| Full name: small G protein signaling modulator 2 | Alias Symbol: KIAA0397 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 9905 | HGNC ID: HGNC:29026 | Ensembl Gene: ENSG00000141258 | OMIM ID: 611418 |
| Drug and gene relationship at DGIdb | |||
Expression of SGSM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SGSM2 | 9905 | 36129_at | -0.2180 | 0.7174 | |
| GSE20347 | SGSM2 | 9905 | 36129_at | -0.2815 | 0.0707 | |
| GSE23400 | SGSM2 | 9905 | 36129_at | -0.1533 | 0.0016 | |
| GSE26886 | SGSM2 | 9905 | 36129_at | -0.2413 | 0.1429 | |
| GSE29001 | SGSM2 | 9905 | 36129_at | -0.1609 | 0.6817 | |
| GSE38129 | SGSM2 | 9905 | 36129_at | -0.4194 | 0.0004 | |
| GSE45670 | SGSM2 | 9905 | 36129_at | -0.2595 | 0.0493 | |
| GSE53622 | SGSM2 | 9905 | 455 | -0.3394 | 0.0001 | |
| GSE53624 | SGSM2 | 9905 | 455 | -0.2913 | 0.0000 | |
| GSE63941 | SGSM2 | 9905 | 36129_at | -0.1163 | 0.7746 | |
| GSE77861 | SGSM2 | 9905 | 36129_at | -0.0516 | 0.8198 | |
| GSE97050 | SGSM2 | 9905 | A_33_P3333033 | 0.0569 | 0.8465 | |
| SRP007169 | SGSM2 | 9905 | RNAseq | -0.4849 | 0.2880 | |
| SRP008496 | SGSM2 | 9905 | RNAseq | -0.4213 | 0.1592 | |
| SRP064894 | SGSM2 | 9905 | RNAseq | -0.1081 | 0.4301 | |
| SRP133303 | SGSM2 | 9905 | RNAseq | -0.8394 | 0.0000 | |
| SRP159526 | SGSM2 | 9905 | RNAseq | -0.5615 | 0.1500 | |
| SRP193095 | SGSM2 | 9905 | RNAseq | -0.1431 | 0.3724 | |
| SRP219564 | SGSM2 | 9905 | RNAseq | 0.1531 | 0.7829 | |
| TCGA | SGSM2 | 9905 | RNAseq | -0.2998 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SGSM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SGSM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SGSM2 | 9905 | 4 | 2 | 24 | |
| GSE20123 | SGSM2 | 9905 | 4 | 3 | 23 | |
| GSE43470 | SGSM2 | 9905 | 1 | 6 | 36 | |
| GSE46452 | SGSM2 | 9905 | 34 | 1 | 24 | |
| GSE47630 | SGSM2 | 9905 | 7 | 1 | 32 | |
| GSE54993 | SGSM2 | 9905 | 4 | 3 | 63 | |
| GSE54994 | SGSM2 | 9905 | 6 | 9 | 38 | |
| GSE60625 | SGSM2 | 9905 | 4 | 0 | 7 | |
| GSE74703 | SGSM2 | 9905 | 1 | 3 | 32 | |
| GSE74704 | SGSM2 | 9905 | 2 | 1 | 17 | |
| TCGA | SGSM2 | 9905 | 18 | 22 | 56 |
Total number of gains: 85; Total number of losses: 51; Total Number of normals: 352.
Somatic mutations of SGSM2:
Generating mutation plots.
Highly correlated genes for SGSM2:
Showing top 20/72 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SGSM2 | KIAA0825 | 0.652349 | 3 | 0 | 3 |
| SGSM2 | ZNF280B | 0.648594 | 4 | 0 | 3 |
| SGSM2 | RGSL1 | 0.62711 | 3 | 0 | 3 |
| SGSM2 | SMIM14 | 0.594864 | 6 | 0 | 4 |
| SGSM2 | TUBGCP6 | 0.58662 | 5 | 0 | 4 |
| SGSM2 | RPH3AL | 0.583449 | 5 | 0 | 3 |
| SGSM2 | RBM5 | 0.582484 | 11 | 0 | 8 |
| SGSM2 | SH3BP5-AS1 | 0.579359 | 3 | 0 | 3 |
| SGSM2 | PABPN1 | 0.571476 | 4 | 0 | 3 |
| SGSM2 | HUWE1 | 0.569827 | 5 | 0 | 3 |
| SGSM2 | HTR6 | 0.568375 | 4 | 0 | 3 |
| SGSM2 | TTN | 0.565571 | 5 | 0 | 4 |
| SGSM2 | MINK1 | 0.561602 | 6 | 0 | 4 |
| SGSM2 | WAS | 0.561518 | 4 | 0 | 3 |
| SGSM2 | EFNA3 | 0.559885 | 5 | 0 | 3 |
| SGSM2 | CD1C | 0.557491 | 3 | 0 | 3 |
| SGSM2 | HAAO | 0.557326 | 5 | 0 | 3 |
| SGSM2 | TNR | 0.555723 | 4 | 0 | 3 |
| SGSM2 | ATF7 | 0.555645 | 4 | 0 | 3 |
| SGSM2 | BTBD18 | 0.555304 | 5 | 0 | 4 |
For details and further investigation, click here
