| Full name: WW and C2 domain containing 2 | Alias Symbol: BOMB|FLJ22029 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 80014 | HGNC ID: HGNC:24148 | Ensembl Gene: ENSG00000151718 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WWC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WWC2 | 80014 | 237656_at | -0.2033 | 0.4812 | |
| GSE26886 | WWC2 | 80014 | 237656_at | -0.2313 | 0.0469 | |
| GSE45670 | WWC2 | 80014 | 237656_at | -0.2363 | 0.0282 | |
| GSE53622 | WWC2 | 80014 | 47602 | 0.0168 | 0.9093 | |
| GSE53624 | WWC2 | 80014 | 47602 | -0.2315 | 0.0764 | |
| GSE63941 | WWC2 | 80014 | 237656_at | 0.1607 | 0.3597 | |
| GSE77861 | WWC2 | 80014 | 237656_at | -0.1124 | 0.1918 | |
| GSE97050 | WWC2 | 80014 | A_33_P3283122 | -0.5977 | 0.2015 | |
| SRP007169 | WWC2 | 80014 | RNAseq | -0.0512 | 0.9352 | |
| SRP008496 | WWC2 | 80014 | RNAseq | 0.1620 | 0.6903 | |
| SRP064894 | WWC2 | 80014 | RNAseq | -0.3677 | 0.2117 | |
| SRP133303 | WWC2 | 80014 | RNAseq | 0.2952 | 0.2312 | |
| SRP159526 | WWC2 | 80014 | RNAseq | -0.3197 | 0.2795 | |
| SRP193095 | WWC2 | 80014 | RNAseq | -0.0828 | 0.6188 | |
| SRP219564 | WWC2 | 80014 | RNAseq | -0.6957 | 0.0973 | |
| TCGA | WWC2 | 80014 | RNAseq | -0.2836 | 0.0025 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WWC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WWC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WWC2 | 80014 | 2 | 11 | 17 | |
| GSE20123 | WWC2 | 80014 | 2 | 11 | 17 | |
| GSE43470 | WWC2 | 80014 | 0 | 13 | 30 | |
| GSE46452 | WWC2 | 80014 | 1 | 36 | 22 | |
| GSE47630 | WWC2 | 80014 | 0 | 22 | 18 | |
| GSE54993 | WWC2 | 80014 | 10 | 0 | 60 | |
| GSE54994 | WWC2 | 80014 | 2 | 12 | 39 | |
| GSE60625 | WWC2 | 80014 | 0 | 0 | 11 | |
| GSE74703 | WWC2 | 80014 | 0 | 10 | 26 | |
| GSE74704 | WWC2 | 80014 | 1 | 5 | 14 | |
| TCGA | WWC2 | 80014 | 11 | 34 | 51 |
Total number of gains: 29; Total number of losses: 154; Total Number of normals: 305.
Somatic mutations of WWC2:
Generating mutation plots.
Highly correlated genes for WWC2:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WWC2 | TICAM1 | 0.672375 | 3 | 0 | 3 |
| WWC2 | ZNF346 | 0.634652 | 3 | 0 | 3 |
| WWC2 | MSRB3 | 0.616246 | 3 | 0 | 3 |
| WWC2 | BLOC1S1 | 0.616118 | 3 | 0 | 3 |
| WWC2 | GADD45B | 0.615486 | 4 | 0 | 3 |
| WWC2 | GRHPR | 0.612745 | 3 | 0 | 3 |
| WWC2 | FAM83D | 0.612084 | 3 | 0 | 3 |
| WWC2 | PLK3 | 0.610742 | 4 | 0 | 4 |
| WWC2 | ST3GAL3 | 0.610434 | 3 | 0 | 3 |
| WWC2 | MPV17L | 0.60948 | 3 | 0 | 3 |
| WWC2 | PAX1 | 0.607439 | 3 | 0 | 3 |
| WWC2 | ZBTB43 | 0.60469 | 3 | 0 | 3 |
| WWC2 | FBXW7 | 0.602919 | 4 | 0 | 3 |
| WWC2 | LRRFIP2 | 0.601015 | 4 | 0 | 4 |
| WWC2 | AMBRA1 | 0.599645 | 3 | 0 | 3 |
| WWC2 | ASAP3 | 0.599562 | 3 | 0 | 3 |
| WWC2 | ZNF619 | 0.597085 | 3 | 0 | 3 |
| WWC2 | VPS13D | 0.595487 | 3 | 0 | 3 |
| WWC2 | CTTNBP2NL | 0.594583 | 3 | 0 | 3 |
| WWC2 | RASGEF1B | 0.594278 | 5 | 0 | 3 |
For details and further investigation, click here
