| Full name: major facilitator superfamily domain containing 2A | Alias Symbol: FLJ14490 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 84879 | HGNC ID: HGNC:25897 | Ensembl Gene: ENSG00000168389 | OMIM ID: 614397 |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD2A | 84879 | 225316_at | 0.7731 | 0.1348 | |
| GSE26886 | MFSD2A | 84879 | 225316_at | 0.7489 | 0.0216 | |
| GSE45670 | MFSD2A | 84879 | 225316_at | 0.4020 | 0.0971 | |
| GSE53622 | MFSD2A | 84879 | 2569 | 0.4246 | 0.0620 | |
| GSE53624 | MFSD2A | 84879 | 2569 | 0.2713 | 0.0247 | |
| GSE63941 | MFSD2A | 84879 | 225316_at | 0.6675 | 0.0369 | |
| GSE77861 | MFSD2A | 84879 | 225316_at | 0.1543 | 0.3534 | |
| GSE97050 | MFSD2A | 84879 | A_33_P3272231 | 0.6217 | 0.1355 | |
| SRP007169 | MFSD2A | 84879 | RNAseq | -0.1696 | 0.7542 | |
| SRP008496 | MFSD2A | 84879 | RNAseq | -0.7510 | 0.0485 | |
| SRP064894 | MFSD2A | 84879 | RNAseq | -0.3046 | 0.3720 | |
| SRP133303 | MFSD2A | 84879 | RNAseq | 0.3633 | 0.2579 | |
| SRP159526 | MFSD2A | 84879 | RNAseq | 1.5519 | 0.0737 | |
| SRP193095 | MFSD2A | 84879 | RNAseq | 0.2213 | 0.3806 | |
| SRP219564 | MFSD2A | 84879 | RNAseq | 1.1858 | 0.1504 | |
| TCGA | MFSD2A | 84879 | RNAseq | 0.7381 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MFSD2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD2A | 84879 | 3 | 4 | 23 | |
| GSE20123 | MFSD2A | 84879 | 2 | 3 | 25 | |
| GSE43470 | MFSD2A | 84879 | 7 | 2 | 34 | |
| GSE46452 | MFSD2A | 84879 | 4 | 1 | 54 | |
| GSE47630 | MFSD2A | 84879 | 9 | 2 | 29 | |
| GSE54993 | MFSD2A | 84879 | 0 | 1 | 69 | |
| GSE54994 | MFSD2A | 84879 | 13 | 2 | 38 | |
| GSE60625 | MFSD2A | 84879 | 0 | 0 | 11 | |
| GSE74703 | MFSD2A | 84879 | 6 | 1 | 29 | |
| GSE74704 | MFSD2A | 84879 | 1 | 0 | 19 | |
| TCGA | MFSD2A | 84879 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of MFSD2A:
Generating mutation plots.
Highly correlated genes for MFSD2A:
Showing top 20/121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD2A | YRDC | 0.704103 | 5 | 0 | 5 |
| MFSD2A | ZNF593 | 0.663529 | 3 | 0 | 3 |
| MFSD2A | RPA4 | 0.655444 | 4 | 0 | 4 |
| MFSD2A | RRS1 | 0.654999 | 4 | 0 | 3 |
| MFSD2A | RHPN2 | 0.649204 | 3 | 0 | 3 |
| MFSD2A | ADORA2B | 0.637692 | 3 | 0 | 3 |
| MFSD2A | MRPS17 | 0.634878 | 5 | 0 | 4 |
| MFSD2A | POLR1A | 0.632199 | 5 | 0 | 4 |
| MFSD2A | UCN2 | 0.627499 | 6 | 0 | 4 |
| MFSD2A | HSPBAP1 | 0.624342 | 3 | 0 | 3 |
| MFSD2A | IL12RB2 | 0.622607 | 3 | 0 | 3 |
| MFSD2A | LRP8 | 0.619395 | 4 | 0 | 3 |
| MFSD2A | ZDHHC18 | 0.617523 | 5 | 0 | 3 |
| MFSD2A | PC | 0.606644 | 6 | 0 | 4 |
| MFSD2A | COL7A1 | 0.606559 | 6 | 0 | 5 |
| MFSD2A | CCDC86 | 0.602116 | 4 | 0 | 3 |
| MFSD2A | DHX34 | 0.6001 | 4 | 0 | 3 |
| MFSD2A | PIM3 | 0.594846 | 4 | 0 | 3 |
| MFSD2A | TUBA4A | 0.593959 | 4 | 0 | 3 |
| MFSD2A | S100A3 | 0.592817 | 5 | 0 | 3 |
For details and further investigation, click here
