RHOF

 

Full name: ras homolog family member F, filopodia associated Alias Symbol: FLJ20247|RIF
Type: protein-coding gene Cytoband: 12q24.31
Entrez ID: 54509 HGNC ID: HGNC:15703 Ensembl Gene: ENSG00000139725 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RHOF:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RHOF 54509 219045_at -0.0210 0.9862
GSE20347 RHOF 54509 219045_at 0.0526 0.8473
GSE23400 RHOF 54509 219045_at -0.1665 0.0382
GSE26886 RHOF 54509 219045_at 0.4796 0.2009
GSE29001 RHOF 54509 219045_at -0.3163 0.2893
GSE38129 RHOF 54509 219045_at -0.1348 0.5076
GSE45670 RHOF 54509 219045_at -0.3604 0.3159
GSE63941 RHOF 54509 219045_at 1.3452 0.2223
GSE77861 RHOF 54509 219045_at 0.1546 0.3069
GSE97050 RHOF 54509 A_24_P104119 0.4431 0.1581
SRP007169 RHOF 54509 RNAseq -2.5465 0.0000
SRP008496 RHOF 54509 RNAseq -2.4308 0.0000
SRP064894 RHOF 54509 RNAseq -2.0633 0.0000
SRP133303 RHOF 54509 RNAseq -0.5667 0.1188
SRP159526 RHOF 54509 RNAseq -1.3238 0.0261
SRP193095 RHOF 54509 RNAseq -1.0788 0.0025
SRP219564 RHOF 54509 RNAseq -2.2467 0.0000
TCGA RHOF 54509 RNAseq -0.3556 0.0407

Upregulated datasets: 0; Downregulated datasets: 6.  


 

Survival by RHOF expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of RHOF:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RHOF 54509 5 4 21
GSE20123 RHOF 54509 5 4 21
GSE43470 RHOF 54509 2 2 39
GSE46452 RHOF 54509 9 1 49
GSE47630 RHOF 54509 9 3 28
GSE54993 RHOF 54509 0 5 65
GSE54994 RHOF 54509 6 7 40
GSE60625 RHOF 54509 0 0 11
GSE74703 RHOF 54509 2 1 33
GSE74704 RHOF 54509 4 2 14
TCGA RHOF 54509 21 10 65

Total number of gains: 63; Total number of losses: 39; Total Number of normals: 386.  


 

Somatic mutations of RHOF:

 

Generating mutation plots.

 

Highly correlated genes for RHOF:

 

Showing top 20/53 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RHOFEML30.748731303
RHOFPLCB30.727202303
RHOFSGSM30.655877303
RHOFSDC10.6497403
RHOFZNF3350.645562303
RHOFPSD40.641341403
RHOFLRRC37A30.636821303
RHOFMAFK0.629636303
RHOFPITPNM10.618182403
RHOFEFNA50.612936303
RHOFHENMT10.606054303
RHOFPON30.602788303
RHOFVCX20.597872303
RHOFNOX50.594563303
RHOFPSAT10.587796303
RHOFBLACAT10.58611303
RHOFB4GALNT30.586027303
RHOFBIN30.585787403
RHOFMAPK150.583976303
RHOFSH3D210.579231504

For details and further investigation, click here