| Full name: ATP binding cassette subfamily D member 1 | Alias Symbol: AMN|ALDP|adrenoleukodystrophy | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 215 | HGNC ID: HGNC:61 | Ensembl Gene: ENSG00000101986 | OMIM ID: 300371 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ABCD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCD1 | 215 | 205142_x_at | 0.2234 | 0.3917 | |
| GSE20347 | ABCD1 | 215 | 205142_x_at | 0.2316 | 0.0203 | |
| GSE23400 | ABCD1 | 215 | 205142_x_at | -0.0198 | 0.7186 | |
| GSE26886 | ABCD1 | 215 | 205142_x_at | 0.2746 | 0.0414 | |
| GSE29001 | ABCD1 | 215 | 205142_x_at | 0.0608 | 0.7740 | |
| GSE38129 | ABCD1 | 215 | 205142_x_at | 0.0013 | 0.9909 | |
| GSE45670 | ABCD1 | 215 | 205142_x_at | 0.1128 | 0.1468 | |
| GSE53622 | ABCD1 | 215 | 129540 | 0.8488 | 0.0000 | |
| GSE53624 | ABCD1 | 215 | 129540 | 1.0412 | 0.0000 | |
| GSE63941 | ABCD1 | 215 | 205142_x_at | 0.5417 | 0.1002 | |
| GSE77861 | ABCD1 | 215 | 205142_x_at | 0.0406 | 0.8198 | |
| GSE97050 | ABCD1 | 215 | A_33_P3224660 | -0.7606 | 0.1711 | |
| SRP064894 | ABCD1 | 215 | RNAseq | 1.2379 | 0.0000 | |
| SRP133303 | ABCD1 | 215 | RNAseq | 1.0309 | 0.0000 | |
| SRP159526 | ABCD1 | 215 | RNAseq | 0.9154 | 0.0014 | |
| SRP193095 | ABCD1 | 215 | RNAseq | 1.0825 | 0.0000 | |
| SRP219564 | ABCD1 | 215 | RNAseq | 0.8352 | 0.1118 | |
| TCGA | ABCD1 | 215 | RNAseq | 0.1147 | 0.1444 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ABCD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCD1:
No record found for this gene.
Somatic mutations of ABCD1:
Generating mutation plots.
Highly correlated genes for ABCD1:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCD1 | ABTB1 | 0.721968 | 3 | 0 | 3 |
| ABCD1 | LRCH4 | 0.71587 | 3 | 0 | 3 |
| ABCD1 | FUZ | 0.711084 | 3 | 0 | 3 |
| ABCD1 | NXNL1 | 0.71052 | 3 | 0 | 3 |
| ABCD1 | CEBPE | 0.700685 | 3 | 0 | 3 |
| ABCD1 | TCTE3 | 0.683087 | 3 | 0 | 3 |
| ABCD1 | SCLY | 0.680123 | 3 | 0 | 3 |
| ABCD1 | CLDN14 | 0.677486 | 4 | 0 | 4 |
| ABCD1 | HOXB9 | 0.676726 | 4 | 0 | 4 |
| ABCD1 | PGP | 0.669193 | 3 | 0 | 3 |
| ABCD1 | ADRA2C | 0.664636 | 5 | 0 | 4 |
| ABCD1 | SPRN | 0.659789 | 4 | 0 | 3 |
| ABCD1 | TRPM3 | 0.654828 | 4 | 0 | 3 |
| ABCD1 | ACTL6B | 0.649758 | 4 | 0 | 3 |
| ABCD1 | SPEF1 | 0.64904 | 5 | 0 | 3 |
| ABCD1 | MYOD1 | 0.647463 | 4 | 0 | 3 |
| ABCD1 | PLA2G2D | 0.647415 | 5 | 0 | 4 |
| ABCD1 | LRRC72 | 0.644845 | 4 | 0 | 3 |
| ABCD1 | SLC5A11 | 0.64243 | 4 | 0 | 3 |
| ABCD1 | METTL7B | 0.639325 | 3 | 0 | 3 |
For details and further investigation, click here
