| Full name: syntaxin 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 10228 | HGNC ID: HGNC:11441 | Ensembl Gene: ENSG00000135823 | OMIM ID: 603944 |
| Drug and gene relationship at DGIdb | |||
Expression of STX6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX6 | 10228 | 212799_at | 0.4535 | 0.3835 | |
| GSE20347 | STX6 | 10228 | 212799_at | -0.2898 | 0.0193 | |
| GSE23400 | STX6 | 10228 | 212799_at | 0.1240 | 0.0887 | |
| GSE26886 | STX6 | 10228 | 212799_at | -0.4553 | 0.0099 | |
| GSE29001 | STX6 | 10228 | 212799_at | 0.1204 | 0.5542 | |
| GSE38129 | STX6 | 10228 | 212799_at | 0.0661 | 0.6996 | |
| GSE45670 | STX6 | 10228 | 212799_at | 0.1899 | 0.0769 | |
| GSE53622 | STX6 | 10228 | 47391 | -0.0530 | 0.5527 | |
| GSE53624 | STX6 | 10228 | 47391 | -0.1598 | 0.0205 | |
| GSE63941 | STX6 | 10228 | 212799_at | -0.4309 | 0.2013 | |
| GSE77861 | STX6 | 10228 | 212799_at | -0.1187 | 0.5711 | |
| GSE97050 | STX6 | 10228 | A_24_P639505 | 0.1565 | 0.5000 | |
| SRP007169 | STX6 | 10228 | RNAseq | -0.2203 | 0.5553 | |
| SRP008496 | STX6 | 10228 | RNAseq | -0.0631 | 0.7904 | |
| SRP064894 | STX6 | 10228 | RNAseq | 0.2584 | 0.0836 | |
| SRP133303 | STX6 | 10228 | RNAseq | 0.3153 | 0.0223 | |
| SRP159526 | STX6 | 10228 | RNAseq | 0.1925 | 0.4690 | |
| SRP193095 | STX6 | 10228 | RNAseq | 0.0259 | 0.8383 | |
| SRP219564 | STX6 | 10228 | RNAseq | 0.4119 | 0.3554 | |
| TCGA | STX6 | 10228 | RNAseq | 0.3660 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX6 | 10228 | 12 | 0 | 18 | |
| GSE20123 | STX6 | 10228 | 12 | 0 | 18 | |
| GSE43470 | STX6 | 10228 | 7 | 1 | 35 | |
| GSE46452 | STX6 | 10228 | 3 | 1 | 55 | |
| GSE47630 | STX6 | 10228 | 14 | 0 | 26 | |
| GSE54993 | STX6 | 10228 | 0 | 6 | 64 | |
| GSE54994 | STX6 | 10228 | 15 | 0 | 38 | |
| GSE60625 | STX6 | 10228 | 0 | 0 | 11 | |
| GSE74703 | STX6 | 10228 | 7 | 1 | 28 | |
| GSE74704 | STX6 | 10228 | 5 | 0 | 15 | |
| TCGA | STX6 | 10228 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of STX6:
Generating mutation plots.
Highly correlated genes for STX6:
Showing top 20/512 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX6 | PUSL1 | 0.771178 | 3 | 0 | 3 |
| STX6 | VPS45 | 0.759985 | 3 | 0 | 3 |
| STX6 | PDCD6 | 0.757717 | 3 | 0 | 3 |
| STX6 | ZNF557 | 0.734777 | 3 | 0 | 3 |
| STX6 | MDM2 | 0.734366 | 4 | 0 | 4 |
| STX6 | CCDC6 | 0.730934 | 4 | 0 | 4 |
| STX6 | EIF2S2 | 0.727666 | 3 | 0 | 3 |
| STX6 | CHMP4B | 0.726611 | 3 | 0 | 3 |
| STX6 | RPP40 | 0.724291 | 4 | 0 | 3 |
| STX6 | ZNF700 | 0.723819 | 3 | 0 | 3 |
| STX6 | HERC4 | 0.723332 | 4 | 0 | 3 |
| STX6 | MTCH2 | 0.721327 | 4 | 0 | 4 |
| STX6 | GPCPD1 | 0.714175 | 3 | 0 | 3 |
| STX6 | FBXW2 | 0.713696 | 4 | 0 | 3 |
| STX6 | SPIN4 | 0.708072 | 4 | 0 | 4 |
| STX6 | TLE4 | 0.705584 | 3 | 0 | 3 |
| STX6 | LY75 | 0.699823 | 4 | 0 | 3 |
| STX6 | TMEM161B | 0.695052 | 3 | 0 | 3 |
| STX6 | SHISA5 | 0.692902 | 3 | 0 | 3 |
| STX6 | TCF19 | 0.688566 | 3 | 0 | 3 |
For details and further investigation, click here
