| Full name: zinc finger protein 106 | Alias Symbol: ZNF474|SH3BP3 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 64397 | HGNC ID: HGNC:12886 | Ensembl Gene: ENSG00000103994 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF106:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF106 | 64397 | 217781_s_at | -0.1483 | 0.8586 | |
| GSE20347 | ZNF106 | 64397 | 217781_s_at | 0.0028 | 0.9890 | |
| GSE23400 | ZNF106 | 64397 | 217781_s_at | -0.0266 | 0.7783 | |
| GSE26886 | ZNF106 | 64397 | 217781_s_at | 0.0779 | 0.7730 | |
| GSE29001 | ZNF106 | 64397 | 217781_s_at | -0.1341 | 0.7332 | |
| GSE38129 | ZNF106 | 64397 | 217781_s_at | -0.3939 | 0.0216 | |
| GSE45670 | ZNF106 | 64397 | 217781_s_at | -0.3478 | 0.0036 | |
| GSE53622 | ZNF106 | 64397 | 1782 | -0.5178 | 0.0000 | |
| GSE53624 | ZNF106 | 64397 | 1782 | -0.3271 | 0.0000 | |
| GSE63941 | ZNF106 | 64397 | 222407_s_at | -0.8149 | 0.0118 | |
| GSE77861 | ZNF106 | 64397 | 217781_s_at | 0.1293 | 0.6771 | |
| SRP007169 | ZNF106 | 64397 | RNAseq | 1.0555 | 0.0057 | |
| SRP008496 | ZNF106 | 64397 | RNAseq | 0.9348 | 0.0012 | |
| SRP064894 | ZNF106 | 64397 | RNAseq | -0.0433 | 0.8380 | |
| SRP133303 | ZNF106 | 64397 | RNAseq | -0.0156 | 0.9185 | |
| SRP159526 | ZNF106 | 64397 | RNAseq | -0.3896 | 0.1721 | |
| SRP193095 | ZNF106 | 64397 | RNAseq | 0.1153 | 0.0612 | |
| SRP219564 | ZNF106 | 64397 | RNAseq | -1.0054 | 0.1335 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF106 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ZNF106:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF106 | 64397 | 4 | 5 | 21 | |
| GSE20123 | ZNF106 | 64397 | 4 | 6 | 20 | |
| GSE43470 | ZNF106 | 64397 | 4 | 5 | 34 | |
| GSE46452 | ZNF106 | 64397 | 3 | 7 | 49 | |
| GSE47630 | ZNF106 | 64397 | 8 | 11 | 21 | |
| GSE54993 | ZNF106 | 64397 | 4 | 6 | 60 | |
| GSE54994 | ZNF106 | 64397 | 5 | 7 | 41 | |
| GSE60625 | ZNF106 | 64397 | 4 | 0 | 7 | |
| GSE74703 | ZNF106 | 64397 | 4 | 4 | 28 | |
| GSE74704 | ZNF106 | 64397 | 3 | 3 | 14 | |
| TCGA | ZNF106 | 64397 | 11 | 17 | 68 |
Total number of gains: 54; Total number of losses: 71; Total Number of normals: 363.
Somatic mutations of ZNF106:
Generating mutation plots.
Highly correlated genes for ZNF106:
Showing top 20/393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF106 | DACT3 | 0.680716 | 4 | 0 | 4 |
| ZNF106 | FAM98B | 0.673342 | 5 | 0 | 4 |
| ZNF106 | KLHL42 | 0.66176 | 3 | 0 | 3 |
| ZNF106 | RGMB | 0.659929 | 3 | 0 | 3 |
| ZNF106 | RASSF3 | 0.65679 | 3 | 0 | 3 |
| ZNF106 | MFF | 0.654609 | 4 | 0 | 4 |
| ZNF106 | DENND2A | 0.6536 | 6 | 0 | 5 |
| ZNF106 | ADAMTSL3 | 0.652109 | 4 | 0 | 4 |
| ZNF106 | INPP5A | 0.650922 | 6 | 0 | 5 |
| ZNF106 | CYS1 | 0.644292 | 3 | 0 | 3 |
| ZNF106 | OSR1 | 0.642652 | 3 | 0 | 3 |
| ZNF106 | SMPX | 0.641258 | 4 | 0 | 4 |
| ZNF106 | RFTN1 | 0.637483 | 4 | 0 | 3 |
| ZNF106 | MSANTD4 | 0.635938 | 3 | 0 | 3 |
| ZNF106 | FBXO30 | 0.626087 | 4 | 0 | 4 |
| ZNF106 | INMT | 0.624984 | 4 | 0 | 4 |
| ZNF106 | MYOM1 | 0.623718 | 6 | 0 | 5 |
| ZNF106 | ZNF664 | 0.623012 | 3 | 0 | 3 |
| ZNF106 | PNKD | 0.620754 | 3 | 0 | 3 |
| ZNF106 | PPP3CB | 0.617912 | 8 | 0 | 7 |
For details and further investigation, click here
