YRDC | SH2D5 | 0.629643 | 4 | 0 | 3 |
| YRDC | POLR1A | 0.629451 | 3 | 0 | 3 |
| YRDC | LRR1 | 0.627238 | 4 | 0 | 3 |
| YRDC | BMP8B | 0.624478 | 5 | 0 | 3 |
| YRDC | WRAP73 | 0.62212 | 4 | 0 | 3 |
| YRDC | NOC4L | 0.621149 | 4 | 0 | 3 |
| YRDC | GPR180 | 0.61596 | 5 | 0 | 4 |
For details and further investigation, click here
