| Full name: zinc finger protein 346 | Alias Symbol: JAZ|Zfp346 | ||
| Type: protein-coding gene | Cytoband: 5q35.2 | ||
| Entrez ID: 23567 | HGNC ID: HGNC:16403 | Ensembl Gene: ENSG00000113761 | OMIM ID: 605308 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF346:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF346 | 23567 | 222884_at | -0.0867 | 0.7120 | |
| GSE26886 | ZNF346 | 23567 | 222884_at | -0.2130 | 0.2708 | |
| GSE45670 | ZNF346 | 23567 | 236267_at | -0.1825 | 0.1319 | |
| GSE53622 | ZNF346 | 23567 | 141929 | -0.1132 | 0.1263 | |
| GSE53624 | ZNF346 | 23567 | 141929 | 0.0366 | 0.6202 | |
| GSE63941 | ZNF346 | 23567 | 222884_at | 0.0064 | 0.9883 | |
| GSE77861 | ZNF346 | 23567 | 222884_at | 0.0047 | 0.9828 | |
| GSE97050 | ZNF346 | 23567 | A_33_P3241482 | -0.2073 | 0.3454 | |
| SRP007169 | ZNF346 | 23567 | RNAseq | -1.0445 | 0.0029 | |
| SRP008496 | ZNF346 | 23567 | RNAseq | -0.9489 | 0.0000 | |
| SRP064894 | ZNF346 | 23567 | RNAseq | -0.0725 | 0.5599 | |
| SRP133303 | ZNF346 | 23567 | RNAseq | -0.1842 | 0.1189 | |
| SRP159526 | ZNF346 | 23567 | RNAseq | -0.0062 | 0.9839 | |
| SRP193095 | ZNF346 | 23567 | RNAseq | -0.0940 | 0.4262 | |
| SRP219564 | ZNF346 | 23567 | RNAseq | 0.1800 | 0.5755 | |
| TCGA | ZNF346 | 23567 | RNAseq | -0.1077 | 0.0724 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF346 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF346:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF346 | 23567 | 2 | 13 | 15 | |
| GSE20123 | ZNF346 | 23567 | 2 | 13 | 15 | |
| GSE43470 | ZNF346 | 23567 | 1 | 11 | 31 | |
| GSE46452 | ZNF346 | 23567 | 0 | 27 | 32 | |
| GSE47630 | ZNF346 | 23567 | 0 | 20 | 20 | |
| GSE54993 | ZNF346 | 23567 | 10 | 2 | 58 | |
| GSE54994 | ZNF346 | 23567 | 2 | 17 | 34 | |
| GSE60625 | ZNF346 | 23567 | 1 | 0 | 10 | |
| GSE74703 | ZNF346 | 23567 | 1 | 7 | 28 | |
| GSE74704 | ZNF346 | 23567 | 1 | 6 | 13 | |
| TCGA | ZNF346 | 23567 | 7 | 35 | 54 |
Total number of gains: 27; Total number of losses: 151; Total Number of normals: 310.
Somatic mutations of ZNF346:
Generating mutation plots.
Highly correlated genes for ZNF346:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF346 | GPCPD1 | 0.775722 | 3 | 0 | 3 |
| ZNF346 | C5orf24 | 0.729034 | 3 | 0 | 3 |
| ZNF346 | FYTTD1 | 0.706112 | 3 | 0 | 3 |
| ZNF346 | ANKHD1 | 0.705024 | 3 | 0 | 3 |
| ZNF346 | NFIB | 0.684838 | 3 | 0 | 3 |
| ZNF346 | CERS4 | 0.678026 | 3 | 0 | 3 |
| ZNF346 | OGG1 | 0.677982 | 3 | 0 | 3 |
| ZNF346 | KCNJ5 | 0.677479 | 3 | 0 | 3 |
| ZNF346 | N4BP2L2 | 0.673079 | 3 | 0 | 3 |
| ZNF346 | SMARCC2 | 0.670709 | 4 | 0 | 4 |
| ZNF346 | WSB1 | 0.660393 | 4 | 0 | 3 |
| ZNF346 | MED7 | 0.660345 | 4 | 0 | 3 |
| ZNF346 | AREG | 0.659955 | 3 | 0 | 3 |
| ZNF346 | UBR4 | 0.654255 | 4 | 0 | 3 |
| ZNF346 | MAPK9 | 0.649439 | 4 | 0 | 3 |
| ZNF346 | NDUFA2 | 0.647304 | 4 | 0 | 3 |
| ZNF346 | ZSWIM5 | 0.641747 | 3 | 0 | 3 |
| ZNF346 | PDK2 | 0.641006 | 4 | 0 | 3 |
| ZNF346 | WWC2 | 0.634652 | 3 | 0 | 3 |
| ZNF346 | BSDC1 | 0.625748 | 4 | 0 | 3 |
For details and further investigation, click here
