| Full name: zinc finger protein 688 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 146542 | HGNC ID: HGNC:30489 | Ensembl Gene: ENSG00000229809 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF688:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF688 | 146542 | 213527_s_at | -0.1973 | 0.5217 | |
| GSE20347 | ZNF688 | 146542 | 213527_s_at | -0.0513 | 0.7327 | |
| GSE23400 | ZNF688 | 146542 | 213527_s_at | -0.0108 | 0.8590 | |
| GSE26886 | ZNF688 | 146542 | 213527_s_at | 0.8099 | 0.0000 | |
| GSE29001 | ZNF688 | 146542 | 213527_s_at | -0.0108 | 0.9545 | |
| GSE38129 | ZNF688 | 146542 | 213527_s_at | -0.0835 | 0.5698 | |
| GSE45670 | ZNF688 | 146542 | 213527_s_at | 0.1367 | 0.1506 | |
| GSE53622 | ZNF688 | 146542 | 45142 | 0.0838 | 0.2147 | |
| GSE53624 | ZNF688 | 146542 | 45142 | 0.2541 | 0.0001 | |
| GSE63941 | ZNF688 | 146542 | 213527_s_at | -0.3162 | 0.4972 | |
| GSE77861 | ZNF688 | 146542 | 213529_at | -0.0885 | 0.6527 | |
| GSE97050 | ZNF688 | 146542 | A_23_P141044 | 0.1464 | 0.6428 | |
| SRP007169 | ZNF688 | 146542 | RNAseq | -1.1224 | 0.0381 | |
| SRP064894 | ZNF688 | 146542 | RNAseq | 0.6149 | 0.1178 | |
| SRP133303 | ZNF688 | 146542 | RNAseq | 0.2403 | 0.1651 | |
| SRP159526 | ZNF688 | 146542 | RNAseq | 0.0262 | 0.9297 | |
| SRP193095 | ZNF688 | 146542 | RNAseq | -0.2247 | 0.1096 | |
| SRP219564 | ZNF688 | 146542 | RNAseq | 0.2296 | 0.5606 | |
| TCGA | ZNF688 | 146542 | RNAseq | -0.0751 | 0.3262 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF688 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF688:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF688 | 146542 | 5 | 5 | 20 | |
| GSE20123 | ZNF688 | 146542 | 5 | 4 | 21 | |
| GSE43470 | ZNF688 | 146542 | 3 | 3 | 37 | |
| GSE46452 | ZNF688 | 146542 | 38 | 1 | 20 | |
| GSE47630 | ZNF688 | 146542 | 11 | 7 | 22 | |
| GSE54993 | ZNF688 | 146542 | 2 | 5 | 63 | |
| GSE54994 | ZNF688 | 146542 | 5 | 9 | 39 | |
| GSE60625 | ZNF688 | 146542 | 4 | 0 | 7 | |
| GSE74703 | ZNF688 | 146542 | 3 | 2 | 31 | |
| GSE74704 | ZNF688 | 146542 | 3 | 2 | 15 | |
| TCGA | ZNF688 | 146542 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of ZNF688:
Generating mutation plots.
Highly correlated genes for ZNF688:
Showing top 20/207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF688 | FENDRR | 0.694217 | 3 | 0 | 3 |
| ZNF688 | TNRC6C | 0.684725 | 3 | 0 | 3 |
| ZNF688 | TOX | 0.681356 | 4 | 0 | 3 |
| ZNF688 | DPT | 0.674796 | 3 | 0 | 3 |
| ZNF688 | TCEAL3 | 0.655573 | 3 | 0 | 3 |
| ZNF688 | UQCRFS1 | 0.65454 | 4 | 0 | 4 |
| ZNF688 | RING1 | 0.650508 | 4 | 0 | 3 |
| ZNF688 | MAP2K5 | 0.649955 | 4 | 0 | 3 |
| ZNF688 | NCOR2 | 0.646936 | 3 | 0 | 3 |
| ZNF688 | ALDH1L2 | 0.646297 | 3 | 0 | 3 |
| ZNF688 | NUDT16 | 0.645406 | 3 | 0 | 3 |
| ZNF688 | ODF3B | 0.642736 | 3 | 0 | 3 |
| ZNF688 | CACNA1A | 0.641733 | 3 | 0 | 3 |
| ZNF688 | RASSF8 | 0.637361 | 3 | 0 | 3 |
| ZNF688 | KLHL13 | 0.637049 | 4 | 0 | 4 |
| ZNF688 | GRAMD1A | 0.636953 | 3 | 0 | 3 |
| ZNF688 | HEXIM2 | 0.636465 | 3 | 0 | 3 |
| ZNF688 | NSMCE4A | 0.635772 | 3 | 0 | 3 |
| ZNF688 | TRIM68 | 0.632422 | 5 | 0 | 3 |
| ZNF688 | FBLN1 | 0.630137 | 3 | 0 | 3 |
For details and further investigation, click here
