ABHD14A

 

Full name: abhydrolase domain containing 14A Alias Symbol: DKFZP564O243|DORZ1
Type: protein-coding gene Cytoband: 3p21.2
Entrez ID: 25864 HGNC ID: HGNC:24538 Ensembl Gene: ENSG00000248487 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ABHD14A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 ABHD14A 25864 14064 -1.7290 0.0000
GSE53624 ABHD14A 25864 14064 -1.3191 0.0000
GSE97050 ABHD14A 25864 A_33_P3283713 -0.2268 0.7166
SRP007169 ABHD14A 25864 RNAseq 0.8311 0.1883
SRP064894 ABHD14A 25864 RNAseq 0.2417 0.5681
SRP133303 ABHD14A 25864 RNAseq -0.3462 0.1443
SRP159526 ABHD14A 25864 RNAseq -0.1750 0.6441
SRP193095 ABHD14A 25864 RNAseq -0.1003 0.6742
SRP219564 ABHD14A 25864 RNAseq 0.3349 0.5107
TCGA ABHD14A 25864 RNAseq -0.3816 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by ABHD14A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABHD14A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABHD14A 25864 0 18 12
GSE20123 ABHD14A 25864 0 19 11
GSE43470 ABHD14A 25864 0 18 25
GSE46452 ABHD14A 25864 2 17 40
GSE47630 ABHD14A 25864 1 24 15
GSE54993 ABHD14A 25864 6 2 62
GSE54994 ABHD14A 25864 0 34 19
GSE60625 ABHD14A 25864 5 0 6
GSE74703 ABHD14A 25864 0 14 22
GSE74704 ABHD14A 25864 0 12 8
TCGA ABHD14A 25864 0 78 18

Total number of gains: 14; Total number of losses: 236; Total Number of normals: 238.  


 

Somatic mutations of ABHD14A:

 

Generating mutation plots.

 

Highly correlated genes for ABHD14A:

 

Showing top 20/129 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABHD14AUBL30.783749303
ABHD14AELN0.762143303
ABHD14ASH3BGRL20.751335303
ABHD14AIL11RA0.749615303
ABHD14APHACTR20.747919303
ABHD14AUPK1A0.746237303
ABHD14AKRT780.745061303
ABHD14AMORN30.740573303
ABHD14AAIF1L0.730652303
ABHD14ALPIN10.728749303
ABHD14ATP53I30.727798303
ABHD14ATECPR10.726162303
ABHD14AIKZF20.725767303
ABHD14AFAM3D0.724336303
ABHD14AVSIG20.723188303
ABHD14AABCA50.72114303
ABHD14AYOD10.71947303
ABHD14ATRIP100.716757303
ABHD14AVAT10.716485303
ABHD14AC1orf1160.714608303

For details and further investigation, click here