| Full name: solute carrier family 33 member 1 | Alias Symbol: AT-1|AT1 | ||
| Type: protein-coding gene | Cytoband: 3q25.31 | ||
| Entrez ID: 9197 | HGNC ID: HGNC:95 | Ensembl Gene: ENSG00000169359 | OMIM ID: 603690 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC33A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC33A1 | 9197 | 203164_at | 0.9578 | 0.0464 | |
| GSE20347 | SLC33A1 | 9197 | 203164_at | 1.0051 | 0.0000 | |
| GSE23400 | SLC33A1 | 9197 | 203164_at | 1.1922 | 0.0000 | |
| GSE26886 | SLC33A1 | 9197 | 203164_at | 0.4143 | 0.1146 | |
| GSE29001 | SLC33A1 | 9197 | 203164_at | 1.1373 | 0.0001 | |
| GSE38129 | SLC33A1 | 9197 | 203164_at | 0.9851 | 0.0000 | |
| GSE45670 | SLC33A1 | 9197 | 203164_at | 0.7238 | 0.0021 | |
| GSE53622 | SLC33A1 | 9197 | 99829 | 0.7417 | 0.0000 | |
| GSE53624 | SLC33A1 | 9197 | 99829 | 0.8807 | 0.0000 | |
| GSE63941 | SLC33A1 | 9197 | 1554148_a_at | 0.6593 | 0.2034 | |
| GSE77861 | SLC33A1 | 9197 | 203164_at | 0.8055 | 0.0182 | |
| GSE97050 | SLC33A1 | 9197 | A_33_P3251108 | 0.5694 | 0.1737 | |
| SRP007169 | SLC33A1 | 9197 | RNAseq | 1.0928 | 0.0058 | |
| SRP008496 | SLC33A1 | 9197 | RNAseq | 1.0537 | 0.0001 | |
| SRP064894 | SLC33A1 | 9197 | RNAseq | 0.8206 | 0.0025 | |
| SRP133303 | SLC33A1 | 9197 | RNAseq | 0.8973 | 0.0000 | |
| SRP159526 | SLC33A1 | 9197 | RNAseq | 1.2316 | 0.0008 | |
| SRP193095 | SLC33A1 | 9197 | RNAseq | 0.5079 | 0.0003 | |
| SRP219564 | SLC33A1 | 9197 | RNAseq | 0.8513 | 0.0374 | |
| TCGA | SLC33A1 | 9197 | RNAseq | 0.0504 | 0.3603 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SLC33A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC33A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC33A1 | 9197 | 21 | 1 | 8 | |
| GSE20123 | SLC33A1 | 9197 | 21 | 1 | 8 | |
| GSE43470 | SLC33A1 | 9197 | 23 | 0 | 20 | |
| GSE46452 | SLC33A1 | 9197 | 18 | 2 | 39 | |
| GSE47630 | SLC33A1 | 9197 | 19 | 3 | 18 | |
| GSE54993 | SLC33A1 | 9197 | 1 | 11 | 58 | |
| GSE54994 | SLC33A1 | 9197 | 38 | 1 | 14 | |
| GSE60625 | SLC33A1 | 9197 | 0 | 6 | 5 | |
| GSE74703 | SLC33A1 | 9197 | 20 | 0 | 16 | |
| GSE74704 | SLC33A1 | 9197 | 14 | 0 | 6 | |
| TCGA | SLC33A1 | 9197 | 73 | 1 | 22 |
Total number of gains: 248; Total number of losses: 26; Total Number of normals: 214.
Somatic mutations of SLC33A1:
Generating mutation plots.
Highly correlated genes for SLC33A1:
Showing top 20/1804 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC33A1 | GMPS | 0.786008 | 13 | 0 | 13 |
| SLC33A1 | PNKP | 0.7852 | 3 | 0 | 3 |
| SLC33A1 | PHF6 | 0.777337 | 3 | 0 | 3 |
| SLC33A1 | SLC39A3 | 0.772857 | 3 | 0 | 3 |
| SLC33A1 | XRN1 | 0.75139 | 3 | 0 | 3 |
| SLC33A1 | ZNF765 | 0.743787 | 3 | 0 | 3 |
| SLC33A1 | DNAJB11 | 0.741875 | 7 | 0 | 6 |
| SLC33A1 | ZNF284 | 0.74072 | 3 | 0 | 3 |
| SLC33A1 | ATP2C1 | 0.739051 | 11 | 0 | 10 |
| SLC33A1 | SMCR8 | 0.734765 | 3 | 0 | 3 |
| SLC33A1 | ACAP2 | 0.734543 | 3 | 0 | 3 |
| SLC33A1 | SEC61A1 | 0.729666 | 9 | 0 | 7 |
| SLC33A1 | RNF7 | 0.726915 | 11 | 0 | 9 |
| SLC33A1 | TOPBP1 | 0.72532 | 12 | 0 | 12 |
| SLC33A1 | ZBTB9 | 0.723783 | 5 | 0 | 5 |
| SLC33A1 | U2SURP | 0.72368 | 10 | 0 | 9 |
| SLC33A1 | LRRC58 | 0.72072 | 5 | 0 | 4 |
| SLC33A1 | ATR | 0.72034 | 11 | 0 | 11 |
| SLC33A1 | G2E3 | 0.718995 | 5 | 0 | 5 |
| SLC33A1 | ECT2 | 0.714693 | 11 | 0 | 9 |
For details and further investigation, click here
