| Full name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A | Alias Symbol: GnT-Iva|GnT-4a | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 11320 | HGNC ID: HGNC:7047 | Ensembl Gene: ENSG00000071073 | OMIM ID: 604623 |
| Drug and gene relationship at DGIdb | |||
Expression of MGAT4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGAT4A | 11320 | 226039_at | 0.1953 | 0.8501 | |
| GSE20347 | MGAT4A | 11320 | 219797_at | -0.2370 | 0.0098 | |
| GSE23400 | MGAT4A | 11320 | 219797_at | -0.0906 | 0.0160 | |
| GSE26886 | MGAT4A | 11320 | 226039_at | -1.5173 | 0.0003 | |
| GSE29001 | MGAT4A | 11320 | 219797_at | -0.1426 | 0.7136 | |
| GSE38129 | MGAT4A | 11320 | 219797_at | -0.1544 | 0.1653 | |
| GSE45670 | MGAT4A | 11320 | 226039_at | -0.7151 | 0.0323 | |
| GSE53622 | MGAT4A | 11320 | 53811 | -0.5902 | 0.0000 | |
| GSE53624 | MGAT4A | 11320 | 53811 | -0.6924 | 0.0000 | |
| GSE63941 | MGAT4A | 11320 | 226039_at | 0.0197 | 0.9869 | |
| GSE77861 | MGAT4A | 11320 | 226039_at | -0.3022 | 0.1868 | |
| GSE97050 | MGAT4A | 11320 | A_23_P28507 | -0.0073 | 0.9885 | |
| SRP007169 | MGAT4A | 11320 | RNAseq | 0.3022 | 0.5815 | |
| SRP008496 | MGAT4A | 11320 | RNAseq | 0.0440 | 0.9046 | |
| SRP064894 | MGAT4A | 11320 | RNAseq | -0.0506 | 0.8453 | |
| SRP133303 | MGAT4A | 11320 | RNAseq | -0.0704 | 0.6934 | |
| SRP159526 | MGAT4A | 11320 | RNAseq | 0.7976 | 0.2468 | |
| SRP193095 | MGAT4A | 11320 | RNAseq | -0.8714 | 0.0022 | |
| SRP219564 | MGAT4A | 11320 | RNAseq | 0.0090 | 0.9769 | |
| TCGA | MGAT4A | 11320 | RNAseq | -0.6344 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MGAT4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MGAT4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGAT4A | 11320 | 6 | 2 | 22 | |
| GSE20123 | MGAT4A | 11320 | 6 | 2 | 22 | |
| GSE43470 | MGAT4A | 11320 | 3 | 2 | 38 | |
| GSE46452 | MGAT4A | 11320 | 2 | 3 | 54 | |
| GSE47630 | MGAT4A | 11320 | 7 | 0 | 33 | |
| GSE54993 | MGAT4A | 11320 | 0 | 6 | 64 | |
| GSE54994 | MGAT4A | 11320 | 10 | 0 | 43 | |
| GSE60625 | MGAT4A | 11320 | 0 | 3 | 8 | |
| GSE74703 | MGAT4A | 11320 | 3 | 2 | 31 | |
| GSE74704 | MGAT4A | 11320 | 4 | 1 | 15 | |
| TCGA | MGAT4A | 11320 | 33 | 5 | 58 |
Total number of gains: 74; Total number of losses: 26; Total Number of normals: 388.
Somatic mutations of MGAT4A:
Generating mutation plots.
Highly correlated genes for MGAT4A:
Showing top 20/710 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGAT4A | TXNL4A | 0.765779 | 3 | 0 | 3 |
| MGAT4A | WDR77 | 0.763497 | 3 | 0 | 3 |
| MGAT4A | RPP38 | 0.757636 | 3 | 0 | 3 |
| MGAT4A | ARHGAP15 | 0.745788 | 4 | 0 | 4 |
| MGAT4A | UBE2D2 | 0.737509 | 3 | 0 | 3 |
| MGAT4A | NDUFA9 | 0.734682 | 3 | 0 | 3 |
| MGAT4A | ANKRD44 | 0.732141 | 6 | 0 | 6 |
| MGAT4A | TBC1D20 | 0.725009 | 3 | 0 | 3 |
| MGAT4A | CSNK2B | 0.715463 | 3 | 0 | 3 |
| MGAT4A | GRB2 | 0.71011 | 3 | 0 | 3 |
| MGAT4A | RCOR3 | 0.705095 | 3 | 0 | 3 |
| MGAT4A | USP3 | 0.704256 | 3 | 0 | 3 |
| MGAT4A | GPD2 | 0.700622 | 3 | 0 | 3 |
| MGAT4A | USP30 | 0.69929 | 3 | 0 | 3 |
| MGAT4A | CASP3 | 0.694332 | 7 | 0 | 5 |
| MGAT4A | GIMAP7 | 0.693967 | 7 | 0 | 6 |
| MGAT4A | THSD7A | 0.684107 | 4 | 0 | 4 |
| MGAT4A | ABHD3 | 0.684082 | 4 | 0 | 3 |
| MGAT4A | RASAL2 | 0.683402 | 3 | 0 | 3 |
| MGAT4A | GIMAP5 | 0.680775 | 4 | 0 | 3 |
For details and further investigation, click here
