CCDC77

 

Full name: coiled-coil domain containing 77 Alias Symbol: MGC13183
Type: protein-coding gene Cytoband: 12p13.33
Entrez ID: 84318 HGNC ID: HGNC:28203 Ensembl Gene: ENSG00000120647 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC77:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC77 84318 224521_s_at 0.3444 0.5650
GSE26886 CCDC77 84318 224521_s_at -0.3309 0.4002
GSE45670 CCDC77 84318 224521_s_at 0.9118 0.0020
GSE53622 CCDC77 84318 10572 0.5973 0.0000
GSE53624 CCDC77 84318 10572 0.8057 0.0000
GSE63941 CCDC77 84318 224521_s_at 0.1704 0.7910
GSE77861 CCDC77 84318 224521_s_at 0.3728 0.1196
GSE97050 CCDC77 84318 A_23_P99172 0.3359 0.2385
SRP007169 CCDC77 84318 RNAseq 1.0357 0.1307
SRP008496 CCDC77 84318 RNAseq 1.2056 0.0160
SRP064894 CCDC77 84318 RNAseq 0.6974 0.0001
SRP133303 CCDC77 84318 RNAseq 0.7198 0.0089
SRP159526 CCDC77 84318 RNAseq 0.6666 0.0112
SRP193095 CCDC77 84318 RNAseq 0.6762 0.0000
SRP219564 CCDC77 84318 RNAseq 0.7992 0.0029
TCGA CCDC77 84318 RNAseq 0.6617 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by CCDC77 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC77:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC77 84318 8 4 18
GSE20123 CCDC77 84318 7 4 19
GSE43470 CCDC77 84318 8 3 32
GSE46452 CCDC77 84318 10 1 48
GSE47630 CCDC77 84318 12 2 26
GSE54993 CCDC77 84318 1 10 59
GSE54994 CCDC77 84318 10 2 41
GSE60625 CCDC77 84318 0 1 10
GSE74703 CCDC77 84318 7 2 27
GSE74704 CCDC77 84318 4 2 14
TCGA CCDC77 84318 41 7 48

Total number of gains: 108; Total number of losses: 38; Total Number of normals: 342.  

 

Somatic mutations of CCDC77:

 

Generating mutation plots.

 

Highly correlated genes for CCDC77:

 

Showing top 20/716 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC77M6PR0.758305404
CCDC77PHB20.739744606
CCDC77NIPA20.730482303
CCDC77TSEN540.729863303
CCDC77MCM70.724936606
CCDC77RCN20.723896303
CCDC77CDC450.720256606
CCDC77RAD51AP10.701598807
CCDC77TAF1A0.695845505
CCDC77LSM80.695716303
CCDC77MCM20.692883606
CCDC77MRPL510.691591706
CCDC77SPAG50.690438605
CCDC77ACTR3B0.689986303
CCDC77HPS30.689397303
CCDC77ASF1B0.682738605
CCDC77CDK10.681002706
CCDC77ECE20.676752606
CCDC77POLR3K0.674498606
CCDC77CKS1B0.67199605

For details and further investigation, click here