| Full name: SEC16 homolog B, endoplasmic reticulum export factor | Alias Symbol: RGPR|PGPR-p117|Sec16S | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 89866 | HGNC ID: HGNC:30301 | Ensembl Gene: ENSG00000120341 | OMIM ID: 612855 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC16B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC16B | 89866 | 1555289_at | -0.1361 | 0.5838 | |
| GSE26886 | SEC16B | 89866 | 228150_at | -0.0685 | 0.8425 | |
| GSE45670 | SEC16B | 89866 | 228150_at | 0.1201 | 0.7910 | |
| GSE63941 | SEC16B | 89866 | 1555289_at | 0.0427 | 0.7992 | |
| GSE77861 | SEC16B | 89866 | 1555289_at | -0.0119 | 0.9256 | |
| GSE97050 | SEC16B | 89866 | A_33_P3418218 | -0.0504 | 0.9157 | |
| SRP064894 | SEC16B | 89866 | RNAseq | -0.2242 | 0.5508 | |
| SRP133303 | SEC16B | 89866 | RNAseq | 1.1440 | 0.0001 | |
| SRP159526 | SEC16B | 89866 | RNAseq | 0.0906 | 0.9222 | |
| SRP193095 | SEC16B | 89866 | RNAseq | -0.0941 | 0.8119 | |
| SRP219564 | SEC16B | 89866 | RNAseq | 0.7808 | 0.2653 | |
| TCGA | SEC16B | 89866 | RNAseq | -0.6189 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SEC16B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SEC16B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC16B | 89866 | 12 | 0 | 18 | |
| GSE20123 | SEC16B | 89866 | 12 | 0 | 18 | |
| GSE43470 | SEC16B | 89866 | 7 | 1 | 35 | |
| GSE46452 | SEC16B | 89866 | 3 | 1 | 55 | |
| GSE47630 | SEC16B | 89866 | 14 | 0 | 26 | |
| GSE54993 | SEC16B | 89866 | 0 | 6 | 64 | |
| GSE54994 | SEC16B | 89866 | 15 | 0 | 38 | |
| GSE60625 | SEC16B | 89866 | 0 | 0 | 11 | |
| GSE74703 | SEC16B | 89866 | 7 | 1 | 28 | |
| GSE74704 | SEC16B | 89866 | 5 | 0 | 15 | |
| TCGA | SEC16B | 89866 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of SEC16B:
Generating mutation plots.
Highly correlated genes for SEC16B:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC16B | LCA5 | 0.792533 | 3 | 0 | 3 |
| SEC16B | ADAM11 | 0.745184 | 3 | 0 | 3 |
| SEC16B | ZNF143 | 0.735461 | 3 | 0 | 3 |
| SEC16B | ITPRIP | 0.721632 | 3 | 0 | 3 |
| SEC16B | ZNF681 | 0.667186 | 3 | 0 | 3 |
| SEC16B | RFX2 | 0.658259 | 4 | 0 | 3 |
| SEC16B | AGFG1 | 0.657394 | 3 | 0 | 3 |
| SEC16B | ETS2 | 0.645514 | 4 | 0 | 3 |
| SEC16B | HLA-DPA1 | 0.633257 | 3 | 0 | 3 |
| SEC16B | CNPPD1 | 0.62534 | 3 | 0 | 3 |
| SEC16B | NFAT5 | 0.615034 | 4 | 0 | 3 |
| SEC16B | USP53 | 0.614353 | 3 | 0 | 3 |
| SEC16B | C11orf54 | 0.608913 | 3 | 0 | 3 |
| SEC16B | PHYHIPL | 0.597814 | 3 | 0 | 3 |
| SEC16B | COPG2 | 0.597713 | 4 | 0 | 3 |
| SEC16B | FGF1 | 0.58871 | 4 | 0 | 3 |
| SEC16B | RHOC | 0.5855 | 5 | 0 | 3 |
| SEC16B | TMEM132C | 0.584819 | 4 | 0 | 3 |
| SEC16B | ZNF547 | 0.563703 | 4 | 0 | 3 |
| SEC16B | RNF208 | 0.541938 | 3 | 0 | 3 |
For details and further investigation, click here
