| Full name: zinc finger protein 335 | Alias Symbol: bA465L10.2|NIF-1 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 63925 | HGNC ID: HGNC:15807 | Ensembl Gene: ENSG00000198026 | OMIM ID: 610827 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF335:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF335 | 63925 | 221890_at | 0.5436 | 0.0845 | |
| GSE20347 | ZNF335 | 63925 | 221890_at | 0.0978 | 0.2791 | |
| GSE23400 | ZNF335 | 63925 | 221890_at | 0.0685 | 0.1178 | |
| GSE26886 | ZNF335 | 63925 | 221890_at | 0.4029 | 0.0007 | |
| GSE29001 | ZNF335 | 63925 | 78330_at | -0.2168 | 0.1266 | |
| GSE38129 | ZNF335 | 63925 | 221890_at | 0.0051 | 0.9727 | |
| GSE45670 | ZNF335 | 63925 | 221890_at | 0.2650 | 0.0059 | |
| GSE53622 | ZNF335 | 63925 | 11825 | 0.3665 | 0.0000 | |
| GSE53624 | ZNF335 | 63925 | 11825 | 0.3096 | 0.0000 | |
| GSE63941 | ZNF335 | 63925 | 221890_at | 0.4564 | 0.0706 | |
| GSE77861 | ZNF335 | 63925 | 221890_at | 0.2439 | 0.0241 | |
| GSE97050 | ZNF335 | 63925 | A_23_P17382 | 0.4891 | 0.2153 | |
| SRP007169 | ZNF335 | 63925 | RNAseq | -0.1270 | 0.7305 | |
| SRP008496 | ZNF335 | 63925 | RNAseq | -0.3330 | 0.1935 | |
| SRP064894 | ZNF335 | 63925 | RNAseq | 0.2129 | 0.1522 | |
| SRP133303 | ZNF335 | 63925 | RNAseq | 0.0910 | 0.5219 | |
| SRP159526 | ZNF335 | 63925 | RNAseq | 0.1254 | 0.5837 | |
| SRP193095 | ZNF335 | 63925 | RNAseq | 0.2911 | 0.0131 | |
| SRP219564 | ZNF335 | 63925 | RNAseq | -0.0260 | 0.9331 | |
| TCGA | ZNF335 | 63925 | RNAseq | 0.0256 | 0.5970 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF335 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF335:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF335 | 63925 | 14 | 1 | 15 | |
| GSE20123 | ZNF335 | 63925 | 14 | 1 | 15 | |
| GSE43470 | ZNF335 | 63925 | 12 | 1 | 30 | |
| GSE46452 | ZNF335 | 63925 | 29 | 0 | 30 | |
| GSE47630 | ZNF335 | 63925 | 24 | 1 | 15 | |
| GSE54993 | ZNF335 | 63925 | 0 | 17 | 53 | |
| GSE54994 | ZNF335 | 63925 | 25 | 0 | 28 | |
| GSE60625 | ZNF335 | 63925 | 0 | 0 | 11 | |
| GSE74703 | ZNF335 | 63925 | 10 | 1 | 25 | |
| GSE74704 | ZNF335 | 63925 | 10 | 0 | 10 | |
| TCGA | ZNF335 | 63925 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of ZNF335:
Generating mutation plots.
Highly correlated genes for ZNF335:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF335 | CHIT1 | 0.794657 | 3 | 0 | 3 |
| ZNF335 | CPAMD8 | 0.719272 | 3 | 0 | 3 |
| ZNF335 | KLK2 | 0.705171 | 3 | 0 | 3 |
| ZNF335 | IL9R | 0.700484 | 3 | 0 | 3 |
| ZNF335 | TBX6 | 0.691078 | 3 | 0 | 3 |
| ZNF335 | PSG9 | 0.683748 | 3 | 0 | 3 |
| ZNF335 | FOXB1 | 0.675909 | 3 | 0 | 3 |
| ZNF335 | DNLZ | 0.675246 | 3 | 0 | 3 |
| ZNF335 | MSTO1 | 0.67287 | 5 | 0 | 5 |
| ZNF335 | HOXC9 | 0.669808 | 5 | 0 | 5 |
| ZNF335 | CAPN10 | 0.669602 | 4 | 0 | 4 |
| ZNF335 | RHPN1 | 0.668519 | 4 | 0 | 3 |
| ZNF335 | ZMYND15 | 0.664678 | 4 | 0 | 3 |
| ZNF335 | SCYL1 | 0.660346 | 3 | 0 | 3 |
| ZNF335 | ARFGAP1 | 0.659486 | 9 | 0 | 8 |
| ZNF335 | FBRSL1 | 0.655922 | 5 | 0 | 4 |
| ZNF335 | TTC9C | 0.649807 | 3 | 0 | 3 |
| ZNF335 | FSCN3 | 0.646699 | 4 | 0 | 3 |
| ZNF335 | RHOF | 0.645562 | 3 | 0 | 3 |
| ZNF335 | MYPOP | 0.645356 | 4 | 0 | 4 |
For details and further investigation, click here
