| Full name: ATP binding cassette subfamily A member 5 | Alias Symbol: EST90625 | ||
| Type: protein-coding gene | Cytoband: 17q24.3 | ||
| Entrez ID: 23461 | HGNC ID: HGNC:35 | Ensembl Gene: ENSG00000154265 | OMIM ID: 612503 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCA5 | 23461 | 213353_at | -0.9656 | 0.0528 | |
| GSE20347 | ABCA5 | 23461 | 213353_at | -1.1285 | 0.0000 | |
| GSE23400 | ABCA5 | 23461 | 213353_at | -0.5490 | 0.0000 | |
| GSE26886 | ABCA5 | 23461 | 213353_at | -1.4665 | 0.0000 | |
| GSE29001 | ABCA5 | 23461 | 213353_at | -1.1663 | 0.0116 | |
| GSE38129 | ABCA5 | 23461 | 213353_at | -0.8902 | 0.0002 | |
| GSE45670 | ABCA5 | 23461 | 213353_at | -0.3963 | 0.0683 | |
| GSE53622 | ABCA5 | 23461 | 120855 | -1.2148 | 0.0000 | |
| GSE53624 | ABCA5 | 23461 | 120855 | -1.4447 | 0.0000 | |
| GSE63941 | ABCA5 | 23461 | 213353_at | -1.3217 | 0.0351 | |
| GSE77861 | ABCA5 | 23461 | 213353_at | -0.1070 | 0.6695 | |
| GSE97050 | ABCA5 | 23461 | A_23_P78018 | -0.4502 | 0.2791 | |
| SRP007169 | ABCA5 | 23461 | RNAseq | -1.1568 | 0.0291 | |
| SRP008496 | ABCA5 | 23461 | RNAseq | -1.2659 | 0.0000 | |
| SRP064894 | ABCA5 | 23461 | RNAseq | -1.2122 | 0.0000 | |
| SRP133303 | ABCA5 | 23461 | RNAseq | -0.7117 | 0.0113 | |
| SRP159526 | ABCA5 | 23461 | RNAseq | -0.7521 | 0.0633 | |
| SRP193095 | ABCA5 | 23461 | RNAseq | -1.4195 | 0.0000 | |
| SRP219564 | ABCA5 | 23461 | RNAseq | -0.7379 | 0.1706 | |
| TCGA | ABCA5 | 23461 | RNAseq | -0.3091 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by ABCA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCA5 | 23461 | 3 | 1 | 26 | |
| GSE20123 | ABCA5 | 23461 | 3 | 1 | 26 | |
| GSE43470 | ABCA5 | 23461 | 6 | 0 | 37 | |
| GSE46452 | ABCA5 | 23461 | 31 | 1 | 27 | |
| GSE47630 | ABCA5 | 23461 | 7 | 1 | 32 | |
| GSE54993 | ABCA5 | 23461 | 2 | 5 | 63 | |
| GSE54994 | ABCA5 | 23461 | 9 | 4 | 40 | |
| GSE60625 | ABCA5 | 23461 | 4 | 3 | 4 | |
| GSE74703 | ABCA5 | 23461 | 6 | 0 | 30 | |
| GSE74704 | ABCA5 | 23461 | 3 | 1 | 16 | |
| TCGA | ABCA5 | 23461 | 31 | 10 | 55 |
Total number of gains: 105; Total number of losses: 27; Total Number of normals: 356.
Somatic mutations of ABCA5:
Generating mutation plots.
Highly correlated genes for ABCA5:
Showing top 20/1122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCA5 | GBP6 | 0.761952 | 3 | 0 | 3 |
| ABCA5 | SLC10A5 | 0.761651 | 3 | 0 | 3 |
| ABCA5 | SFTPB | 0.74511 | 3 | 0 | 3 |
| ABCA5 | PLCD1 | 0.739039 | 10 | 0 | 10 |
| ABCA5 | KRT78 | 0.73558 | 6 | 0 | 6 |
| ABCA5 | CASC3 | 0.734786 | 3 | 0 | 3 |
| ABCA5 | CYSRT1 | 0.734265 | 5 | 0 | 5 |
| ABCA5 | SCEL | 0.721954 | 9 | 0 | 9 |
| ABCA5 | ABHD14A | 0.72114 | 3 | 0 | 3 |
| ABCA5 | SAMD5 | 0.720396 | 7 | 0 | 6 |
| ABCA5 | SIM2 | 0.719868 | 10 | 0 | 10 |
| ABCA5 | ALDH3A2 | 0.719491 | 10 | 0 | 10 |
| ABCA5 | CA13 | 0.715391 | 3 | 0 | 3 |
| ABCA5 | ULK3 | 0.714332 | 6 | 0 | 6 |
| ABCA5 | TFAP2B | 0.709538 | 8 | 0 | 8 |
| ABCA5 | EPS8L2 | 0.708396 | 10 | 0 | 9 |
| ABCA5 | SFTA2 | 0.707766 | 3 | 0 | 3 |
| ABCA5 | SLC46A2 | 0.707046 | 6 | 0 | 6 |
| ABCA5 | HCG22 | 0.702507 | 5 | 0 | 5 |
| ABCA5 | PRSS27 | 0.701844 | 5 | 0 | 5 |
For details and further investigation, click here
