| Full name: zinc finger protein 280B | Alias Symbol: 5'OY11.1|ZNF632 | ||
| Type: protein-coding gene | Cytoband: 22q11.22 | ||
| Entrez ID: 140883 | HGNC ID: HGNC:23022 | Ensembl Gene: ENSG00000275004 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF280B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF280B | 140883 | 215048_at | -0.0081 | 0.9853 | |
| GSE20347 | ZNF280B | 140883 | 215048_at | -0.1160 | 0.1728 | |
| GSE23400 | ZNF280B | 140883 | 215048_at | -0.0822 | 0.0010 | |
| GSE26886 | ZNF280B | 140883 | 215048_at | -0.2487 | 0.0340 | |
| GSE29001 | ZNF280B | 140883 | 215048_at | -0.2760 | 0.0176 | |
| GSE38129 | ZNF280B | 140883 | 215048_at | -0.1794 | 0.0109 | |
| GSE45670 | ZNF280B | 140883 | 215048_at | 0.0681 | 0.3802 | |
| GSE53622 | ZNF280B | 140883 | 95825 | -0.4507 | 0.0365 | |
| GSE53624 | ZNF280B | 140883 | 95825 | -0.4710 | 0.0054 | |
| GSE63941 | ZNF280B | 140883 | 215048_at | 0.0541 | 0.8286 | |
| GSE77861 | ZNF280B | 140883 | 215048_at | -0.0993 | 0.3721 | |
| SRP133303 | ZNF280B | 140883 | RNAseq | 0.1036 | 0.7195 | |
| SRP159526 | ZNF280B | 140883 | RNAseq | 1.2346 | 0.0760 | |
| TCGA | ZNF280B | 140883 | RNAseq | -0.5363 | 0.1642 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF280B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF280B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF280B | 140883 | 5 | 7 | 18 | |
| GSE20123 | ZNF280B | 140883 | 5 | 6 | 19 | |
| GSE43470 | ZNF280B | 140883 | 3 | 6 | 34 | |
| GSE46452 | ZNF280B | 140883 | 32 | 1 | 26 | |
| GSE47630 | ZNF280B | 140883 | 8 | 5 | 27 | |
| GSE54993 | ZNF280B | 140883 | 3 | 6 | 61 | |
| GSE54994 | ZNF280B | 140883 | 11 | 7 | 35 | |
| GSE60625 | ZNF280B | 140883 | 5 | 0 | 6 | |
| GSE74703 | ZNF280B | 140883 | 3 | 5 | 28 | |
| GSE74704 | ZNF280B | 140883 | 2 | 3 | 15 | |
| TCGA | ZNF280B | 140883 | 27 | 16 | 53 |
Total number of gains: 104; Total number of losses: 62; Total Number of normals: 322.
Somatic mutations of ZNF280B:
Generating mutation plots.
Highly correlated genes for ZNF280B:
Showing top 20/403 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF280B | GPR4 | 0.696056 | 3 | 0 | 3 |
| ZNF280B | TULP2 | 0.686412 | 5 | 0 | 5 |
| ZNF280B | ANKRD44-IT1 | 0.67864 | 3 | 0 | 3 |
| ZNF280B | RXFP3 | 0.670682 | 3 | 0 | 3 |
| ZNF280B | EPS8L3 | 0.653483 | 3 | 0 | 3 |
| ZNF280B | SGSM2 | 0.648594 | 4 | 0 | 3 |
| ZNF280B | OR1G1 | 0.648309 | 4 | 0 | 3 |
| ZNF280B | ZMAT4 | 0.641026 | 4 | 0 | 3 |
| ZNF280B | ABCA4 | 0.637006 | 4 | 0 | 4 |
| ZNF280B | SIRPG | 0.635962 | 4 | 0 | 4 |
| ZNF280B | ADM2 | 0.634877 | 4 | 0 | 4 |
| ZNF280B | USP30-AS1 | 0.634605 | 3 | 0 | 3 |
| ZNF280B | ST8SIA5 | 0.634374 | 3 | 0 | 3 |
| ZNF280B | SFMBT2 | 0.631558 | 3 | 0 | 3 |
| ZNF280B | SLC45A2 | 0.630473 | 4 | 0 | 4 |
| ZNF280B | FABP1 | 0.629187 | 4 | 0 | 3 |
| ZNF280B | MVK | 0.62847 | 6 | 0 | 4 |
| ZNF280B | SCNN1G | 0.628351 | 5 | 0 | 5 |
| ZNF280B | IRS4 | 0.626898 | 4 | 0 | 3 |
| ZNF280B | GJA8 | 0.626173 | 4 | 0 | 3 |
For details and further investigation, click here
